205 € Cheap Flights from Medellin to Santo Domingo

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Flight deals from Medellin to Santo Domingo

Looking for a cheap last-minute deal or the best return flight from Medellin to Santo Domingo? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Medellin to Santo Domingo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Medellin to Santo Domingo flights are currently cheapest in September.

Direct flights from Medellin to Santo Domingo

Alternative Medellin to Santo Domingo routes

Looking for the cheapest, fastest or easiest route from Medellin to Santo Domingo? You could fly into the following airports instead.

Medellin to Santo Domingo: Flight information

The things to know before you go.
Cheapest flight found205 €
Cheapest month to flySeptember
Average flight time2 hrs, 33 mins
Most popular airlineArajet
Average flights per week16

Finding cheap flights from Medellin to Santo Domingo: Frequently asked questions

There are 3 airports in Santo Domingo: La Isabela International, Santo Domingo Las Americas and Samana.
The best price we found for a return flight from Medellin to Santo Domingo is 205 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
2 hours and 33 minutes is the average flight time from Medellin to Santo Domingo.
Arajet, World Ticket Ltd and Copa Airlines Colombia fly direct from Medellin to Santo Domingo.
As of August 2025, there are 144 flights per week flying from Medellin to Santo Domingo.
The cheapest month to fly from Medellin to Santo Domingo is usually September.
If you're flying from Medellin, the cheapest airport near Santo Domingo is Santo Domingo Las Americas – which is 23.4 km away from the centre of Santo Domingo. We've found flights into this airport from 205 €.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Medellin to Santo Domingo on Wednesday, 3 September 2025.
Yes – the average flight time is 2 hours and 33 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santo Domingo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santo Domingo is around 40 days in advance, so don’t leave your flight to the last minute.
In August, the average temperature is usually around 28°C. August is typically the warmest month in Santo Domingo, when it usually averages around 31°C. You can expect the least rain in March. The coldest month is January, with temperatures averaging 21°C. The rainiest month is September.
The cheapest airline that flies to Santo Domingo is Arajet .

Travelling from Medellin to Santo Domingo: what you need to know

  • Planning your holiday starts with working out where you'll fly out of in Medellin. Jose Maria Cordova International Airport (MDE) is the city's main base, so check out your options for booking a flight from Medellin to Santo Domingo jetting off from here.

  • Touch down in Santo Domingo at Las Americas International Airport (SDQ) or Dr. Joaquin Balaguer International Airport (JBQ).

  • The average duration of a direct Medellin to Santo Domingo flight is 2 hours 35 minutes.

  • Santo Domingo's timezone is UTC-4, making Santo Domingo one hour ahead of Medellin.

  • With nine flights a week between the two airports, Jose Maria Cordova International Airport (MDE) to Las Americas International Airport (SDQ) is the most popular route. Board the first flight from Medellin to Santo Domingo with Wingo at 07:16. If you'd like to make the most of your day before flying, the latest departure from MDE to SDQ is with Arajet at 20:25.

  • To ensure you don't miss your Medellin to Santo Domingo flight, leave plenty of time to navigate the airport and find your gate. Arriving two hours before international departures and one hour before domestic flights is the general travel rule.

  • During popular months such as August, you'll want to get to the airport even earlier. Plan to arrive two hours before domestic departures and four hours ahead for an international flight whenever you're travelling during high season in general.

How to find the cheapest flights from Medellin to Santo Domingo

  • The cheapest price we've seen for a one-way ticket from Medellin to Santo Domingo is 133 €. For a return flight on this route, the best price is 205 €. Depending on the availability and when you book, these fares can change.

  • Book six months before you want to travel. Pricing trends suggest that this is the ideal window for finding cheap Medellin to Santo Domingo flights.

  • September is the best month for nabbing a fantastic deal on a plane ticket from Medellin to Santo Domingo. If you'd like to travel at a different time of year, the 'Whole month' tool will show you the lowest prices across every month.

  • There's no need to search every day to see if fares have dropped when you set up a Price Alert. We'll tell you the moment there's a better deal on cheap flights from Medellin to Santo Domingo.

