Cheap Flights from Knoxville to South Carolina from 199 € Return

Flight deals from Knoxville to South Carolina

Looking for cheap tickets from Knoxville to South Carolina, or a last-minute trip? Find the lowest prices on one-way and return tickets right here.

Myrtle Beach.199 € per passenger.Departing Tue, 8 Jul, returning Tue, 15 Jul.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Tue, 8 Jul, arriving in Myrtle Beach International .Inbound indirect flight with Delta, departs from Myrtle Beach International on Tue, 15 Jul, arriving in Knoxville.Price includes taxes and charges.From 199 €, select.

Charleston.312 € per passenger.Departing Thu, 11 Dec, returning Tue, 16 Dec.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Thu, 11 Dec, arriving in Charleston.Inbound indirect flight with Delta, departs from Charleston on Tue, 16 Dec, arriving in Knoxville.Price includes taxes and charges.From 312 €, select.

Greenville.321 € per passenger.Departing Mon, 1 Dec, returning Sat, 6 Dec.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Mon, 1 Dec, arriving in Greenville-Spartanburg.Inbound indirect flight with Delta, departs from Greenville-Spartanburg on Sat, 6 Dec, arriving in Knoxville.Price includes taxes and charges.From 321 €, select.

Columbia.456 € per passenger.Departing Sat, 28 Jun, returning Wed, 2 Jul.Return flight with Delta.Outbound indirect flight with Delta, departs from Knoxville on Sat, 28 Jun, arriving in Columbia Metropolitan.Inbound indirect flight with Delta, departs from Columbia Metropolitan on Wed, 2 Jul, arriving in Knoxville.Price includes taxes and charges.From 456 €, select.

Flying from Knoxville to South Carolina

Arm yourself with these facts on the fly.

Cheapest flight found	199 €, Myrtle Beach
Cheapest month to fly	July
Cheapest airport to fly from	Knoxville

How to find cheap flights from Knoxville to South Carolina

We've compared the best online travel agents and flight providers on the internet to find the cheapest plane tickets from Knoxville to South Carolina. Other savvy travellers recently found return flights from 199 € and one-way tickets from 199 € one-way. Ready to join them? Here are a few tips to help you do it the smart way.

Fly from Knoxville into Myrtle Beach

At the moment, the lowest priced flight tickets to South Carolina are from Knoxville Airport to Myrtle Beach International Airport.

Fly in July

We crunched the flight calendar and found the cheapest time to fly from Knoxville to South Carolina is currently July.

Fly on a Friday

From our data, we can see that Friday seems to be the cheapest time to fly from Knoxville to South Carolina.

Flex your dates for the best rates

If you’re flexible on your departure dates, you can use Skyscanner's whole month tool to find the cheapest day of the year to fly from Knoxville to anywhere you choose in South Carolina.

Watch as fares rise and fall

With Price Alerts, we'll let you know when flight prices from Knoxville to South Carolina go up or down so you can book when the time is just right.

Relax – these are fee-free flight tickets

With us, there are no added fees – the Knoxville to South Carolina flight price you see when you search with us is what you pay to the provider.

Frequently asked questions

What's the average Knoxville to South Carolina flight price?

We looked at all of the upcoming return flights from Knoxville to South Carolina we could find over the next 12 months. It looks like 199 € is the best price. This is good, compared to the average South Carolina ticket price of 351 €.

What is the cheapest month to fly from Knoxville to South Carolina?

The cheapest month to fly from Knoxville to Columbia Metropolitan Airport is usually June. The cheapest month to fly from Knoxville to Greenville-Spartanburg Airport is usually December. The cheapest month to fly from Knoxville to Charleston Airport is usually December. And the cheapest month to fly from Knoxville to Myrtle Beach International Airport is usually July.

Which upcoming date is cheapest to fly from Knoxville to South Carolina on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Knoxville to South Carolina on Tuesday, 8 July 2025.

Are there any direct flights from Knoxville to South Carolina?

Currently, there aren't any direct flights from Knoxville to South Carolina, but you can still fly with a stopover.

If I'm flying from Knoxville, where in South Carolina is cheapest to fly into?

If you're flying from Knoxville, the cheapest city in South Carolina to fly into is Myrtle Beach. The cheapest airport serving Myrtle Beach at the moment is Myrtle Beach International .

Flights from Knoxville to South Carolina