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226 € Cheap Flights from Mexico City to Panama City Tocumen International

Compare Mexico City to Panama City Tocumen International flight deals

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Flight deals from Mexico City to Panama City Tocumen International Airport

Looking for a cheap last-minute deal or the best return flight from Mexico City to Panama City Tocumen International Airport? If you want to travel next month, return fares start from 226 €. Find the lowest prices on one-way and return tickets right here.
Panama City.226 € per passenger.Departing Wed, 29 Apr, returning Tue, 5 May.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Mexico City Juarez International on Wed, 29 Apr, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 5 May, arriving in Mexico City Juarez International.Price includes taxes and charges.From 226 €, select.
Panama City.226 € per passenger.Departing Fri, 6 Feb, returning Mon, 9 Feb.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Mexico City Juarez International on Fri, 6 Feb, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 9 Feb, arriving in Mexico City Juarez International.Price includes taxes and charges.From 226 €, select.
Panama City.226 € per passenger.Departing Sun, 1 Mar, returning Tue, 3 Mar.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Mexico City Juarez International on Sun, 1 Mar, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 3 Mar, arriving in Mexico City Juarez International.Price includes taxes and charges.From 226 €, select.
Panama City.226 € per passenger.Departing Wed, 28 Jan, returning Sat, 14 Feb.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Mexico City Juarez International on Wed, 28 Jan, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Sat, 14 Feb, arriving in Mexico City Juarez International.Price includes taxes and charges.From 226 €, select.
Panama City.226 € per passenger.Departing Sat, 2 May, returning Sat, 9 May.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Mexico City Juarez International on Sat, 2 May, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Sat, 9 May, arriving in Mexico City Juarez International.Price includes taxes and charges.From 226 €, select.
Panama City.226 € per passenger.Departing Fri, 10 Apr, returning Sun, 19 Apr.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Mexico City Juarez International on Fri, 10 Apr, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Sun, 19 Apr, arriving in Mexico City Juarez International.Price includes taxes and charges.From 226 €, select.
Panama City.226 € per passenger.Departing Wed, 25 Feb, returning Sun, 1 Mar.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Mexico City Juarez International on Wed, 25 Feb, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Sun, 1 Mar, arriving in Mexico City Juarez International.Price includes taxes and charges.From 226 €, select.
Panama City.227 € per passenger.Departing Thu, 26 Mar, returning Wed, 8 Apr.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Mexico City Juarez International on Thu, 26 Mar, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Wed, 8 Apr, arriving in Mexico City Juarez International.Price includes taxes and charges.From 227 €, select.
Panama City.227 € per passenger.Departing Sat, 24 Jan, returning Tue, 27 Jan.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Mexico City Juarez International on Sat, 24 Jan, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 27 Jan, arriving in Mexico City Juarez International.Price includes taxes and charges.From 227 €, select.
Panama City.268 € per passenger.Departing Wed, 4 Mar, returning Wed, 11 Mar.Return flight with Aeromexico.Outbound direct flight with Aeromexico departs from Mexico City Juarez International on Wed, 4 Mar, arriving in Panama City Tocumen International.Inbound direct flight with Aeromexico departs from Panama City Tocumen International on Wed, 11 Mar, arriving in Mexico City Juarez International.Price includes taxes and charges.From 268 €, select.
Panama City.280 € per passenger.Departing Tue, 17 Feb, returning Tue, 3 Mar.Return flight with Aeromexico.Outbound direct flight with Aeromexico departs from Mexico City Juarez International on Tue, 17 Feb, arriving in Panama City Tocumen International.Inbound direct flight with Aeromexico departs from Panama City Tocumen International on Tue, 3 Mar, arriving in Mexico City Juarez International.Price includes taxes and charges.From 280 €, select.
Panama City.280 € per passenger.Departing Mon, 9 Mar, returning Thu, 14 May.Return flight with Aeromexico.Outbound direct flight with Aeromexico departs from Mexico City Juarez International on Mon, 9 Mar, arriving in Panama City Tocumen International.Inbound direct flight with Aeromexico departs from Panama City Tocumen International on Thu, 14 May, arriving in Mexico City Juarez International.Price includes taxes and charges.From 280 €, select.

