Cheap Flights from Buffalo to South Carolina from 169 € Return

Flight deals from Buffalo to South Carolina

Looking for cheap tickets from Buffalo to South Carolina, or a last-minute trip? Find the lowest prices on one-way and return tickets right here.

Charleston.169 € per passenger.Departing Sun, 12 Apr, returning Thu, 16 Apr.Return flight with Delta.Outbound indirect flight with Delta, departs from Buffalo Niagara on Sun, 12 Apr, arriving in Charleston.Inbound indirect flight with Delta, departs from Charleston on Thu, 16 Apr, arriving in Buffalo Niagara.Price includes taxes and charges.From 169 €, select.

Myrtle Beach.199 € per passenger.Departing Fri, 27 Feb, returning Mon, 2 Mar.Return flight with Frontier Airlines and Spirit Airlines.Outbound indirect flight with Frontier Airlines, departs from Buffalo Niagara on Fri, 27 Feb, arriving in Myrtle Beach International .Inbound indirect flight with Spirit Airlines, departs from Myrtle Beach International on Mon, 2 Mar, arriving in Buffalo Niagara.Price includes taxes and charges.From 199 €, select.

Greenville.232 € per passenger.Departing Thu, 19 Feb, returning Sun, 1 Mar.Return flight with Frontier Airlines and Allegiant Air.Outbound indirect flight with Frontier Airlines, departs from Buffalo Niagara on Thu, 19 Feb, arriving in Greenville-Spartanburg.Inbound indirect flight with Allegiant Air, departs from Greenville-Spartanburg on Sun, 1 Mar, arriving in Buffalo Niagara.Price includes taxes and charges.From 232 €, select.

Columbia.254 € per passenger.Departing Thu, 28 May, returning Sun, 31 May.Return flight with Delta.Outbound indirect flight with Delta, departs from Buffalo Niagara on Thu, 28 May, arriving in Columbia Metropolitan.Inbound indirect flight with Delta, departs from Columbia Metropolitan on Sun, 31 May, arriving in Buffalo Niagara.Price includes taxes and charges.From 254 €, select.

Hilton Head Island.568 € per passenger.Departing Fri, 15 May, returning Tue, 19 May.Return flight with Delta.Outbound indirect flight with Delta, departs from Buffalo Niagara on Fri, 15 May, arriving in Hilton Head.Inbound indirect flight with Delta, departs from Hilton Head on Tue, 19 May, arriving in Buffalo Niagara.Price includes taxes and charges.From 568 €, select.

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Flying from Buffalo to South Carolina

Arm yourself with these facts on the fly.

Cheapest flight found	169 €
Cheapest month to fly	April
Cheapest airport to fly from	Buffalo Niagara

How to find cheap flights from Buffalo to South Carolina

We've compared the best online travel agents and flight providers on the internet to find the cheapest plane tickets from Buffalo to South Carolina. Other savvy travellers recently found return flights from 169 € and one-way tickets from 84 € one-way. Ready to join them? Here are a few tips to help you do it the smart way.

Fly from Buffalo Niagara into Charleston

At the moment, the lowest priced flight tickets to South Carolina are from Buffalo Niagara Airport to Charleston Airport.

Fly in April

We crunched the flight calendar and found the cheapest time to fly from Buffalo to South Carolina is currently April.

Flex your dates for the best rates

If you’re flexible on your departure dates, you can use Skyscanner's whole month tool to find the cheapest day of the year to fly from Buffalo to anywhere you choose in South Carolina.

Watch as fares rise and fall

With Price Alerts, we'll let you know when flight prices from Buffalo to South Carolina go up or down so you can book when the time is just right.

Relax – these are fee-free flight tickets

With us, there are no added fees – the South Carolina to South Carolina flight price you see when you search with us is what you pay to the provider.

Frequently asked questions

What's the average Buffalo to South Carolina flight price?

We looked at all of the upcoming return flights from Buffalo to South Carolina we could find over the next 12 months. It looks like 169 € is the best price. This is good, compared to the average South Carolina ticket price of 284 €.

What is the cheapest month to fly from Buffalo to South Carolina?

The cheapest month to fly from Buffalo to Hilton Head Airport is usually May. The cheapest month to fly from Buffalo to Myrtle Beach International Airport is usually February. The cheapest month to fly from Buffalo to Charleston Airport is usually April. And the cheapest month to fly from Buffalo to Columbia Metropolitan Airport is usually May.

Which upcoming date is cheapest to fly from Buffalo to South Carolina on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Buffalo to South Carolina on Sunday, 12 April 2026.

Are there any direct flights from Buffalo to South Carolina?

Currently, there aren't any direct flights from Buffalo to South Carolina, but you can still fly with a stopover.

If I'm flying from Buffalo, where in South Carolina is cheapest to fly into?

If you're flying from Buffalo, the cheapest city in South Carolina to fly into is Charleston. The cheapest airport serving Charleston at the moment is Charleston.