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293 € Cheap Flights from Greenville-Spartanburg to San Diego

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Flight deals from Greenville-Spartanburg Airport to San Diego

Looking for a cheap last-minute deal or the best return flight from Greenville-Spartanburg Airport to San Diego? If you want to travel next month, return fares start from 328 €. Find the lowest prices on one-way and return tickets right here.
San Diego.293 € per passenger.Departing Fri, 27 Feb, returning Thu, 5 Mar.Return flight with Breeze Airways and Frontier Airlines.Outbound indirect flight with Breeze Airways, departs from Greenville-Spartanburg on Fri, 27 Feb, arriving in San Diego International.Inbound indirect flight with Frontier Airlines, departs from San Diego International on Thu, 5 Mar, arriving in Greenville-Spartanburg.Price includes taxes and charges.From 293 €, select.
San Diego.313 € per passenger.Departing Wed, 4 Mar, returning Wed, 11 Mar.Return flight with Delta.Outbound indirect flight with Delta, departs from Greenville-Spartanburg on Wed, 4 Mar, arriving in San Diego International.Inbound indirect flight with Delta, departs from San Diego International on Wed, 11 Mar, arriving in Greenville-Spartanburg.Price includes taxes and charges.From 313 €, select.
San Diego.324 € per passenger.Departing Thu, 26 Mar, returning Wed, 1 Apr.Return flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Greenville-Spartanburg on Thu, 26 Mar, arriving in San Diego International.Inbound indirect flight with Southwest Airlines, departs from San Diego International on Wed, 1 Apr, arriving in Greenville-Spartanburg.Price includes taxes and charges.From 324 €, select.
San Diego.328 € per passenger.Departing Thu, 26 Feb, returning Sat, 28 Feb.Return flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Greenville-Spartanburg on Thu, 26 Feb, arriving in San Diego International.Inbound indirect flight with Southwest Airlines, departs from San Diego International on Sat, 28 Feb, arriving in Greenville-Spartanburg.Price includes taxes and charges.From 328 €, select.
San Diego.377 € per passenger.Departing Wed, 15 Jul, returning Wed, 22 Jul.Return flight with United.Outbound indirect flight with United, departs from Greenville-Spartanburg on Wed, 15 Jul, arriving in San Diego International.Inbound indirect flight with United, departs from San Diego International on Wed, 22 Jul, arriving in Greenville-Spartanburg.Price includes taxes and charges.From 377 €, select.
San Diego.380 € per passenger.Departing Fri, 17 Apr, returning Sun, 19 Apr.Return flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Greenville-Spartanburg on Fri, 17 Apr, arriving in San Diego International.Inbound indirect flight with Southwest Airlines, departs from San Diego International on Sun, 19 Apr, arriving in Greenville-Spartanburg.Price includes taxes and charges.From 380 €, select.
San Diego.381 € per passenger.Departing Fri, 26 Jun, returning Sun, 28 Jun.Return flight with Delta.Outbound indirect flight with Delta, departs from Greenville-Spartanburg on Fri, 26 Jun, arriving in San Diego International.Inbound indirect flight with Delta, departs from San Diego International on Sun, 28 Jun, arriving in Greenville-Spartanburg.Price includes taxes and charges.From 381 €, select.
San Diego.381 € per passenger.Departing Fri, 7 Aug, returning Mon, 10 Aug.Return flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Greenville-Spartanburg on Fri, 7 Aug, arriving in San Diego International.Inbound indirect flight with Southwest Airlines, departs from San Diego International on Mon, 10 Aug, arriving in Greenville-Spartanburg.Price includes taxes and charges.From 381 €, select.
San Diego.389 € per passenger.Departing Wed, 24 Jun, returning Wed, 1 Jul.Return flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Greenville-Spartanburg on Wed, 24 Jun, arriving in San Diego International.Inbound indirect flight with Southwest Airlines, departs from San Diego International on Wed, 1 Jul, arriving in Greenville-Spartanburg.Price includes taxes and charges.From 389 €, select.
San Diego.495 € per passenger.Departing Mon, 26 Jan, returning Mon, 2 Feb.Return flight with Breeze Airways and Frontier Airlines.Outbound indirect flight with Breeze Airways, departs from Greenville-Spartanburg on Mon, 26 Jan, arriving in San Diego International.Inbound indirect flight with Frontier Airlines, departs from San Diego International on Mon, 2 Feb, arriving in Greenville-Spartanburg.Price includes taxes and charges.From 495 €, select.

