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359 € Cheap Flights from Panama City Tocumen International to Santo Domingo

Compare Panama City Tocumen International to Santo Domingo flight deals

Find the cheapest month or even day of the year to fly to Santo Domingo

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Flight deals from Panama City Tocumen International to Santo Domingo

Looking for a cheap last-minute deal or the best return flight from Panama City Tocumen International to Santo Domingo? Find the lowest prices on one-way and return tickets right here.
Santo Domingo.359 € per passenger.Departing Tue, 16 Sep, returning Tue, 23 Sep.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 16 Sep, arriving in Santo Domingo Las Americas.Inbound indirect flight with Avianca, departs from Santo Domingo Las Americas on Tue, 23 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From 359 €, select.
Santo Domingo.360 € per passenger.Departing Thu, 9 Oct, returning Sat, 18 Oct.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Thu, 9 Oct, arriving in Santo Domingo Las Americas.Inbound indirect flight with Avianca, departs from Santo Domingo Las Americas on Sat, 18 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From 360 €, select.
Santo Domingo.360 € per passenger.Departing Fri, 15 Aug, returning Mon, 25 Aug.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Fri, 15 Aug, arriving in Santo Domingo Las Americas.Inbound indirect flight with Avianca, departs from Santo Domingo Las Americas on Mon, 25 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From 360 €, select.
Santo Domingo.360 € per passenger.Departing Fri, 21 Nov, returning Sun, 23 Nov.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Fri, 21 Nov, arriving in Santo Domingo Las Americas.Inbound indirect flight with Avianca, departs from Santo Domingo Las Americas on Sun, 23 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From 360 €, select.
Santo Domingo.360 € per passenger.Departing Thu, 22 Jan, returning Mon, 26 Jan.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Thu, 22 Jan, arriving in Santo Domingo Las Americas.Inbound indirect flight with Avianca, departs from Santo Domingo Las Americas on Mon, 26 Jan, arriving in Panama City Tocumen International.Price includes taxes and charges.From 360 €, select.
Santo Domingo.361 € per passenger.Departing Thu, 4 Dec, returning Mon, 8 Dec.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Thu, 4 Dec, arriving in Santo Domingo Las Americas.Inbound indirect flight with Avianca, departs from Santo Domingo Las Americas on Mon, 8 Dec, arriving in Panama City Tocumen International.Price includes taxes and charges.From 361 €, select.
Santo Domingo.361 € per passenger.Departing Fri, 28 Nov, returning Tue, 2 Dec.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Fri, 28 Nov, arriving in Santo Domingo Las Americas.Inbound indirect flight with Avianca, departs from Santo Domingo Las Americas on Tue, 2 Dec, arriving in Panama City Tocumen International.Price includes taxes and charges.From 361 €, select.
Santo Domingo.361 € per passenger.Departing Fri, 31 Oct, returning Wed, 5 Nov.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Fri, 31 Oct, arriving in Santo Domingo Las Americas.Inbound indirect flight with Avianca, departs from Santo Domingo Las Americas on Wed, 5 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From 361 €, select.

Find the cheapest month to fly from Panama City Tocumen International to Santo Domingo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City Tocumen International to Santo Domingo flights are currently cheapest in September.
Aug
from 360 €
Sep
from 359 €
Oct
from 360 €
Nov
from 360 €
Dec
from 361 €
Jan
from 360 €
Feb
from 361 €
Mar
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Apr
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May
from 389 €
Jun
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Jul
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Direct flights from Panama City Tocumen International to Santo Domingo

Alternative Panama City Tocumen International to Santo Domingo routes

Looking for the cheapest, fastest or easiest route from Panama City Tocumen International to Santo Domingo? You could fly into the following airports instead.

