303 € Cheap Flights from Sao Paulo Guarulhos to Panama City

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Flight deals from Sao Paulo Guarulhos to Panama City

Looking for a cheap last-minute deal or the best return flight from Sao Paulo Guarulhos to Panama City? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Sao Paulo Guarulhos to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Sao Paulo Guarulhos to Panama City flights are currently cheapest in March.

Direct flights from Sao Paulo Guarulhos to Panama City

Alternative Sao Paulo Guarulhos to Panama City routes

Looking for the cheapest, fastest or easiest route from Sao Paulo Guarulhos to Panama City? You could fly into the following airports instead.

Sao Paulo to Panama City: Flight information

The things to know before you go.
Cheapest flight found303 €
Cheapest month to flyFebruary
Average flight time6 hrs, 49 mins
Most popular airlineCopa
Average flights per week242

Finding cheap flights from Sao Paulo Guarulhos to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a return flight from Sao Paulo Guarulhos to Panama City is 303 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
6 hours and 49 minutes is the average flight time from Sao Paulo Guarulhos to Panama City.
Copa, Azul Airlines and Emirates fly direct from Sao Paulo Guarulhos to Panama City.
As of February 2026, there are 121 flights per week flying from Sao Paulo Guarulhos to Panama City.
The cheapest month to fly from Sao Paulo Guarulhos to Panama City is usually February.
If you're flying from Sao Paulo Guarulhos Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from 303 €.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Sao Paulo Guarulhos Airport to Panama City on Friday, 27 February 2026.
Yes – the average flight time is 6 hours and 49 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.
In February, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
Currently, Copa and Avianca offer the cheapest flight tickets to Panama City.

Travelling from Sao Paulo-Guarulhos International Airport (GRU) to Panama City: what you need to know

  • Expect to be in the air for 6 hours 45 minutes. That's the average journey time for a direct flight from Sao Paulo-Guarulhos International Airport to Panama City.

  • Sao Paulo-Guarulhos International Airport is located in Sao Paulo. Following the UTC-5 timezone, Panama City is two hours behind Sao Paulo.

  • With 35 flights a week between the two airports, Sao Paulo-Guarulhos International Airport (GRU) to Tocumen International Airport (PTY) is the most popular route. Copa Airlines operates the earliest flight at 01:25. If you'd like to make the most of your day before leaving, the last flight from GRU to PTY is with Copa Airlines at 11:20.

  • For a relaxed start to your GRU to Panama City flight, leave enough time for things like baggage drop and finding your gate. Turning up two hours ahead of international departures and one hour before domestic flights is the general rule.

  • Delays at security and check-in are more likely if you're heading away during high season, so give yourself a bit more breathing room. A good general rule for peak times? Arrive up to four hours ahead for international flights and two hours for domestic departures.

  • Start your trip at GRU and travel nonstop to Tocumen International Airport (PTY). That's where you can expect to touch down when searching for Sao Paulo-Guarulhos International Airport to Panama City tickets.

  • Keep your eyes peeled for promotions from Copa Airlines. This airline has direct flights from Sao Paulo-Guarulhos International Airport to Panama City.

  • Consider adding a stopover to potentially unlock a cheaper plane ticket from GRU to Panama City. Just uncheck 'Direct flights only' during your search. Break up your trip (and maybe save some cash) by stopping at one of these popular options:

    • El Dorado International Airport (BOG)

    • Jorge Chavez International Airport (LIM)

    • Ministro Pistarini Airport (EZE)

  • The journey from central Sao Paulo to GRU takes about 1 hour 20 minutes on public transport. If you ride-share, drive or take a cab, you'll cover the 21 kilometres in 30 minutes or so, depending on traffic.

  • Looking for a hotel close to GRU? If you've booked an early flight from Sao Paulo-Guarulhos International Airport to Panama City, these accommodation options put the terminal practically at your doorstep:

  • When it comes to Sao Paulo-Guarulhos International Airport's on-time performance, data shows 75.54% of flights stick to their scheduled arrival time.

How to find the cheapest flights from Sao Paulo-Guarulhos International Airport (GRU) to Panama City

  • 195 € is the cheapest price we've found for a one-way Sao Paulo-Guarulhos International Airport to Panama City flight. A return plane ticket right now is 303 €. Depending on when and how early you book, these fares can change.

  • Book five months before your departure date. Research on pricing trends suggests this is the ideal window for finding cheap flights from GRU to Panama City.

