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416 € Cheap Flights from Detroit Wayne County (DTW) to Panama City (PTYA)

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Flight deals from Detroit Wayne County to Panama City

Looking for a cheap last-minute deal or the best return flight from Detroit Wayne County to Panama City? Find the lowest prices on one-way and return tickets right here.
Panama City.416 € per passenger.Departing Mon, 26 Jan, returning Mon, 2 Mar.Return flight with Frontier Airlines and Avianca.Outbound indirect flight with Frontier Airlines, departs from Detroit Wayne County on Mon, 26 Jan, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 2 Mar, arriving in Detroit Wayne County.Price includes taxes and charges.From 416 €, select.
Panama City.424 € per passenger.Departing Thu, 22 Jan, returning Thu, 29 Jan.Return flight with Spirit Airlines and Avianca.Outbound indirect flight with Spirit Airlines, departs from Detroit Wayne County on Thu, 22 Jan, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Thu, 29 Jan, arriving in Detroit Wayne County.Price includes taxes and charges.From 424 €, select.
Panama City.432 € per passenger.Departing Sat, 31 Jan, returning Sun, 8 Feb.Return flight with Spirit Airlines and Avianca.Outbound indirect flight with Spirit Airlines, departs from Detroit Wayne County on Sat, 31 Jan, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Sun, 8 Feb, arriving in Detroit Wayne County.Price includes taxes and charges.From 432 €, select.
Panama City.439 € per passenger.Departing Fri, 20 Feb, returning Fri, 27 Feb.Return flight with Spirit Airlines and Avianca.Outbound indirect flight with Spirit Airlines, departs from Detroit Wayne County on Fri, 20 Feb, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Fri, 27 Feb, arriving in Detroit Wayne County.Price includes taxes and charges.From 439 €, select.
Panama City.480 € per passenger.Departing Wed, 4 Mar, returning Sun, 8 Mar.Return flight with Spirit Airlines and Avianca.Outbound indirect flight with Spirit Airlines, departs from Detroit Wayne County on Wed, 4 Mar, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Sun, 8 Mar, arriving in Detroit Wayne County.Price includes taxes and charges.From 480 €, select.
Panama City.514 € per passenger.Departing Fri, 27 Feb, returning Sat, 7 Mar.Return flight with Frontier Airlines and Avianca.Outbound indirect flight with Frontier Airlines, departs from Detroit Wayne County on Fri, 27 Feb, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Sat, 7 Mar, arriving in Detroit Wayne County.Price includes taxes and charges.From 514 €, select.
Panama City.583 € per passenger.Departing Mon, 6 Apr, returning Sun, 12 Apr.Return flight with Spirit Airlines and Avianca.Outbound indirect flight with Spirit Airlines, departs from Detroit Wayne County on Mon, 6 Apr, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Sun, 12 Apr, arriving in Detroit Wayne County.Price includes taxes and charges.From 583 €, select.
Panama City.612 € per passenger.Departing Wed, 10 Dec, returning Wed, 17 Dec.Return flight with Spirit Airlines and Avianca.Outbound indirect flight with Spirit Airlines, departs from Detroit Wayne County on Wed, 10 Dec, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Wed, 17 Dec, arriving in Detroit Wayne County.Price includes taxes and charges.From 612 €, select.
Map with a flight path from Detroit Wayne County to Panama City. A plane icon is halfway along the route with a label that says "1+ stops".
1+ stops

Your route at a glance

Cheapest deal416 €
Cheapest monthJanuary
Most popular airlineUnited

Find the cheapest month to fly from Detroit Wayne County to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Detroit Wayne County to Panama City flights are currently cheapest in January.
Dec
from 612 €
Jan
from 424 €
Feb
from 439 €
Mar
from 480 €
Apr
from 583 €
May
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Jun
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Jul
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Aug
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Sep
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Oct
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Nov
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Alternative Detroit Wayne County to Panama City routes

Looking for the cheapest, fastest or easiest route from Detroit Wayne County to Panama City? You could fly into the following airports instead.

Finding cheap flights from Detroit Wayne County to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a return flight from Detroit Wayne County to Panama City is 416 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Detroit Wayne County to Panama City. But we found flights with one or more stops from 416 €.
As of December 2025, there are no flights flying from Detroit Wayne County to Panama City.
The cheapest month to fly from Detroit Wayne County to Panama City is usually January.
If you're flying from Detroit Wayne County Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from 416 €.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Detroit Wayne County Airport to Panama City on Monday, 26 January 2026.
No airlines currently offer direct flights between Detroit Wayne County Airport and Panama City. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.
In December, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
Currently, Frontier Airlines offers the cheapest flight tickets to Panama City.

Travelling from Detroit Metropolitan Wayne County Airport (DTW) to Panama City: what you need to know

  • Panama City is one hour behind Detroit, where Detroit Metropolitan Wayne County Airport is located. Panama City runs on the UTC-5 timezone.

  • For a relaxed start to your DTW to Panama City flight, leave enough time to navigate the airport and find your gate. Turning up two hours before international departures and an hour before domestic flights is the general travel rule.

  • If you're flying during a bank holiday or another peak period, give yourself extra time. A good general rule is two hours before domestic flights and up to four hours before international departures. Security and check-in lines will be longer.

  • Consider adding a stopover to potentially score a cheaper plane ticket from DTW to Panama City. Simply uncheck 'Direct flights only' during your search. Break up your journey by stopping at one of these popular airports:

    • Miami International Airport (MIA)

    • Orlando International Airport (MCO)

    • Cancun International Airport (CUN)

  • Travelling from central Detroit to DTW takes around 1 hour 10 minutes by public transport. If you ride-share, drive or take a cab, you'll cover the 29 kilometres in 25 minutes or so, depending on traffic.