Find the cheapest month to fly from Greenville-Spartanburg to San Diego

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Greenville-Spartanburg to San Diego flights are currently cheapest in March.
Jan
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Feb
from 328 €
Mar
from 313 €
Apr
from 380 €
May
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Jun
from 381 €
Jul
from 377 €
Aug
from 381 €
Sep
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Oct
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Nov
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Dec
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Alternative Greenville-Spartanburg to San Diego routes

Looking for the cheapest, fastest or easiest route from Greenville-Spartanburg to San Diego? You could fly into the following airports instead.

San Diego International

4km from central San Diego
ClosestCheapest
from 293 €
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McClellan-Palomar

48km from central San Diego
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Greenville to San Diego: Flight information

The things to know before you go.
Cheapest flight found293 €
Cheapest month to flyFebruary

Finding cheap flights from Greenville-Spartanburg to San Diego: Frequently asked questions

There are 2 airports in San Diego: San Diego International and McClellan-Palomar.
The best price we found for a return flight from Greenville-Spartanburg to San Diego is 293 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Greenville-Spartanburg to San Diego. But we found flights with one or more stops from 293 €.
As of January 2026, there are no flights flying from Greenville-Spartanburg to San Diego.
The cheapest month to fly from Greenville-Spartanburg to San Diego is usually February.
If you're flying from Greenville-Spartanburg Airport, the cheapest airport near San Diego is San Diego International – which is 4.1 km away from the centre of San Diego. We've found flights into this airport from 293 €.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Greenville-Spartanburg Airport to San Diego on Friday, 27 February 2026.
No airlines currently offer direct flights between Greenville-Spartanburg Airport and San Diego. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to San Diego but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to San Diego is around 40 days in advance, so don’t leave your flight to the last minute.
In January, the average temperature is usually around 13°C. August is typically the warmest month in San Diego, when it usually averages around 28°C. You can expect the least rain in June. The coldest month is December, with temperatures averaging 10°C. The rainiest month is February.
Currently, Breeze Airways offers the cheapest flight tickets to San Diego.

Travelling from Greenville-Spartanburg International Airport (GSP) to San Diego: what you need to know

  • Greenville-Spartanburg International Airport is located in Greenville. Based in the UTC-7 timezone, San Diego is three hours behind Greenville.

  • For a smooth journey, turn up at the airport two hours ahead of international flights and one hour before domestic departures. This will give you plenty of time to board your GSP to San Diego flight.

  • Travelling during a peak time like a bank holiday? Expect longer lines at check-in and security. To give yourself peace of mind, arrive up to four hours before international flights and two hours before domestic departures.

  • To get to GSP from central Greenville, it'll take about 20 minutes if you're going by car. It's roughly 16 kilometres from the airport to the city centre.

  • Catching an early flight from Greenville-Spartanburg International Airport to San Diego? Avoid the stress of rushing to the terminal (and get some extra shut-eye) by choosing one of these stays near GSP:

  • Of all flights departing from Greenville-Spartanburg International Airport, 79.7% arrive on time at their destination.

  • You'll find GSP at 2000 GPS Drive, Suite 1.

How to find the cheapest flights from Greenville-Spartanburg International Airport (GSP) to San Diego

  • 131 € is currently the best price for a one-way Greenville-Spartanburg International Airport to San Diego flight. Return plane tickets start from 293 €. These prices may change based on demand and availability.

