Cheap Flights from Panama City to Santa Cruz Department from 411 € Return

Flight deals from Panama City to Santa Cruz Department

Looking for cheap tickets from Panama City to Santa Cruz Department, or a last-minute trip? Find the lowest prices on one-way and return tickets right here.

Santa Cruz.411 € per passenger.Departing Mon, 2 Mar, returning Thu, 5 Mar.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 2 Mar, arriving in Santa Cruz Viru Viru.Inbound indirect flight with Avianca, departs from Santa Cruz Viru Viru on Thu, 5 Mar, arriving in Panama City Tocumen International.Price includes taxes and charges.From 411 €, select.

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Flying from Panama City to Santa Cruz Department

Arm yourself with these facts on the fly.

Cheapest flight found	411 €
Cheapest month to fly	March
Average flight time	4 hrs, 58 mins
Cheapest airport to fly from	Panama City Tocumen International
Most popular airline	Copa

How to find cheap flights from Panama City to Santa Cruz Department

We've compared the best online travel agents and flight providers on the internet to find the cheapest plane tickets from Panama City to Santa Cruz Department. Other savvy travellers recently found return flights from 411 € and one-way tickets from 220 € one-way. Ready to join them? Here are a few tips to help you do it the smart way.

Fly from Panama City Tocumen International into Santa Cruz Viru Viru

At the moment, the lowest priced flight tickets to Santa Cruz Department are from Panama City Tocumen International Airport to Santa Cruz Viru Viru Airport.

Fly in March

We crunched the flight calendar and found the cheapest time to fly from Panama City to Santa Cruz Department is currently March.

Flex your dates for the best rates

If you’re flexible on your departure dates, you can use Skyscanner's whole month tool to find the cheapest day of the year to fly from Panama City to anywhere you choose in Santa Cruz Department.

Watch as fares rise and fall

With Price Alerts, we'll let you know when flight prices from Panama City to Santa Cruz Department go up or down so you can book when the time is just right.

Relax – these are fee-free flight tickets

With us, there are no added fees – the Santa Cruz Department to Santa Cruz Department flight price you see when you search with us is what you pay to the provider.

Frequently asked questions

What's the average Panama City to Santa Cruz Department flight price?

We looked at all of the upcoming return flights from Panama City to Santa Cruz Department we could find over the next 12 months. It looks like 411 € is the best price. This is good, compared to the average Santa Cruz Department ticket price of 411 €.

What is the cheapest month to fly from Panama City to Santa Cruz Department?

The cheapest month to fly from Panama City to Santa Cruz Department is currently March.

Which upcoming date is cheapest to fly from Panama City to Santa Cruz Department on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Santa Cruz Department on Monday, 2 March 2026.

Are there any direct flights from Panama City to Santa Cruz Department?

Panama City Tocumen International Airport offers direct flights to Santa Cruz Department.

If I'm flying from Panama City, where in Santa Cruz Department is cheapest to fly into?

If you're flying from Panama City, the cheapest city in Santa Cruz Department to fly into is Santa Cruz. The cheapest airport serving Santa Cruz at the moment is Santa Cruz Viru Viru.

How long is the flight from Panama City to Santa Cruz Department?

The average flight time between Panama City and Santa Cruz Department is 4 hours and 58 minutes.

Flights from Panama City to Santa Cruz Department