181 € Cheap Flights from Mexico City (MEXA) to Santo Domingo (SDQA)

Your route at a glance

Cheapest deal181 €
Cheapest monthMarch
Average flight duration4 hours and 20 minutes
Most popular airlineAeromexico

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Flight deals from Mexico City to Santo Domingo

Looking for a cheap last-minute deal or the best return flight from Mexico City to Santo Domingo? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Mexico City to Santo Domingo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Mexico City to Santo Domingo flights are currently cheapest in March.

Direct flights from Mexico City to Santo Domingo

Alternative Mexico City to Santo Domingo routes

Looking for the cheapest, fastest or easiest route from Mexico City to Santo Domingo? You could fly into the following airports instead.

Finding cheap flights from Mexico City to Santo Domingo: Frequently asked questions

There are 3 airports in Santo Domingo: La Isabela International, Santo Domingo Las Americas and Samana.
The best price we found for a return flight from Mexico City to Santo Domingo is 181 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
4 hours and 20 minutes is the average flight time from Mexico City to Santo Domingo.
Arajet, Aeromexico and World Ticket Ltd fly direct from Mexico City to Santo Domingo.
As of December 2025, there are 20 flights per week flying from Mexico City to Santo Domingo.
The cheapest month to fly from Mexico City to Santo Domingo is usually March.
If you're flying from Mexico City, the cheapest airport near Santo Domingo is Santo Domingo Las Americas – which is 23.4 km away from the centre of Santo Domingo. We've found flights into this airport from 181 €.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Mexico City to Santo Domingo on Wednesday, 18 March 2026.
Yes – the average flight time is 4 hours and 20 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santo Domingo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Santo Domingo is around 40 days in advance, so don’t leave your flight to the last minute.
In December, the average temperature is usually around 25°C. August is typically the warmest month in Santo Domingo, when it usually averages around 31°C. You can expect the least rain in March. The coldest month is January, with temperatures averaging 21°C. The rainiest month is September.
The cheapest airline that flies to Santo Domingo is Arajet .

Travelling from Mexico City to Santo Domingo: what you need to know

  • Mexico City is home to two main airports where you can set off on your adventure. Check out your options for reserving a flight from Mexico City to Santo Domingo flying out of Benito Juarez International Airport (MEX) or Felipe Ángeles International Airport (NLU).

  • Las Americas International Airport (SDQ) and Dr. Joaquin Balaguer International Airport (JBQ) are Santo Domingo's chief entry points.

  • Around 4 hours 25 minutes is how long you'll be travelling on a direct Mexico City to Santo Domingo flight.

  • Santo Domingo's timezone is UTC-4, which makes Santo Domingo two hours ahead of Mexico City.

  • Benito Juarez International Airport (MEX) to Las Americas International Airport (SDQ) is the most popular route that connects these two cities. There are seven departures a week to pick from. If you have things to do before heading off, the last flight from Mexico City to Santo Domingo is with Aeromexico at 01:01. Go for the first MEX to SDQ departure operated by Aeromexico at 00:10 to make the most of your first day in Santo Domingo.

  • Leave plenty of time to catch your Mexico City to Santo Domingo flight. Generally, it's best to arrive at least two hours before international departures and an hour ahead for domestic flights.

  • Travelling during a peak time like July? Major public holidays and other high seasons can lead to longer queues and delays at check-in and security. Play it safe and get there up to four hours ahead of international flights and two hours before a domestic departure.

How to find the cheapest flights from Mexico City to Santo Domingo

  • At the moment, 95 € is the best price we've found for a one-way ticket from Mexico City to Santo Domingo. The cheapest price for a return flight is 181 €. Keep in mind fares can change due to demand at the time of booking.

  • Book two months before you want to fly. Research into pricing trends suggests this is the ideal window for finding cheap Mexico City to Santo Domingo flights.

  • Organise your trip for May. That's the best month for scoring an incredible deal on plane tickets from Mexico City to Santo Domingo. If you're flexible with your dates, use the 'Whole month' tool to see the cheapest price across every month.

  • There's no need to search every day to see if prices have dropped when you set up a Price Alert. We'll update you the moment there's a better deal on cheap flights from Mexico City to Santo Domingo.

  • Tailor your flights using filters. Pick your preferred departure and arrival times, total journey duration and airlines. You can also sort your results by 'Fastest,' 'Best' or 'Cheapest' Mexico City to Santo Domingo flights.

Flying from Mexico City

Benito Juarez International Airport (MEX)

  • Set out from Benito Juarez International Airport (MEX) on a nonstop flight from Mexico City to Santo Domingo. From MEX, you can fly straight to Las Americas International Airport (SDQ).