Panama City to Santo Domingo: Flight information

The things to know before you go.
Cheapest flight found359 €
Cheapest month to flySeptember
Average flight time2 hrs, 29 mins
Most popular airlineCopa
Average flights per week54

Finding cheap flights from Panama City Tocumen International to Santo Domingo: Frequently asked questions

There are 3 airports in Santo Domingo: La Isabela International, Santo Domingo Las Americas and Samana.
The best price we found for a return flight from Panama City Tocumen International to Santo Domingo is 359 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
2 hours and 29 minutes is the average flight time from Panama City Tocumen International to Santo Domingo.
Copa, KLM and Air France fly direct from Panama City Tocumen International to Santo Domingo.
As of August 2025, there are 54 flights per week flying from Panama City Tocumen International to Santo Domingo.
The cheapest month to fly from Panama City Tocumen International to Santo Domingo is usually September.
If you're flying from Panama City Tocumen International Airport, the cheapest airport near Santo Domingo is Santo Domingo Las Americas – which is 23.4 km away from the centre of Santo Domingo. We've found flights into this airport from 359 €.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Panama City Tocumen International Airport to Santo Domingo on Tuesday, 16 September 2025.
Yes – the average flight time is 2 hours and 29 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santo Domingo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santo Domingo is around 40 days in advance, so don’t leave your flight to the last minute.
In August, the average temperature is usually around 28°C. August is typically the warmest month in Santo Domingo, when it usually averages around 31°C. You can expect the least rain in March. The coldest month is January, with temperatures averaging 21°C. The rainiest month is September.
Currently, Avianca and Copa offer the cheapest flight tickets to Santo Domingo.

Travelling from Tocumen International Airport (PTY) to Santo Domingo: what you need to know

  • The average duration of a direct flight from Tocumen International Airport to Santo Domingo is 2 hours 35 minutes.

  • Tocumen International Airport is located in Panama City. Based in the UTC-4 timezone, Santo Domingo is one hour ahead of Panama City.

  • With 29 weekly flights between the two airports, Tocumen International Airport (PTY) to Las Americas International Airport (SDQ) is the most popular route. Copa Airlines operates the earliest flight at 07:18. If you prefer to make the most of your day before flying, the latest departure from PTY to SDQ is with Copa Airlines at 23:13.

  • Give yourself enough time to make your PTY to Santo Domingo flight. A good rule of thumb is to arrive two hours before international departures and an hour ahead for domestic flights.

  • Planning to travel during a peak period like a bank holiday? Expect longer queues at security and check-in. For peace of mind, arrive up to four hours before international flights and two hours before domestic departures.

  • Start your trip at PTY and fly straight to Las Americas International Airport (SDQ). That's where you can expect to land when searching for Tocumen International Airport to Santo Domingo tickets.

  • Copa Airlines is a popular airline that operates direct flights from Tocumen International Airport to Santo Domingo.

  • We make it simple to book plane tickets from PTY to Santo Domingo with a stopover. To see all the options, uncheck 'Direct flights only.' Next, choose a flight offering a stop long enough to see the sights of the city of your choice. Well-traveled stopover hubs include:

    • Miami International Airport (MIA)

    • Luis Munoz Marin International Airport (SJU)

    • Reina Beatrix International Airport (AUA)

  • Located around 18 kilometres from the centre of Panama City, PTY can be reached in about 20 minutes by car, depending on traffic. The journey on public transport will take roughly 1 hour 5 minutes.

  • Want an easy start to your journey? Stay near PTY. Whether you've booked an early flight from Tocumen International Airport to Santo Domingo or just don't like being rushed, these hotels put convenience first:

  • Tocumen International Airport scores high marks for its on-time performance. 86.03% of flights that take off from PTY reach their destination without delay.

How to find the cheapest flights from Tocumen International Airport (PTY) to Santo Domingo

  • 197 € is currently the best price for a one-way Tocumen International Airport to Santo Domingo flight. Return plane tickets start from 359 €. These fares may change based on availability.

  • Booking in advance is often the key to finding a cheap flight from PTY to Santo Domingo. Prices tend to rise as demand increases, so the closer you get to departure, the more it could cost you.

