Skyscanner home

501 € Cheap Flights from Chicago O'Hare International to Panama City

Return selected
Return selected
origin
Enter the city you're flying from, or choose from the options below
Include nearby airports
    selected
    destination
    . Enter your destination, or choose from the options below
    Include nearby airports
      selected
      Travellers and cabin class, 1 Adult, Economy
      Copa
      United
      EVA Air

      Compare Chicago O'Hare International to Panama City flight deals

      Find the cheapest month or even day of the year to fly to Panama City

      Book the best Panama City fare with no extra fees

      Flight deals from Chicago O'Hare International to Panama City

      Looking for a cheap last-minute deal or the best return flight from Chicago O'Hare International Airport to Panama City? If you want to travel next month, return fares start from 564 €. Find the lowest prices on one-way and return tickets right here.
      Panama City.501 € per passenger.Departing Fri, 13 Nov, returning Tue, 17 Nov.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Fri, 13 Nov, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Tue, 17 Nov, arriving in Chicago O'Hare International.Price includes taxes and charges.From 501 €, select.
      Panama City.501 € per passenger.Departing Sat, 6 Feb, returning Fri, 12 Feb.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Sat, 6 Feb, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Fri, 12 Feb, arriving in Chicago O'Hare International.Price includes taxes and charges.From 501 €, select.
      Panama City.504 € per passenger.Departing Wed, 18 Nov, returning Wed, 2 Dec.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Wed, 18 Nov, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Wed, 2 Dec, arriving in Chicago O'Hare International.Price includes taxes and charges.From 504 €, select.
      Panama City.534 € per passenger.Departing Mon, 1 Mar, returning Sun, 14 Mar.Return flight with Copa and Avianca.Outbound indirect flight with Copa, departs from Chicago O'Hare International on Mon, 1 Mar, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Sun, 14 Mar, arriving in Chicago O'Hare International.Price includes taxes and charges.From 534 €, select.
      Panama City.564 € per passenger.Departing Sun, 4 Oct, returning Wed, 14 Oct.Return flight with Volaris and Copa.Outbound indirect flight with Volaris, departs from Chicago O'Hare International on Sun, 4 Oct, arriving in Panama City Tocumen International.Inbound indirect flight with Copa, departs from Panama City Tocumen International on Wed, 14 Oct, arriving in Chicago O'Hare International.Price includes taxes and charges.From 564 €, select.
      Panama City.587 € per passenger.Departing Thu, 29 Oct, returning Thu, 5 Nov.Return flight with Frontier Airlines and Copa.Outbound indirect flight with Frontier Airlines, departs from Chicago O'Hare International on Thu, 29 Oct, arriving in Panama City Tocumen International.Inbound indirect flight with Copa, departs from Panama City Tocumen International on Thu, 5 Nov, arriving in Chicago O'Hare International.Price includes taxes and charges.From 587 €, select.
      Panama City.602 € per passenger.Departing Thu, 3 Dec, returning Mon, 7 Dec.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Thu, 3 Dec, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Mon, 7 Dec, arriving in Chicago O'Hare International.Price includes taxes and charges.From 602 €, select.
      Panama City.604 € per passenger.Departing Mon, 1 Mar, returning Sun, 14 Mar.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Mon, 1 Mar, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sun, 14 Mar, arriving in Chicago O'Hare International.Price includes taxes and charges.From 604 €, select.
      Panama City.605 € per passenger.Departing Thu, 29 Oct, returning Thu, 5 Nov.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Thu, 29 Oct, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Thu, 5 Nov, arriving in Chicago O'Hare International.Price includes taxes and charges.From 605 €, select.
      Panama City.607 € per passenger.Departing Wed, 6 Jan, returning Sun, 17 Jan.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Wed, 6 Jan, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sun, 17 Jan, arriving in Chicago O'Hare International.Price includes taxes and charges.From 607 €, select.
      Panama City.609 € per passenger.Departing Mon, 26 Oct, returning Thu, 29 Oct.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Mon, 26 Oct, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Thu, 29 Oct, arriving in Chicago O'Hare International.Price includes taxes and charges.From 609 €, select.
      Panama City.623 € per passenger.Departing Fri, 29 Jan, returning Tue, 2 Feb.Return flight with Arajet and Wingo.Outbound indirect flight with Arajet, departs from Chicago O'Hare International on Fri, 29 Jan, arriving in Balboa.Inbound indirect flight with Wingo, departs from Balboa on Tue, 2 Feb, arriving in Chicago O'Hare International.Price includes taxes and charges.From 623 €, select.
      Panama City.637 € per passenger.Departing Tue, 29 Sep, returning Fri, 2 Oct.Return flight with LATAM Airlines and Copa.Outbound indirect flight with LATAM Airlines, departs from Chicago O'Hare International on Tue, 29 Sep, arriving in Balboa.Inbound indirect flight with Copa, departs from Panama City Tocumen International on Fri, 2 Oct, arriving in Chicago O'Hare International.Price includes taxes and charges.From 637 €, select.
      Panama City.640 € per passenger.Departing Tue, 22 Sep, returning Tue, 29 Sep.Return flight with Volaris and Copa.Outbound indirect flight with Volaris, departs from Chicago O'Hare International on Tue, 22 Sep, arriving in Panama City Tocumen International.Inbound indirect flight with Copa, departs from Panama City Tocumen International on Tue, 29 Sep, arriving in Chicago O'Hare International.Price includes taxes and charges.From 640 €, select.
      Panama City.668 € per passenger.Departing Fri, 6 Aug, returning Mon, 16 Aug.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Chicago O'Hare International on Fri, 6 Aug, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 16 Aug, arriving in Chicago O'Hare International.Price includes taxes and charges.From 668 €, select.
      Panama City.699 € per passenger.Departing Mon, 31 May, returning Mon, 7 Jun.Return flight with United.Outbound indirect flight with United, departs from Chicago O'Hare International on Mon, 31 May, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Mon, 7 Jun, arriving in Chicago O'Hare International.Price includes taxes and charges.From 699 €, select.