  • The best month for landing cheap Sao Paulo-Guarulhos International Airport to Panama City tickets is September. Use the 'Whole month' tool to compare flight prices, then select the dates offering the lowest fares.

  • Stay on top of deals for cheap flights from GRU to Panama City by setting up a Price Alert. You'll get an email or notification on the app when a new low fare is offered.

  • Find a cheap flight from Sao Paulo-Guarulhos International Airport to Panama City with the help of our filters. Select your ideal times, airlines and number of stops, then sort the results by 'Cheapest' for the best deals.

Airports in Panama City

Tocumen International Airport (PTY)

  • The distance from Tocumen International Airport (PTY) to central Panama City is roughly 21 kilometres. It takes about 20 minutes to get to the centre driving.

  • When travelling by public transport, expect a journey time of around 1 hour 5 minutes.

  • Look into staying at a hotel near PTY if you have a late flight from Sao Paulo-Guarulhos International Airport to Panama City. Pick one of these options and avoid the hassle of a long transfer:

  • Say yes to new adventures by picking up a Tocumen International Airport rental car. Grab a set of wheels from Avis, Dollar or MEX to explore Panama City and beyond.

  • Lock in the best deal by booking your vehicle from Tocumen International Airport around three weeks ahead of your flight from GRU to Panama City.

Marcos A. Gelabert International Airport (PAC)

  • After your flight from Sao Paulo-Guarulhos International Airport to Panama City has arrived, you can get to the city centre in around 5 minutes by car. Central Panama City is roughly 2 kilometres from Marcos A. Gelabert International Airport (PAC).

  • If you're travelling on public transport, it'll take about 25 minutes.

  • You'll find some comfortable places to park your luggage (and yourself) near PAC. Settle in and get cosy after your GRU to Panama City flight at one of these well-located options:

  • The quickest way to reach your destination is with a Marcos A. Gelabert International Airport rental car. Pick up your wheels from Thrifty, Avis or Alamo and make a speedy getaway.

  • Score the best price by reserving your ride from PAC three weeks ahead of time. You can also expect to have a wider range of vehicles.

Panama Pacifico Airport (BLB)

  • Make tracks for the city centre after your flight from Sao Paulo-Guarulhos International Airport to Panama City has landed. Central Panama City is around 16 kilometres from Panama Pacifico Airport (BLB) and takes roughly 20 minutes to reach by cab or ride-share.

  • If you don't want to make your way into the centre, find a hotel near BLB. Check in to one of these stays after your GRU to Panama City flight:

  • Begin your trip without worrying about how to reach your destination with a Panama Pacifico Airport rental car. Find your perfect set of wheels with reliable names here like Sixt, Dollar and Thrifty.

  • Get ahead of the game and reap the rewards. Book your vehicle from BLB one week before your flight from Sao Paulo-Guarulhos International Airport to Panama City for the best rates.

Best time to go to Panama City

  • Carefully consider your trip dates before securing your flight from Sao Paulo-Guarulhos International Airport to Panama City. The city comes alive in peak season, but hotel prices are often higher and attractions can get busy. Plan your trip to Panama City in low season if you prefer a more relaxed vibe.

  • When booking your Sao Paulo-Guarulhos International Airport to Panama City plane ticket, think about the weather you're most comfortable in. March is the warmest month in Panama City, with temperatures ranging from 21ºC (70ºF) to 32ºC (90ºF).

  • Search for cheap tickets from GRU to Panama City in February if you'd rather travel during cooler conditions. Temperatures are at their lowest then, ranging between 22ºC (72ºF) and 31ºC (88ºF) on average.

More about Panama City

  • When it comes to searching for somewhere to lay your head, you'll find the best places to stay in Panama City right here. Explore these options after locking in your flight from Sao Paulo-Guarulhos International Airport to Panama City:

  • Casco Viejo and Panama Canal Museum are just a couple of the top-rated attractions to add to your Panama City to-do list. Keep the adventure rolling by checking out Cinta Costera.

Explore more of Panama

  • You've done Panama City, now it's time to explore other parts of Panama. Journey about 322 kilometres west to David to tick off its popular sights. From Parque Cervantes to Altos del Rio Park and Coquito Hills Park, there's plenty to keep you busy.

  • Around 193 kilometres south-west of Panama City, Santiago de Veraguas is another favourite stop in Panama. Experience the best of this destination with a visit to Santiago the Apostle Cathedral, Santiago de Veraguas, The Church of Jesus Christ of Latter Day Saints and La Placita San Juan De Dios.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.