Find the cheapest month to fly from Mexico City to Panama City Tocumen International

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Mexico City to Panama City Tocumen International flights are currently cheapest in February.
Jan
from 227 €
Feb
from 226 €
Mar
from 226 €
Apr
from 226 €
May
from 226 €
Jun
from 380 €
Jul
from 377 €
Aug
from 377 €
Sep
from 377 €
Oct
from 380 €
Nov
from 377 €
Dec
from 380 €

Direct flights from Mexico City to Panama City Tocumen International

Mexico City to Panama City Tocumen International: Alternative routes

Compare routes from Mexico City to Panama City below. You may find an airport to fly into that's cheaper, faster, or easier than Panama City Tocumen International.

Panama City Paitilla

5km from central Panama City
Closest
from 987 €
Search flights

Balboa

5km from central Panama City
from 441 €
Search flights

Panama City Tocumen International

18km from central Panama City
Cheapest
from 226 €
Search flights

Mexico City to Panama City: Flight information

The things to know before you go.
Cheapest flight found226 €
Cheapest month to flyFebruary
Average flight time3 hrs, 49 mins
Most popular airlineCopa
Average flights per week208

Finding cheap flights from Mexico City to Panama City Tocumen International: Frequently asked questions

The best price we found for a return flight from Mexico City to Panama City Tocumen International is 226 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
3 hours and 48 minutes is the average flight time from Mexico City to Panama City Tocumen International.
Copa, Emirates and Aeromexico fly direct from Mexico City to Panama City Tocumen International.
As of January 2026, there are 104 flights per week flying from Mexico City to Panama City Tocumen International.
The cheapest month to fly from Mexico City to Panama City Tocumen International is usually February.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Mexico City to Panama City Tocumen International Airport on Friday, 6 February 2026.
Yes – the average flight time is 3 hours and 48 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City Tocumen International but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.

Flying from Mexico City to Tocumen International Airport (PTY): What you need to know

  • Mexico City is home to two main airports where you can start your adventure. Check out your options for reserving a flight from Mexico City to Tocumen International Airport (PTY) departing from Benito Juarez International Airport (MEX) or Santa Lucia Air Force Base Airport (NLU).

  • 3 hours 45 minutes is the average travel time for a direct Mexico City to Tocumen International Airport flight.

  • The timezone in Panama City is UTC-5, which is one hour ahead of Mexico City. Tocumen International Airport is located in Panama City.

  • The busiest route is from Benito Juarez International Airport (MEX) to Tocumen International Airport (PTY), with 48 direct weekly services. If you want to be on your way right away, the earliest flight from MEX to PTY is the 1:20am Copa Airlines service. If a later start suits your schedule, the last departure is at 3:35pm with Copa Airlines.

  • Leave enough time to make your flight from Mexico City to PTY. As a rule of thumb, arrive at least two hours before international departures and an hour ahead for domestic flights.

  • In peak travel periods, allow for longer wait times and get there earlier. Aim for at least two hours ahead for domestic flights and as much as four hours for international journeys.

Airports in Mexico City

Benito Juarez International Airport (MEX)

  • You can hop on a direct flight from Mexico City to Tocumen International Airport (PTY) departing from Benito Juarez International Airport (MEX).

  • You can get away on a direct flight from Mexico City to Tocumen International Airport with Copa Airlines. This well-known airline operates departures from MEX.

  • The majority of passengers choose to book seats with Copa Airlines between MEX and PTY.

  • Copa Airlines stands out as the most punctual carrier on this route, with 92.26% of its services landing as scheduled.

  • Consider adding a stopover to find cheap flights from Mexico City to PTY. Simply deselect 'Direct flights only' when searching for departures from Benito Juarez International Airport (MEX). Take a break from travelling at one of these popular airports:

    • Cancun International Airport (CUN)

    • Miguel Hidalgo y Costilla International Airport (GDL)

    • Juan Santamaria International Airport (SJO)

  • The journey from central Mexico City to MEX takes around 55 minutes on public transport. If you drive, ride-share or grab a cab, you'll cover the 8 kilometres in 25 minutes or so, depending on traffic.

  • Looking for a comfortable hotel near Benito Juarez International Airport? If you've booked an early flight from Mexico City to Tocumen International Airport, these accommodation options will put you conveniently close to check-in:

  • 80.91% of flights leaving Benito Juarez International Airport touch down at their destination on schedule. Given its dependable on-time performance, delays are unlikely when taking off from MEX.