  • Choose your preferred departure and arrival times, airlines and number of stops with the filters. Alternatively, sort your Medellin to Santo Domingo flight results by 'Best,' 'Fastest' or 'Cheapest.'

Flying from Medellin

Jose Maria Cordova International Airport (MDE)

  • If you're searching for a direct flight from Medellin to Santo Domingo, you can leave from Jose Maria Cordova International Airport (MDE). Get from MDE to Las Americas International Airport (SDQ) in one continuous trip.

  • Arajet is a popular carrier that offers direct Medellin to Santo Domingo plane tickets leaving from MDE.

  • Consider adding a stopover to potentially find a cheaper Medellin to Santo Domingo flight. Just uncheck 'Direct flights only' when searching for departures from Jose Maria Cordova International Airport. Break up your trip (and maybe save some cash) by stopping at one of these airports:

    • Simon Bolivar International Airport (CCS)

    • El Dorado International Airport (BOG)

    • Rafael Nunez International Airport (CTG)

  • Central Medellin to MDE is around 18 kilometres. Depending on traffic conditions, it'll take you about 35 minutes to get there if you're driving, ride-sharing or catching a cab.

  • Catching an early flight from Medellin to Santo Domingo? Avoid the last-minute rush to the airport (and get some extra shut-eye) by choosing one of these hotels close to Jose Maria Cordova International Airport:

  • When it comes to the on-time performance of Jose Maria Cordova International Airport, data shows 69.76% of flights arrive within the scheduled time frame.

Arriving in Santo Domingo

Las Americas International Airport (SDQ)

Dr. Joaquin Balaguer International Airport (JBQ)

  • The centre of Santo Domingo is around 13 kilometres from Dr. Joaquin Balaguer International Airport (JBQ). After your flight from Medellin to Santo Domingo has touched down and you've made your way to arrivals, the drive should take about 25 minutes.

  • Moderno Apartamento Para tu Estancia is one accommodation option within a short drive of JBQ. Unpack your bags here after your flight from Medellin to Santo Domingo and then hang the 'Do not disturb' sign to enjoy some uninterrupted rest.

  • Pick up a Dr. Joaquin Balaguer International Airport rental car and see and do more with your own set of wheels. FlexWays is just moments from your arrival gate, so you'll be on the road in a flash.

  • Avoid filling out paperwork at the rental desk by completing your booking beforehand. Secure your ride from JBQ in advance so you can just get the keys and go.

Best time to go to Santo Domingo

  • It's time to choose your travel dates for your flight from Medellin to Santo Domingo. January is the most popular month to visit Santo Domingo. If you like a more peaceful vibe, go in May.

  • Book a Medellin to Santo Domingo ticket departing in September if you're eager to visit the city during its warmest month. Expect temperatures in Santo Domingo to range from 23ºC (73ºF) to 33ºC (91ºF).

  • Search for cheap flights from Medellin to Santo Domingo in February if you'd rather travel during cooler conditions. Temperatures are at their lowest then, ranging between 19ºC (66ºF) and 29ºC (84ºF) on average.

More about Santo Domingo

  • Once you've booked your flight from Medellin to Santo Domingo, choose a hotel that puts you where you want to be. Make one of these options your base for exploring Santo Domingo:

  • Alcazar de Colon and National Pantheon (Pantheon Nacional) are just a couple of the leading attractions to put on your Santo Domingo must-do list. Keep the momentum going by heading to National Palace.

Explore more of Dominican Republic

  • You've visited Santo Domingo, now it's time to explore more of Dominican Republic. Journey around 13 kilometres east to Santo Domingo Este to check off its must-visit sights. From Museo Las Tres Aves to billeteros Park and Abuela Mota Final Resting Place, your itinerary will be busy.

  • Around 64 kilometres east of Santo Domingo, San Pedro de Macorís is another essential stop in Dominican Republic. No visit is complete without checking out El Parquecito, Patrimonio arquitectónico de la ciudad de San Pedro de Macoris and Museo Cultural San Pedro.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.