241 € Cheap Flights from Des Moines to Louisville Muhammad Ali International

Compare Des Moines to Louisville Muhammad Ali International flight deals

Find the cheapest month or even day of the year to fly to Louisville Muhammad Ali International

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Flight deals from Des Moines Airport to Louisville Muhammad Ali International Airport

Looking for a cheap last-minute deal or the best return flight from Des Moines Airport to Louisville Muhammad Ali International Airport? If you want to travel next month, return fares start from 278 €. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Des Moines to Louisville Muhammad Ali International

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Des Moines to Louisville Muhammad Ali International flights are currently cheapest in May.

Des Moines to Louisville Muhammad Ali International: Alternative routes

Compare routes from Des Moines to Louisville below. You may find an airport to fly into that's cheaper, faster, or easier than Louisville Muhammad Ali International.

Des Moines to Louisville: Flight information

The things to know before you go.
Cheapest flight found241 €
Cheapest month to flyMay

Finding cheap flights from Des Moines to Louisville Muhammad Ali International: Frequently asked questions

The best price we found for a return flight from Des Moines to Louisville Muhammad Ali International is 241 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Des Moines to Louisville Muhammad Ali International. But we found flights with one or more stops from 241 €.
As of March 2026, there are no flights flying from Des Moines to Louisville Muhammad Ali International.
The cheapest month to fly from Des Moines to Louisville Muhammad Ali International is usually May.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Des Moines Airport to Louisville Muhammad Ali International Airport on Tuesday, 5 May 2026.
No airlines currently offer direct flights between Des Moines Airport and Louisville Muhammad Ali International Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Louisville Muhammad Ali International but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Louisville is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Southwest Airlines offers the cheapest flight tickets to Louisville Muhammad Ali International.

Flying from Des Moines International Airport (DSM) to Louisville International Airport-Standiford Field (SDF): what you need to know

  • Leave enough time to catch your DSM to SDF flight. It's generally best to arrive two hours before international departures and an hour ahead for domestic flights.

  • During popular months such as July, it's best to get to the airport even earlier. Plan to arrive two hours before domestic departures and four hours ahead of an international flight when you travel during peak periods in general.

  • We make it a cinch to book a flight with a stopover. To see your options for tickets from Des Moines International Airport to Louisville International Airport-Standiford Field, uncheck 'Direct flights only.' Then, choose a flight offering a stop long enough to tour your chosen city. Stopovers between DSM and SDF include:

    • O'Hare International Airport

    • Minneapolis-St. Paul International Airport

    • Detroit Metropolitan Wayne County Airport

How to find the cheapest flights from Des Moines International Airport (DSM) to Louisville International Airport-Standiford Field (SDF)

  • Currently, 116 € is the lowest price we've found for a one-way Des Moines International Airport to Louisville International Airport-Standiford Field flight. The best price for a return plane ticket is 241 €. Remember that fares may change due to availability when booking.

  • To pick up cheap tickets from DSM to SDF, book in advance. Airlines generally offer lower prices when flights are first released.

  • The 'Whole month' search function shows you the cheapest flights from Des Moines International Airport to Louisville International Airport-Standiford Field throughout the month. It's a great way to find a bargain if your dates aren't set in stone.

  • Finding cheap flights from DSM to SDF is easy with Price Alerts. Simply create one of these automatic alerts and we'll get in touch as soon as a new deal comes up.

  • Tailor your trip using filters. Choose your ideal arrival and departure times, airlines and total journey duration. You can also sort the results by 'Cheapest,' 'Best' or 'Fastest' flights from Des Moines International Airport to Louisville International Airport-Standiford Field.

Handy information about Des Moines International Airport (DSM)

  • You'll find DSM at 5800 Fleur Drive, Suite 201.

  • Des Moines International Airport scores top marks for on-time performance. 80.45% of flights that take off from DSM reach their destination without delay.

  • Des Moines International Airport is about 10 kilometres from central Des Moines. If you're ride-sharing, catching a cab or driving from the centre, it'll take 15 minutes or so to arrive, depending on the traffic.

  • You can expect a journey time of about 45 minutes when using public transport.

  • Get your journey off to a hassle-free start by staying near DSM. Whether you have an early flight from Des Moines International Airport to Louisville International Airport-Standiford Field or just don't like being rushed, these stays have you covered:

Arriving at Louisville International Airport-Standiford Field (SDF)

Getting from Louisville International Airport-Standiford Field (SDF) to central Louisville

  • You'll find SDF at 600 Terminal Drive.

  • Louisville International Airport-Standiford Field to central Louisville has a drive time of about 25 minutes. It's approximately 23 kilometres away.

  • If you're using public transport, expect a journey of roughly 2 hours 40 minutes.

When to fly to Louisville International Airport-Standiford Field (SDF)

  • It's time to work out your dates for your flight from Des Moines International Airport to Louisville International Airport-Standiford Field. July is the most popular month to visit Louisville. If you like a more laid-back vibe, go in March.

  • The warmest month in Louisville is July, with the temperature ranging between 17ºC (63ºF) and 33ºC (91ºF). Book your flights from Des Moines International Airport to Louisville International Airport-Standiford Field in this month if you enjoy this type of weather.

  • If you'd rather travel in cooler conditions, search for a cheap ticket from DSM to SDF in January. Average temperatures are between -8ºC (18ºF) and 9ºC (48ºF) then.

Explore more of United States

  • Louisville has loads to offer, but there are so many other parts of United States just waiting to be explored. About 434 kilometres north-west of Louisville, a trip to Chicago will keep you on the move. Start with leading sights like Millennium Park, Art Institute of Chicago and LandShark Beer Garden at Navy Pier.

  • Around 290 kilometres north-east of Louisville, Columbus is another favourite stop in United States. Start your sightseeing at Franklin Park Conservatory and Botanical Gardens, Ohio Statehouse and German Village.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.