      Find the cheapest month to fly from Chicago O'Hare International to Panama City

      We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Chicago O'Hare International to Panama City flights are currently cheapest in November.
      Sep
      from 640 €
      Oct
      from 564 €
      Nov
      from 501 €
      Dec
      from 602 €
      Jan
      from 607 €
      Feb
      from 501 €
      Mar
      from 534 €
      Apr
      from 702 €
      May
      from 703 €
      Jun
      from 701 €
      Jul
      Find prices
      Aug
      from 668 €

      Direct flights from Chicago O'Hare International to Panama City

      Copa
      EVA Air
      United

      Alternative Chicago O'Hare International to Panama City routes

      Looking for the cheapest, fastest or easiest route from Chicago O'Hare International to Panama City? You could fly into the following airports instead.

      Panama City Paitilla

      5km from central Panama City
      Closest
      from 1.484 €
      Search flights

      Balboa

      5km from central Panama City
      from 603 €
      Search flights

      Panama City Tocumen International

      18km from central Panama City
      Cheapest
      from 501 €
      Search flights

      Chicago to Panama City: Flight information

      The things to know before you go.
      Cheapest flight found501 €
      Cheapest month to flyNovember
      Average flight time5 hrs, 23 mins
      Most popular airlineCopa
      Average flights per week54

      Finding cheap flights from Chicago O'Hare International to Panama City: Frequently asked questions

      There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
      The best price we found for a return flight from Chicago O'Hare International to Panama City is 501 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
      5 hours and 23 minutes is the average flight time from Chicago O'Hare International to Panama City.
      Copa, United and EVA Air fly direct from Chicago O'Hare International to Panama City.
      As of September 2026, there are 108 flights per week flying from Chicago O'Hare International to Panama City.
      The cheapest month to fly from Chicago O'Hare International to Panama City is usually November.
      If you're flying from Chicago O'Hare International Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from 501 €.
      After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Chicago O'Hare International Airport to Panama City on Friday, 13 November 2026.
      Yes – the average flight time is 5 hours and 23 minutes.
      We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

      We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.

      In September, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is November, with temperatures averaging 25°C. The rainiest month is July.
      Currently, Copa offers the cheapest flight tickets to Panama City.

      Flying from Chicago O'Hare International Airport (ORD) to Panama City: what you need to know

      • Expect to be travelling for 5 hours 45 minutes. On average, that's the time it takes for a direct flight from Chicago O'Hare International Airport to Panama City.

      • Chicago O'Hare International Airport is located in Chicago. Following the UTC-5 timezone, Panama City is one hour ahead of Chicago.

      • Chicago O'Hare International Airport (ORD) to Panama City Tocumen International Airport (PTY) is the most popular route, with 14 weekly departures to choose from. If you have things to do before leaving, the last flight from ORD to PTY is with Copa Airlines at 15:10. Choose the first departure operated by Copa Airlines at 01:07 if you want to fly out earlier.

      • For a smooth journey, turn up at the airport two hours ahead of international flights and one hour before domestic departures. This will give you plenty of time to catch your ORD to Panama City flight.

      • Travelling during a popular month such as July? Public holidays and other high seasons can mean longer queues and delays at check-in and security. Play things extra safe and arrive up to four hours before an international flight and two hours before a domestic departure.

      • You can book a direct Chicago O'Hare International Airport to Panama City ticket. Begin your trip at ORD and arrive at Panama City Tocumen International Airport (PTY).

      • Look out for promotions from Copa Airlines. This carrier has direct flights from Chicago O'Hare International Airport to Panama City.