Santa Lucia Air Force Base Airport (NLU)

  • Think about kicking off your trip from Santa Lucia Air Force Base Airport (NLU). You can book a direct Mexico City to Tocumen International Airport (PTY) plane ticket from this hub.

  • Catch your direct flight from Mexico City to PTY with Copa Airlines. This is one of the leading carriers flying this route out of NLU.

  • On the NLU to PTY route, Copa Airlines is the go-to airline for most travellers.

  • Book with Copa Airlines if being on time is your priority. Its flights between Santa Lucia Air Force Base Airport and Tocumen International Airport touch down as scheduled 88.0% of the time.

  • Get the most out of your holiday with a stopover on your flight from Mexico City to Tocumen International Airport. Here's where you can connect between Santa Lucia Air Force Base Airport and PTY:

    • Cancun International Airport (CUN)

    • Miguel Hidalgo y Costilla International Airport (GDL)

    • Jose Marti International Airport (HAV)

  • With public transport, you can travel from central Mexico City to NLU in around 1 hour 45 minutes. The airport is roughly 40 kilometres away, and making the trip by car will take approximately 55 minutes.

  • You're off on holiday, so why not spend another night away at a hotel close to Santa Lucia Air Force Base Airport? Before your Mexico City to PTY flight, make yourself comfortable at Verticca Hotel.

  • 67.58% of flights departing Santa Lucia Air Force Base Airport arrive according to schedule.

About Tocumen International Airport (PTY)

Getting from Tocumen International Airport (PTY) to central Panama City

  • Tocumen International Airport to central Panama City is roughly 18 kilometres. If you're renting a car or taking a cab, plan in advance to make your trip as smooth as possible. Journey times will vary based on the time of day and traffic conditions.

  • Travelling on public transport takes around 1 hour 5 minutes.

How to find the cheapest flights from Mexico City to Tocumen International Airport (PTY)

  • 149 € is currently the best price for a one-way ticket from Mexico City to Tocumen International Airport. A return flight starts at 226 €. These prices may change based on availability.

  • Book five months before you travel. Pricing trends show that this is the ideal window for finding cheap flights from Mexico City to PTY.

  • The best month for scoring cheap Mexico City to Tocumen International Airport tickets is October. Use the 'Whole month' tool to compare flight prices, then choose the dates that offer the lowest fares.

  • Never miss a deal on plane tickets from Mexico City to PTY by creating a Price Alert. We'll send you an email or push notification on the app when prices go down.

  • Filters make it easier to dig up a deal for your flight from Mexico City to Tocumen International Airport. Pick the departure times, airlines and number of stops that match your plans. Then sort the results by 'Cheapest' to find the most affordable option fast.

The best time to fly from Mexico City to Tocumen International Airport (PTY)

  • June is when most people book flights from Mexico City to Tocumen International Airport (PTY). Visit Panama City in February for a more low-key escape.

  • Book a Mexico City to PTY plane ticket departing in March if you want to experience the city during its warmest month. Expect temperatures in Panama City to range from 21ºC (70ºF) to 32ºC (90ºF).

  • For cooler conditions, look for a cheap ticket from Mexico City to Tocumen International Airport in February when temperatures are between 22ºC (72ºF) and 31ºC (88ºF).

More about Panama City

  • When it comes to searching for somewhere to lay your head, you'll find the most popular stays in Panama City right here. Check out these hotels as soon as you've locked in your flight from Mexico City to Tocumen International Airport:

  • Casco Viejo and Metropolitan Cathedral (Catedral Metropolitan) are just two of the top-rated attractions to put on your Panama City itinerary. Keep the adventure rolling by checking out Independence Square.

Explore more of Panama

  • You've seen Panama City, now it's time to discover other parts of Panama. Travel around 209 kilometres south-west to Santiago de Veraguas to check off its leading sights. From Santiago the Apostle Cathedral, Santiago de Veraguas to La Placita San Juan De Dios and Salon del Reino de los Testigos de Jehová, you've got a jam-packed schedule ahead.

  • Around 121 kilometres south-west of Panama City, Penonomé is another essential stop in Panama. Get a taste of what this destination has to offer at Charco Verde, Eólico Laudato Sl Park and Miraflores Park.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.