  • Aeromexico is a well-known airline that offers direct Mexico City to Santo Domingo plane tickets leaving from MEX.

  • We make it a breeze to book a Mexico City to Santo Domingo flight with a stopover. To see the options departing from Benito Juarez International Airport, deselect 'Direct flights only.' Next, choose a flight that has a stop long enough to tour the city of your choice. Some popular stopovers include:

    • Miami International Airport (MIA)

    • Cancun International Airport (CUN)

    • El Salvador International Airport (SAL)

  • Travelling from central Mexico City to MEX takes about 55 minutes by public transport. If you drive, ride-share or take a cab, you'll cover the 6 kilometres in 25 minutes or so, depending on traffic conditions.

  • After a hassle-free start to your holiday? Stay near Benito Juarez International Airport. Whether you're taking an early flight from Mexico City to Santo Domingo or just don't like being rushed, these hotels are perfect:

  • Benito Juarez International Airport maintains a solid on-time performance, reducing the likelihood of delays. Departures from MEX arrive at their destination as scheduled 80.91% of the time.

Felipe Ángeles International Airport (NLU)

  • You can catch a direct flight from Mexico City to Santo Domingo leaving from Felipe Ángeles International Airport (NLU). Begin your travels at NLU and step off the plane at Las Americas International Airport (SDQ).

  • Arajet offers direct Mexico City to Santo Domingo plane tickets from NLU. Book your favourite window seat and get to your destination in a single journey.

  • Split up your Mexico City to Santo Domingo flight with a stop so you can freshen up or perhaps go somewhere you've never been before. Top stopovers between Felipe Ángeles International Airport and Santo Domingo are:

    • El Dorado International Airport (BOG)

    • Cancun International Airport (CUN)

    • Tocumen International Airport (PTY)

  • NLU is about 32 kilometres from central Mexico City. It takes 55 minutes or so to get to the airport if you're driving from the city centre. Public transport takes roughly 1 hour 45 minutes.

  • It's your holiday, so why not spend an extra night away at a hotel near Felipe Ángeles International Airport? Before your flight from Mexico City to Santo Domingo, consider staying at Verticca Hotel.

  • Felipe Ángeles International Airport has an on-time performance of 68%. This figure shows how frequently flights that take off from this airport arrive on time.

Arriving in Santo Domingo

Las Americas International Airport (SDQ)

Dr. Joaquin Balaguer International Airport (JBQ)

  • As soon as your flight from Mexico City to Santo Domingo has landed, you can get to the city centre in around 25 minutes by car. Central Santo Domingo is approximately 13 kilometres from Dr. Joaquin Balaguer International Airport (JBQ).

  • Unpack your bags not long after your flight from Mexico City to Santo Domingo at Moderno Apartamento Para tu Estancia. This comfortable accommodation option is an easy drive from JBQ.

  • Line up some great tunes and hit the road in a Dr. Joaquin Balaguer International Airport rental car. Grab a set of wheels from FlexWays and get your trip rolling right away.

  • Generally speaking, the sooner you book, the better the prices and vehicle selection. Lock in your ride from JBQ the moment you know your dates.

Best time to go to Santo Domingo

  • It's time to work out your travel dates for your flight from Mexico City to Santo Domingo. January is the busiest month for a trip to Santo Domingo. If you like a more peaceful vibe, go in May.

  • Lock in a Mexico City to Santo Domingo ticket departing in September if you want to explore the city during its warmest month. You can expect temperatures in Santo Domingo to range from 23ºC (73ºF) to 33ºC (91ºF).

  • Look for cheap flights from Mexico City to Santo Domingo in February if you like travelling in cooler conditions. Temperatures are at their lowest then, ranging between 19ºC (66ºF) and 29ºC (84ºF) on average.

More about Santo Domingo

  • After booking your flight from Mexico City to Santo Domingo, choose a hotel that puts you where you want to be. Make one of these options your base for exploring Santo Domingo:

  • Alcazar de Colon and National Palace are just two of the top attractions to put on your Santo Domingo itinerary. Continue your sightseeing adventures at Basilica Cathedral of Santa Maria la Menor.

Explore more of Dominican Republic

  • Santo Domingo is always a good idea, but there are so many other corners of Dominican Republic you'll want to see. Around 13 kilometres east of Santo Domingo, a visit to Santo Domingo Este will keep your itinerary busy. Don't miss top attractions like Museo Las Tres Aves, billeteros Park and Abuela Mota Final Resting Place.

  • Around 64 kilometres east of Santo Domingo, San Pedro de Macorís is another favourite stop in Dominican Republic. No visit is complete without checking out El Parquecito, Patrimonio arquitectónico de la ciudad de San Pedro de Macoris and Museo Cultural San Pedro.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.