  • Booking early is often the key to scoring a cheap flight from GSP to San Diego. Fares tend to rise as demand increases, so the closer you get to departure, the more it could cost you.

  • If you're flexible with your travel plans, make the most of the 'Whole month' search tool. It'll show you the cheapest price across every month when looking for your Greenville-Spartanburg International Airport to San Diego ticket.

  • There's no need to check back constantly to see if fares have dropped when you set up a Price Alert. We'll let you know the moment there's an updated deal for cheap flights from GSP to San Diego.

  • Tailor your trip with filters. Pick your ideal arrival and departure times, total journey duration and airlines. You can also sort your results by 'Cheapest,' 'Best' or 'Fastest' flights from Greenville-Spartanburg International Airport to San Diego.

Airports in San Diego

San Diego International Airport (SAN)

  • San Diego International Airport (SAN) to central San Diego takes about 10 minutes to reach by car. The centre is roughly 5 kilometres away.

  • Getting to the centre on public transport will take you around 20 minutes.

  • The last thing you want is a lengthy journey to your hotel if you're arriving on a late flight from Greenville-Spartanburg International Airport to San Diego. Check in to one of these accommodation options near SAN instead:

  • Grab a San Diego International Airport rental car and discover San Diego and beyond with your own wheels. Thrifty, Dollar and Budget are leading providers you can book with here.

  • Lock in the best possible rate by booking your vehicle from San Diego International Airport about two weeks ahead of your flight from GSP to San Diego.

  • The address for SAN is N Harbour Dr.

McClellan-Palomar Airport (CLD)

  • The centre of San Diego is located around 56 kilometres from McClellan-Palomar Airport (CLD). Once your flight from Greenville-Spartanburg International Airport to San Diego has touched down and you've made your way out of the airport, the drive should take about 40 minutes.

  • If you choose to travel on public transport, you'll reach the centre in 2 hours 15 minutes or so.

  • Following your GSP to San Diego flight, rest your head at a hotel near CLD. These are some great options that'll help you get into relaxation mode:

  • The quickest way to reach your destination is with a McClellan-Palomar Airport rental car. Grab your wheels from Budget, Hertz or Avis and hit the road in a heartbeat.

  • Get the vehicle you actually want, not just what's available, by reserving your ride from CLD ahead of your arrival. You can also avoid paying more than you need to, especially when demand is high.

Best time to go to San Diego

  • Carefully consider your trip dates before locking in your flight from Greenville-Spartanburg International Airport to San Diego. The city buzzes during high season, but rates are often higher and major attractions can get busy. Go to San Diego in the off-season if you prefer a more relaxed vibe.

  • Before booking a Greenville-Spartanburg International Airport to San Diego plane ticket, think about the type of weather you enjoy. August is the warmest month in San Diego, with temperatures ranging from 17ºC (63ºF) to 28ºC (82ºF).

  • If you'd rather travel in cooler conditions, look for a cheap ticket from GSP to San Diego in February when temperatures average between 7ºC (45ºF) and 23ºC (73ºF).

More about San Diego

  • When it comes to searching for somewhere to lay your head, you'll find the most popular stays in San Diego right here. Browse these options once you've locked in your flight from Greenville-Spartanburg International Airport to San Diego:

  • USS Midway Museum and San Diego Zoo are just the start of the popular attractions to put on your San Diego to-do list. Keep the adventure rolling by checking out SeaWorld San Diego.

Explore more of United States

  • You've seen San Diego, now it's time to explore other corners of United States. Travel around 177 kilometres north-west to Los Angeles to tick off its must-visit sights. From Griffith Observatory to The Broad and La Brea Tar Pits & Museum, you've got a jam-packed schedule ahead.

  • Around 483 kilometres east of San Diego, Phoenix is another essential stop in United States. Start your sightseeing at Desert Botanical Garden, Heard Museum and Papago Park.

Plan the rest of your trip from Greenville to San Diego

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.