      • We make it a breeze to book plane tickets from ORD to Panama City with a stopover. To see your options, uncheck 'Direct flights only.' Next, choose a flight offering a stop long enough to tour the city of your choice. Popular stopovers include:

        • Atlanta Hartsfield-Jackson International Airport (ATL)

        • Miami International Airport (MIA)

        • Raleigh-Durham International Airport (RDU)

      • ORD is about 26 kilometres from central Chicago. If you're driving, ride-sharing or catching a taxi from the centre, it'll take you 30 minutes or so to get there, depending on traffic conditions. If you're planning to take public transport, expect the trip time to be around 45 minutes.

      • In search of a hotel close to ORD? If you're catching an early flight from Chicago O'Hare International Airport to Panama City, these accommodation options put the terminal practically at your doorstep:

      • 70% of flights taking off from Chicago O'Hare International Airport touch down at their destination on schedule.

      • ORD's address is 10000 West O'Hare.

      How to find the cheapest flights from Chicago O'Hare International Airport (ORD) to Panama City

      • The lowest price we've found for a one-way Chicago O'Hare International Airport to Panama City flight is 224 €. The cheapest price for a return flight is 501 €. Keep in mind fares may change due to demand at the time of booking.

      • Lock in cheap flights from ORD to Panama City by booking one month ahead. Based on our research, that's the best time for picking up a bargain.

      • June is the best month for picking up an amazing deal on Chicago O'Hare International Airport to Panama City tickets. If you need to travel during a different time of year, the 'Whole month' tool will give you the lowest prices across every month.

      • Locking in a cheap flight from ORD to Panama City is a breeze with Price Alerts. All you need to do is set up one of these automatic notifications and we'll notify you as soon as a deal gets even better.

      • Tailor your flights with filters. Select your departure and arrival times, total journey duration and airlines. You can also sort results by 'Cheapest,' 'Best' or 'Fastest' flights from Chicago O'Hare International Airport to Panama City.

      Airports in Panama City

      Panama City Tocumen International Airport (PTY)

      • Panama City Tocumen International Airport (PTY) is around 24 kilometres from the centre of Panama City. If you're grabbing a taxi or a ride-share, the drive will take roughly 35 minutes.

      • It typically takes 50 minutes to get there by public transport.

      • Consider booking a hotel close to PTY if you're coming in on a late flight from Chicago O'Hare International Airport to Panama City. Settle into one of these accommodation options and skip the long transfer:

      • To get the best deal, reserve your ride from Panama City Tocumen International Airport around three weeks ahead of your flight from ORD to Panama City.

      Panama Pacifico International Airport (BLB)

      • After your flight from Chicago O'Hare International Airport to Panama City has touched down, you can reach the city centre in about 10 minutes by car. Central Panama City is roughly 6 kilometres from Panama Pacifico International Airport (BLB).

      • You can expect the trip to take about 20 minutes on public transport.

      • There are some great places to park your luggage (and yourself) near BLB. Tuck yourself in and get cosy after your ORD to Panama City flight at one of these perfectly located options:

      • Score the best price by reserving your ride from BLB one week in advance. You can also expect to have a wider range of vehicles.

      Best time to go to Panama City

      • September is the quietest month for flights from Chicago O'Hare International Airport to Panama City, while January is the most popular. Pick the best time to visit Panama City based on whether you prefer a bustling atmosphere or a more laid-back vibe.

      • Book a Chicago O'Hare International Airport to Panama City plane ticket with a departure in March if you want to experience the city during its warmest month. Expect temperatures to range from 21ºC (70ºF) to 32ºC (90ºF).

      • Search for cheap tickets from ORD to Panama City in January if you'd rather travel when it's cooler. Temperatures are at their lowest then, ranging between 22ºC (72ºF) and 31ºC (88ºF) on average.

      More about Panama City

      • Start your Panama City trip off on the right foot by choosing the perfect place to stay. After booking your flight from Chicago O'Hare International Airport to Panama City, browse our selection of accommodation options including:

      • There are so many things to explore in this city it can be hard to figure out where to start. Metropolitan Cathedral (Catedral Metropolitan), Casco Viejo and Independence Square are highlights which should feature on any well-planned Panama City itinerary.

      Explore more of Panama

      • You've done Panama City, now it's time to explore other parts of Panama. Travel about 322 kilometres west to David to check off its top sights. From Museo Antropológico y Etnográfico Dr. Roberto De La Guardia to Raptors To The Rescue and Unachi Botanical garden, there's plenty to keep you on the go.

      • Another favourite stop in Panama, Santiago de Veraguas is located about 193 kilometres southwest of Panama City. Make room in your schedule for highlights including Santiago the Apostle Cathedral, Santiago de Veraguas.

      Plan the rest of your trip from Chicago to Panama City

      Prices shown on this page are estimated lowest prices only. Found in the last 12 days.