Twentyone Hotel

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Fast facts

Check in from:
15:00
Check out before:
11:00
Pets
Pets not allowed

Amenities

Wi-Fi
Parking
Air conditioning
Airport shuttle
Fitness centre
Front desk 24 hour

More about Twentyone Hotel

Twentyone Hotel

The Twentyone is a modern boutique hotel on Via Cola di Rienzo, one of Rome's best shopping streets. Castel Sant'Angelo and the historic centre are just a pleasant 10-minute walk away.

Reviews from
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Mentioned by travellers
Group traveller

Comment: 17 Aug 2026

Stayed in: Aug 2026

Beautiful experience

3 days to celebrate an important birthday, very kind staff, they even surprised our friend who turned 50 without us saying anything. Spotless facility.

Hotel response

Comment: 25 Aug 2026

Gentile Ester,
Grazie di cuore per aver condiviso una recensione così speciale!
Sapere che avete scelto la nostra struttura per festeggiare un traguardo importante come un 50° compleanno è per noi un grandissimo onore.
Ci fa davvero felici sapere che la piccola sorpresa a sorpresa per la vostra amica sia stata gradita e che abbiate apprezzato la pulizia e l'attenzione del nostro staff. Rinnoviamo i nostri migliori auguri alla festeggiata e vi aspettiamo a braccia aperte per le vostre prossime occasioni speciali!
Family traveller

Comment: 15 Aug 2026

Stayed in: Aug 2026

Don't book this hotel- We had a pest issue at our room!!

My family and I stayed last wee in this hotel. Right after we went to bed, tick Bugs started coming out of my 3 year old's bed. If bitten, these Bugs can pose serious health risks especially to a little chile. After calling Management, they committed to support any claim Made through our Booking channel. However, they denied any responsibility and failed to reach to a settlement. Not only do they have TERRIBLE higiene standards, they surely did not display any ethical behavior and Made themselves accountable. We do not recommend this hotel at all. For transparency, I am attaching the photographic evidence sent to our Booking platform.

Hotel response

Comment: 25 Aug 2026

Dear Dianas,
We strictly reject these allegations and the inaccurate portrayal of our establishment. Following your report, our property immediately underwent a thorough inspection by a certified, independent pest control agency. The professional evaluation confirmed zero presence of bed bugs or ticks anywhere in the room.
We maintain rigorous, documented sanitation protocols and certified inspections to ensure the highest hygiene standards. Furthermore, all claims processed through third-party booking channels are reviewed using verified professional findings rather than unsubstantiated assertions. We act with complete integrity, base our decisions on factual evidence, and firmly stand by the safety and cleanliness of our hotel."
Family traveller

Comment: 15 Aug 2026

Stayed in: Aug 2026

Terrible experience. TICK bugs coming out of matress!!

My wife recently wrote a review but I thought it is worthwhile underscoring our terrible experience at this hotel. We stayed here last week and had tick bugs coming out of my daughters mattress into the wall. We had to leave the hotel due to safety reasons and submitted a refund claim, which the hotel denied after having their staff and one of Management team members present during the incident. Very disappointing on the cleaning/pest control standards and on their ethical posture in denying their accountability.

Hotel response

Comment: 25 Aug 2026

Dear Juan,
We strictly reject these allegations and the inaccurate portrayal of our establishment. Following your report, our property immediately underwent a thorough inspection by a certified, independent pest control agency. The professional evaluation confirmed zero presence of bed bugs or ticks anywhere in the room. We maintain rigorous, documented sanitation protocols and certified inspections to ensure the highest hygiene standards. Furthermore, all claims processed through third-party booking channels are reviewed using verified professional findings rather than unsubstantiated assertions. We act with complete integrity, base our decisions on factual evidence, and firmly stand by the safety and cleanliness of our hotel."
Family traveller

Comment: 6 Aug 2026

Stayed in: Aug 2026

Do not stay here unless you like a very hard mattress.

I am currently on night one of a two night stay and I can tell you, the beds are the most uncomfortable mattresses I have ever felt and I travel a fair amount.
I'm not sure I'll be able to walk tomorrow.
Other than that, rooms are decent and clean.

Hotel response

Comment: 7 Aug 2026

Dear Guest,
Thank you for sharing your feedback. We are sorry to hear that you find our mattresses uncomfortable.
Mattress firmness is a matter of personal preference, and while many of our guests appreciate the support of our firm bedding, we recognize that it may not suit everyone's individual sleeping style. However, we take guest comfort seriously—had you brought this to our front desk's attention during your first night, our team would have gladly provided a mattress topper or explored alternative room options to make your remaining stay more comfortable.
We appreciate your positive comments regarding the cleanliness and standard of our rooms, and we hope the remainder of your stay in Rome is pleasant.
kind regards
Solo traveller

Comment: 29 Jul 2026

Stayed in: Jul 2026

Excellent value for money!

Excellent location, hospitality, comfort, and high-level quality. Panoramic restaurant with excellent food and wines. I will return ✨

Hotel response

Comment: 30 Jul 2026

Gentile Mario,
la ringraziamo di cuore per questa splendida recensione!
Sapere che ha apprezzato la nostra accoglienza, il comfort della struttura e la qualità dei nostri servizi ci riempie di orgoglio. Il nostro ristorante panoramico è pensato proprio per regalare momenti speciali, ed è una gioia sapere che il cibo e i vini siano stati all'altezza delle sue aspettative.
Non vediamo l'ora di riaccoglierla per un altro soggiorno indimenticabile! ✨
Cordiali saluti

Excellent location

4.5

Via Cola Di Rienzo 23, Municipio Roma I, Rome, 00192, Italy|2.92 km from city centre

Check in and check out

Check in from:

15:00

Check out before:

11:00

Good to know

Pets

Pets not allowed

Extra beds

Please contact the hotel for details about adding extra beds.

Twentyone Hotel: FAQs

Twentyone Hotel is 2.9 km away from Rome city centre.
Twentyone Hotel is in Rome, Italy and is 2.9 km away from Rome city centre.
Yes, there is parking available at Twentyone Hotel.
Yes, Twentyone Hotel does have a restaurant.