135 € Cheap Flights from Panama City (PTYA) to Cali (CLO)

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Flight deals from Panama City to Cali

Looking for a cheap last-minute deal or the best return flight from Panama City to Cali? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Panama City to Cali

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Cali flights are currently cheapest in February.

Direct flights from Panama City to Cali

Panama City to Cali: Alternative routes

Compare routes from Panama City to Cali below. You may find an airport to fly into that's cheaper, faster, or easier than Cali.

Panama City to Cali: Flight information

The things to know before you go.
Cheapest flight found135 €
Cheapest month to flyFebruary
Average flight time1 hr, 37 mins
Most popular airlineCopa
Average flights per week158

Finding cheap flights from Panama City to Cali: Frequently asked questions

The best price we found for a return flight from Panama City to Cali is 135 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
1 hour and 36 minutes is the average flight time from Panama City to Cali.
Copa, United and KLM fly direct from Panama City to Cali.
As of December 2025, there are 79 flights per week flying from Panama City to Cali.
The cheapest month to fly from Panama City to Cali is usually February.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Cali Airport on Monday, 16 February 2026.
Yes – the average flight time is 1 hour and 36 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Cali but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Cali is around 40 days in advance, so don’t leave your flight to the last minute.
The cheapest airline that flies to Cali is Wingo .

Flying from Panama City to Alfonso B. Aragon Airport (CLO): What you need to know

  • There are two main airports to jet off from in Panama City. Check out your options departing from Tocumen International Airport (PTY) or Panama Pacifico Airport (BLB) when organising your flight from Panama City to Alfonso B. Aragon Airport (CLO).

  • 1 hour 40 minutes is the average journey time for a direct Panama City to Alfonso B. Aragon Airport flight.

  • Panama City and Cali (where Alfonso B. Aragon Airport is located) share the UTC-5 timezone. That means you won't have to adjust your watch when you arrive.

  • Tocumen International Airport (PTY) to Alfonso B. Aragon Airport (CLO) is the most popular route. There are 29 direct departures a week to pick from. If you prefer to head out later, hop on the last flight with Copa Airlines at 9:46pm. Go for the first PTY to CLO departure operated by Copa Airlines at 9:12am if you'd rather get a move on.

  • Your flight from Panama City to CLO won't wait if you're late, so don't forget to check in on time. Arrive up to one hour in advance for domestic flights and two hours ahead for international travel.

  • Longer lines at security and check-in are more likely if you're flying during high season, so give yourself some extra breathing space. The recommendation for peak times? Get there up to four hours early for international flights and two hours for domestic departures.

Airports in Panama City

Tocumen International Airport (PTY)

  • Tocumen International Airport (PTY) is a convenient option for travelling directly to your destination. Nonstop flights from Panama City to Alfonso B. Aragon Airport (CLO) depart from this terminal.

  • Copa Airlines is a popular carrier that operates direct flights from Panama City to Alfonso B. Aragon Airport departing from PTY.

  • Copa Airlines is the airline most travellers choose for flights from PTY to CLO.

  • With a dependable 90.09% of services arriving on schedule, Copa Airlines is the most punctual carrier on this route.

  • Located around 21 kilometres from the centre of Panama City, PTY can be reached in about 20 minutes by car, depending on traffic. The journey by public transport will take roughly 1 hour 5 minutes.

  • Want an easy start to your break? Stay near Tocumen International Airport. Whether you're catching an early flight from Panama City to Alfonso B. Aragon Airport or want to avoid feeling rushed, these hotels are the answer:

  • Tocumen International Airport earns top marks for on-time performance. 86.03% of flights that depart PTY arrive at their destination as scheduled.

Marcos A. Gelabert International Airport (PAC)

  • PAC is around 2 kilometres from central Panama City. It'll take 5 minutes or so to get to the airport in a car from the city centre. Public transport takes roughly 25 minutes.

  • Kick off your holiday early with an additional night away from home. Before catching your Panama City to CLO flight, stay in one of these hotels close to Marcos A. Gelabert International Airport:

Panama Pacifico Airport (BLB)

  • Get to your destination faster from Panama Pacifico Airport (BLB). Direct flights from Panama City to Alfonso B. Aragon Airport are available from here.