  • Want a stress-free start to your holiday? Stay near DTW. Whether you're catching an early flight from Detroit Metropolitan Wayne County Airport to Panama City or just don't want to be rushed, these hotels are just the thing:

  • 75.1% of flights leaving from Detroit Metropolitan Wayne County Airport make it to their destination on schedule.

  • DTW is located at 1 Detroit Metro Airport.

How to find the cheapest flights from Detroit Metropolitan Wayne County Airport (DTW) to Panama City

  • 152 € is currently the best price for a one-way Detroit Metropolitan Wayne County Airport to Panama City flight. Return plane tickets start from 416 €. These fares can change depending on availability.

  • Booking early is often the key to securing a cheap flight from DTW to Panama City. Prices tend to rise as demand increases, so the closer your departure date, the more expensive your ticket may be.

  • If you're willing to be flexible with your trip dates, check out the 'Whole month' search tool. It'll show you the lowest price across each month when searching for your Detroit Metropolitan Wayne County Airport to Panama City ticket.

  • You don't need to keep checking in to find out if fares have dropped when you create a Price Alert. We'll update you when there's an even bigger deal on cheap flights from DTW to Panama City.

  • Save money on your flight from Detroit Metropolitan Wayne County Airport to Panama City with the help of our filters. Select your ideal duration, departure time and airlines, then sort the results by 'Cheapest' for the best deals.

Airports in Panama City

Tocumen International Airport (PTY)

  • Tocumen International Airport (PTY) is around 21 kilometres from central Panama City. If you're grabbing a cab or a ride-share, the drive takes roughly 20 minutes.

  • Travelling to the centre on public transport takes about 1 hour 5 minutes.

  • Look into staying at a hotel close to PTY if you have a late flight from Detroit Metropolitan Wayne County Airport to Panama City. Pick one of these options and make your first night all about rest:

  • Pick up a Tocumen International Airport rental car and discover Panama City and beyond with your own wheels. Avis, Dollar and MEX are top outlets you can book with here.

  • Booking your ride from Tocumen International Airport around three weeks in advance of your flight from DTW to Panama City can help you secure the lowest rate.

Marcos A. Gelabert International Airport (PAC)

  • The centre of Panama City is about 2 kilometres from Marcos A. Gelabert International Airport (PAC). Once your flight from Detroit Metropolitan Wayne County Airport to Panama City has landed and you've made your way through the terminal, expect a drive of around 5 minutes.

  • If you choose to travel on public transport, you'll reach the centre in 25 minutes or so.

  • After stepping off your DTW to Panama City flight, unwind at a hotel near PAC. These are some comfortable options that'll help you switch to relaxation mode:

  • Thrifty, Avis and Alamo make collecting a Marcos A. Gelabert International Airport rental car quick and easy. These suppliers are located in or around the terminal and will have you on your way in a heartbeat.

  • Score the best price by reserving your ride from PAC three weeks in advance. You'll also have access to a bigger selection of vehicles.

Panama Pacifico Airport (BLB)

  • Step off your flight from Detroit Metropolitan Wayne County Airport to Panama City and go straight to your hotel or start discovering the city right away. The centre of Panama City is around 16 kilometres from Panama Pacifico Airport (BLB) and usually takes 20 minutes to drive there.

  • Book a hotel near BLB and go from the plane to your bed in a flash. Whether you have a late DTW to Panama City flight or just want an easier arrival, these stays offer convenience when you need it most:

  • Take control of the next chapter of your journey by picking up a Panama Pacifico Airport rental car. Sixt, Dollar and Thrifty make getting on the road smooth sailing.

  • Around one week ahead of your flight from Detroit Metropolitan Wayne County Airport to Panama City is the ideal time to secure your ride from BLB. You're more likely to find a cheaper rate or catch some early booking discounts.

Best time to go to Panama City

  • Before you book your flights from Detroit Metropolitan Wayne County Airport to Panama City, consider which time of year works best for you. Peak season in Panama City offers a lively atmosphere and plenty of things to do, while low season brings cheaper hotel deals and smaller crowds.

  • The warmest month in Panama City is March, with temperatures ranging between 21ºC (70ºF) and 32ºC (90ºF). Lock in your Detroit Metropolitan Wayne County Airport to Panama City plane ticket then if that's your idea of comfortable weather.

  • February sees average temperatures of between 22ºC (72ºF) and 31ºC (88ºF). Look for a cheap ticket from DTW to Panama City around that time if you want to travel when it's cooler.

More about Panama City

  • Once you've booked your flight from Detroit Metropolitan Wayne County Airport to Panama City, choose a hotel that combines comfort with a great location. Make one of these options your base for exploring Panama City:

  • All great adventures should include a little sightseeing. Casco Viejo, Panama Canal Museum and Cinta Costera are must-do's during your Panama City adventure.

Explore more of Panama

  • Panama City will leave a lasting impression, but there are so many other parts of Panama you should also see. Around 322 kilometres west of Panama City, a trip to David will fill your itinerary to the brim. Start with attractions like Parque Cervantes, Altos del Rio Park and Coquito Hills Park.

  • Around 193 kilometres south-west of Panama City, Santiago de Veraguas is another essential stop in Panama. Start your sightseeing at Santiago the Apostle Cathedral, Santiago de Veraguas, The Church of Jesus Christ of Latter Day Saints and La Placita San Juan De Dios.

Plan the rest of your trip from Detroit to Panama City

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.