366 € Cheap Flights from Santa Ana John Wayne to Buffalo Niagara

Compare Santa Ana John Wayne to Buffalo Niagara flight deals

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Find the cheapest month to fly from Santa Ana John Wayne to Buffalo Niagara

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Santa Ana John Wayne to Buffalo Niagara flights are currently cheapest in October.

Santa Ana John Wayne to Buffalo Niagara: Alternative routes

Compare routes from Santa Ana John Wayne to Buffalo below. You may find an airport to fly into that's cheaper, faster, or easier than Buffalo Niagara.

Santa Ana to Buffalo: Flight information

The things to know before you go.
Cheapest flight found366 €
Cheapest month to flyOctober

Finding cheap flights from Santa Ana John Wayne to Buffalo Niagara: Frequently asked questions

The best price we found for a return flight from Santa Ana John Wayne to Buffalo Niagara is 366 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Santa Ana John Wayne to Buffalo Niagara. But we found flights with one or more stops from 366 €.
As of September 2025, there are no flights flying from Santa Ana John Wayne to Buffalo Niagara.
The cheapest month to fly from Santa Ana John Wayne to Buffalo Niagara is usually October.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Santa Ana John Wayne Airport to Buffalo Niagara Airport on Friday, 24 October 2025.
No airlines currently offer direct flights between Santa Ana John Wayne Airport and Buffalo Niagara Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Buffalo Niagara but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Buffalo is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Delta offers the cheapest flight tickets to Buffalo Niagara.

Travelling from John Wayne Airport (SNA) to Buffalo Niagara International Airport (BUF): what you need to know

  • For a stress-free journey, turn up at the airport two hours ahead of international flights and an hour before domestic departures. This way, you can comfortably catch your SNA to BUF flight.

  • During popular months like July, you'll want to get to the airport earlier than normal. Arrive two hours before domestic departures and four hours ahead of an international flight whenever you're travelling during peak periods in general.

  • If you want to break up your flight, just uncheck 'Direct flights only' when searching for your ticket from John Wayne Airport to Buffalo Niagara International Airport. Here are the most popular stopovers between SNA and BUF:

    • Phoenix Sky Harbour International Airport

    • O'Hare International Airport

    • Minneapolis-St. Paul International Airport

How to find the cheapest flights from John Wayne Airport (SNA) to Buffalo Niagara International Airport (BUF)

  • 173 € is currently the lowest price for a one-way John Wayne Airport to Buffalo Niagara International Airport flight. Return flights start at 366 €. These prices can change based on availability.

  • Don't leave things to the last moment. You're more likely to get cheap tickets from SNA to BUF if you book in advance. Airlines often have some fantastic early bird rates.

  • The 'Whole month' tool shows you the cheapest flights from John Wayne Airport to Buffalo Niagara International Airport across the month. It's an easy way to snap up a bargain if your plans aren't set in stone.

  • Snapping up cheap flights from SNA to BUF couldn't be easier with Price Alerts. Simply set up one of these automatic alerts and we'll get in touch as soon as there's a better deal.

  • Pick your preferred departure and arrival times, airlines and number of stops with the filters. Alternatively, sort your results by 'Cheapest' to get the best deals on flights from John Wayne Airport to Buffalo Niagara International Airport.

Handy information about John Wayne Airport (SNA)

  • You'll find SNA at 18601 Airport Way.

  • 81.53% of flights leaving John Wayne Airport arrive at their destination according to schedule. Given its strong on-time performance, you're unlikely to face delays when flying out of SNA.

  • John Wayne Airport is about 8 kilometres from central Santa Ana. If you're driving, catching a cab or ride-sharing from the centre, it'll take 15 minutes or so to arrive, depending on the traffic.

  • The trip when using public transport usually takes 1 hour 5 minutes.

  • Catching an early flight from John Wayne Airport to Buffalo Niagara International Airport? Avoid the hassle of rushing to the terminal (and enjoy a little extra shut-eye) by picking one of these stays close to SNA:

Arriving at Buffalo Niagara International Airport (BUF)

  • The last thing you want is a long journey to your hotel if you're getting in late on a John Wayne Airport to Buffalo Niagara International Airport flight. Stay at one of these accommodation options near BUF instead:

  • Begin your adventure by picking up a Buffalo Niagara International Airport rental car. Grab a set of wheels from Dollar, Hertz or Budget and experience the lesser-explored corners of Buffalo and beyond.

  • To lock in the lowest price, book your vehicle from Buffalo Niagara International Airport around two weeks before your trip.

Getting from Buffalo Niagara International Airport (BUF) to central Buffalo

  • BUF is located at Genesee Street.

  • Buffalo Niagara International Airport is approximately 18 kilometres from the centre of Buffalo. The drive time takes about 20 minutes.

  • Getting there by public transport takes around 1 hour 15 minutes.

When to fly to Buffalo Niagara International Airport (BUF)

  • The quietest month for a flight from John Wayne Airport to Buffalo Niagara International Airport is May, while August is the most popular. Choose the ideal time to go to Buffalo based on whether you prefer a more relaxed vibe or a faster pace.

  • Before locking in your flight from John Wayne Airport to Buffalo Niagara International Airport, think about the type of weather you enjoy. July is the warmest month in Buffalo, with temperatures ranging from 15ºC (59ºF) to 28ºC (82ºF).

  • If you like travelling in cooler conditions, look for a cheap ticket from SNA to BUF in January. Temperatures average between -10ºC (14ºF) and 2ºC (36ºF) then.

Explore more of United States

  • Buffalo has loads to offer, but there are so many other parts of United States waiting to be discovered. Around 467 kilometres south-east of Buffalo, a visit to New York will keep your itinerary packed. Don't miss top attractions like Statue of Liberty, Central Park and Empire State Building.

  • If you want to check out another major destination in United States, consider Philadelphia, roughly 451 kilometres south-east of Buffalo. Liberty Bell, Independence Hall and Philadelphia Museum of Art are key reasons to visit.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.