  • Wingo is one reputable carrier that offers direct Panama City to CLO plane tickets from BLB.

  • Wingo is the most frequently booked airline offering flights from BLB to CLO.

  • With an impressive 100.0% of services landing on schedule, Wingo is the most punctual carrier on this route.

  • Is around BLB 16 kilometres from central Panama City. The drive from the city centre to the airport takes about 20 minutes.

  • Make catching an early Panama City to Alfonso B. Aragon Airport flight the easiest part of your trip. Book a room at one of these accommodation options close to Panama Pacifico Airport and get to the check-in counter without rushing:

  • BLB has an on-time performance rating of 86.75%. This means the majority of its flights touch down on schedule and your trip is smooth and easy.

About Alfonso B. Aragon Airport (CLO)

  • It's hard to beat the convenience of staying close to the terminal if you've landed on a late flight from Panama City to Alfonso B. Aragon Airport. Hotel Royal Elim Internacional and Hotel Sin Escala are great choices near CLO.

  • Fast-track your adventure by picking up an Alfonso B. Aragon Airport rental car. Grab your wheels from Localiza, Alamo or Budget and experience the lesser-explored corners of Cali and beyond.

  • Lock in the best rate by reserving your vehicle around two weeks before your Panama City to Alfonso B. Aragon Airport flight.

How to find the cheapest flights from Panama City to Alfonso B. Aragon Airport (CLO)

  • 68 € is currently the lowest price for a one-way ticket from Panama City to Alfonso B. Aragon Airport. Return flights start at 135 €. These prices may change based on demand and availability.

  • Book 11 months before travelling. Pricing trends show that this is the ideal window for finding cheap flights from Panama City to CLO.

  • Plan your trip for April. That's the best month for scoring cheap Panama City to Alfonso B. Aragon Airport tickets. If you're flexible with your travel dates, use the 'Whole month' tool to find the cheapest price across each month.

  • There's no need to check back in every day to find out if prices have dropped when you create a Price Alert. We'll notify you as soon as a lower fare pops up on plane tickets from Panama City to CLO.

  • Bag the best deal on a flight from Panama City to Alfonso B. Aragon Airport with the help of the filters. Pick your ideal arrival and departure times, number of stops and airlines. You can also sort your results by 'Best,' 'Cheapest' or 'Fastest.'

The best time to fly from Panama City to Alfonso B. Aragon Airport (CLO)

  • April is the quietest month for flights from Panama City to Alfonso B. Aragon Airport (CLO), while August is the busiest. Figure out the ideal time to go to Cali based on whether you want a laid-back vibe or a more bustling atmosphere.

  • The warmest month in Cali is August, with temperatures ranging between 15ºC (59ºF) and 27ºC (81ºF). Book your Panama City to CLO plane ticket then if this is the type of weather you enjoy.

  • January has temperatures of between 14ºC (57ºF) and 27ºC (81ºF). Look for cheap tickets from Panama City to Alfonso B. Aragon Airport around that time if you'd rather travel in cooler conditions.

More about Cali

  • Start your Cali trip off on the right foot by choosing the ideal place to stay. After booking your flight from Panama City to Alfonso B. Aragon Airport, explore our selection of hotels including:

  • There are so many things to discover in this city, it can be hard to work out where to start. Swing Latino, Cristo Rey and El Retiro Park are top attractions which should be on any well-planned Cali itinerary.

Explore more of Colombia

  • Pereira is just one of the many cities in Colombia waiting to be explored once you've seen the sights of Cali. Around 161 kilometres away to the north-east, well-known attractions include Paisaje Cultural Cafetero, Reserva Natural, Termales de San Vicente and Lugar De Contemplación Monte Tabor.

  • Around 161 kilometres north-east of Cali, Ibague is another favourite stop in Colombia. Experience this destination's highlights firsthand at Ibague capital musical de colombia, BioSaludable Tolima Grande Park and Alexander von Humboldt Botanical Garden.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.