  • Landing cheap tickets from Tocumen International Airport to Santo Domingo is more likely if you can be flexible with your dates. Try using the 'Whole month' tool to access the lowest fares across the month and walk away with an incredible deal.

  • Never miss a deal on cheap flights from PTY to Santo Domingo by setting up a Price Alert. We'll send you an email or notification on the app when fares go down.

  • Find a cheap flight from Tocumen International Airport to Santo Domingo with the help of our filters. Select your ideal duration, departure time and airlines, then sort the results by 'Cheapest' for the best deals.

Airports in Santo Domingo

Las Americas International Airport (SDQ)

  • Las Americas International Airport (SDQ) to central Santo Domingo takes about 30 minutes by car. The centre is roughly 32 kilometres away.

  • The last thing you need is a lengthy journey to your hotel if you're getting in late on a flight from Tocumen International Airport to Santo Domingo. Check in to one of these accommodation options near SDQ instead:

  • Hit the road running by picking up a Las Americas International Airport rental car. Grab your wheels from Final Rentals, FlexWays or INFINITY RENT and experience the lesser-explored corners of Santo Domingo and beyond.

  • Booking your ride from Las Americas International Airport around one week in advance of your flight from PTY to Santo Domingo can help you get the lowest rate.

Dr. Joaquin Balaguer International Airport (JBQ)

  • Dr. Joaquin Balaguer International Airport (JBQ) is about 19 kilometres from central Santo Domingo. Once you've hopped off your flight from Tocumen International Airport to Santo Domingo, it'll take you around 25 minutes to reach the heart of the city in a ride-share or cab.

  • Micro Hotel Condo Suites is a comfortable accommodation option within a short drive of JBQ. Check in here after your PTY to Santo Domingo flight and then put up the 'Do not disturb' sign to enjoy some uninterrupted rest.

  • Line up the perfect playlist and hit the road in a Dr. Joaquin Balaguer International Airport rental car. Pick up a set of wheels from FlexWays and set off on your adventure right away.

  • Avoid filling out forms at the rental desk by having everything prearranged. Reserve your ride from JBQ ahead of time so you can simply pick up the keys and get on your way.

Best time to go to Santo Domingo

  • Before booking your flights from Tocumen International Airport to Santo Domingo, consider which time of year works best for you. High season in Santo Domingo offers a bustling atmosphere and plenty of activities, while the off-season means you'll get cheaper deals on hotels and fewer crowds.

  • Before booking a Tocumen International Airport to Santo Domingo plane ticket, think about the kind of weather you prefer. September is the warmest month in Santo Domingo, with temperatures ranging from 23ºC (73ºF) to 33ºC (91ºF).

  • Search for cheap tickets from PTY to Santo Domingo in February if you want to travel in cooler conditions. Temperatures are at their lowest then, ranging between 19ºC (66ºF) and 29ºC (84ºF) on average.

More about Santo Domingo

  • Start your Santo Domingo trip right by choosing the perfect place to stay. As soon as you've booked your flight from Tocumen International Airport to Santo Domingo, explore our range of hotels including:

  • National Palace and Alcazar de Colon are just two of the leading attractions to add to your Santo Domingo itinerary. Continue your sightseeing adventures at Basilica Cathedral of Santa Maria la Menor.

Explore more of Dominican Republic

  • You've seen Santo Domingo, now it's time to discover other corners of Dominican Republic. Journey about 105 kilometres east to La Romana to tick off its leading sights. From Dye Fore Golf Course of Casa de Campo to Minitas Beach and La Estrella Park, you'll have a packed itinerary ahead.

  • Around 161 kilometres north-west of Santo Domingo, Puerto Plata is another favourite stop in Dominican Republic. Start your sightseeing at Fortaleza San Felipe, Teleferico Puerto Plata Cable Car and Malecon Puerto Plata.

Plan the rest of your trip from Panama City to Santo Domingo

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.