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211 € Cheap Flights from Syracuse to Knoxville

Compare Syracuse to Knoxville flight deals

Find the cheapest month or even day of the year to fly to Knoxville

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Flight deals from Syracuse to Knoxville

Looking for a cheap last-minute deal or the best return flight from Syracuse to Knoxville? Find the lowest prices on one-way and return tickets right here.
Knoxville.211 € per passenger.Departing Tue, 4 Nov, returning Tue, 11 Nov.Return flight with Delta.Outbound indirect flight with Delta, departs from Syracuse on Tue, 4 Nov, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Tue, 11 Nov, arriving in Syracuse.Price includes taxes and charges.From 211 €, select.
Knoxville.218 € per passenger.Departing Thu, 2 Oct, returning Mon, 6 Oct.Return flight with Delta.Outbound indirect flight with Delta, departs from Syracuse on Thu, 2 Oct, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Mon, 6 Oct, arriving in Syracuse.Price includes taxes and charges.From 218 €, select.
Knoxville.249 € per passenger.Departing Thu, 12 Feb, returning Sun, 15 Feb.Return flight with Delta.Outbound indirect flight with Delta, departs from Syracuse on Thu, 12 Feb, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Sun, 15 Feb, arriving in Syracuse.Price includes taxes and charges.From 249 €, select.
Knoxville.253 € per passenger.Departing Thu, 21 May, returning Sun, 24 May.Return flight with Delta.Outbound indirect flight with Delta, departs from Syracuse on Thu, 21 May, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Sun, 24 May, arriving in Syracuse.Price includes taxes and charges.From 253 €, select.
Knoxville.273 € per passenger.Departing Tue, 23 Sep, returning Tue, 30 Sep.Return flight with Delta.Outbound indirect flight with Delta, departs from Syracuse on Tue, 23 Sep, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Tue, 30 Sep, arriving in Syracuse.Price includes taxes and charges.From 273 €, select.
Knoxville.358 € per passenger.Departing Fri, 19 Dec, returning Sun, 4 Jan.Return flight with Allegiant Air.Outbound indirect flight with Allegiant Air, departs from Syracuse on Fri, 19 Dec, arriving in Knoxville.Inbound indirect flight with Allegiant Air, departs from Knoxville on Sun, 4 Jan, arriving in Syracuse.Price includes taxes and charges.From 358 €, select.
Knoxville.461 € per passenger.Departing Fri, 26 Sep, returning Fri, 3 Oct.Return flight with Frontier Airlines and Allegiant Air.Outbound indirect flight with Frontier Airlines, departs from Syracuse on Fri, 26 Sep, arriving in Knoxville.Inbound indirect flight with Allegiant Air, departs from Knoxville on Fri, 3 Oct, arriving in Syracuse.Price includes taxes and charges.From 461 €, select.

Find the cheapest month to fly from Syracuse to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Syracuse to Knoxville flights are currently cheapest in November.
Sep
from 273 €
Oct
from 218 €
Nov
from 211 €
Dec
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Jan
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Feb
from 249 €
Mar
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Apr
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May
from 253 €
Jun
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Jul
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Aug
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Syracuse to Knoxville: Alternative routes

Compare routes from Syracuse to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Syracuse to Knoxville: Flight information

The things to know before you go.
Cheapest flight found211 €
Cheapest month to flyNovember

Finding cheap flights from Syracuse to Knoxville: Frequently asked questions

The best price we found for a return flight from Syracuse to Knoxville is 211 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Syracuse to Knoxville. But we found flights with one or more stops from 211 €.
As of September 2025, there are no flights flying from Syracuse to Knoxville.
The cheapest month to fly from Syracuse to Knoxville is usually November.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Syracuse Airport to Knoxville Airport on Tuesday, 4 November 2025.
No airlines currently offer direct flights between Syracuse Airport and Knoxville Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Delta offers the cheapest flight tickets to Knoxville.

Flying from Hancock International Airport (SYR) to McGhee Tyson Airport (TYS): what you need to know

  • Arrive at the airport on time so you don't miss your SYR to TYS flight. Be there at least two hours ahead for international flights and an hour early for domestic departures to avoid sprinting to your gate.

  • Be prepared for bigger queues in popular months like July. Arriving up to four hours ahead of international flights and two hours for domestic departures is a wise move.

  • We make it a breeze to book a flight with a stopover. To see your options for tickets from Hancock International Airport to McGhee Tyson Airport, deselect 'Direct flights only.' Then, choose a flight that has a stop long enough to visit your chosen city. Popular stopovers between SYR and TYS include:

    • Ronald Reagan National Airport

    • Washington Dulles International Airport

    • Detroit Metropolitan Wayne County Airport

How to find the cheapest flights from Hancock International Airport (SYR) to McGhee Tyson Airport (TYS)

  • 239 € is the best price for a one-way Hancock International Airport to McGhee Tyson Airport flight. Return flights start at 211 €. These fares may change depending on demand.

  • Don't leave everything to the last moment. You're more likely to get cheap tickets from SYR to TYS if you book early. Airlines often have some great early bird rates.

  • The 'Whole month' search function shows you the cheapest flights from Hancock International Airport to McGhee Tyson Airport across every month. It's a great way to snap up a bargain if your travel dates aren't set in stone.

  • Getting your hands on cheap flights from SYR to TYS is a piece of cake with Price Alerts. Simply set up one of these automatic alerts and we'll notify you when fares go down.

  • Tailor your flights with filters. Pick your ideal arrival and departure times, airlines and total journey duration. You can also sort the results by 'Fastest,' 'Cheapest' or 'Best' flights from Hancock International Airport to McGhee Tyson Airport.

Handy information about Hancock International Airport (SYR)

  • You'll find SYR at City Hall.

  • 72.76% of flights that take off from Hancock International Airport reach their destination on schedule.

  • To get to Hancock International Airport from central Syracuse, it takes about 25 minutes if you're planning to drive. Of course, this depends on traffic. It's approximately 18 kilometres from the airport to the city centre.

  • Planning to catch public transport? Expect a journey time of around 1 hour 10 minutes.

  • Get your break off to a hassle-free start by staying near SYR. Whether you're taking an early flight from Hancock International Airport to McGhee Tyson Airport or just don't want to be rushed, these hotels are perfect:

Arriving at McGhee Tyson Airport (TYS)

  • If you're landing on a late Hancock International Airport to McGhee Tyson Airport flight, nothing beats the convenience of staying near the terminal. Collect your bags from the carousel and then be showered and sleeping not long after at one of these accommodation options near TYS:

  • Go wherever you want, whenever you want with a McGhee Tyson Airport rental car. Book your wheels from Budget, Alamo or Avis and discover more of Knoxville and beyond.

  • To get the lowest price, book your ride from McGhee Tyson Airport about three weeks before you travel.

Getting from McGhee Tyson Airport (TYS) to central Knoxville

  • The address for TYS is 2055 Alcoa Highway.

  • From McGhee Tyson Airport, Knoxville is approximately 23 kilometres away. It takes around 20 minutes to drive to the centre.

When to fly to McGhee Tyson Airport (TYS)

  • The quietest month for a flight from Hancock International Airport to McGhee Tyson Airport is February, while July is the busiest. Pick the best time to go to Knoxville based on whether you prefer a laid-back vibe or a more bustling atmosphere.

  • When booking your flight from Hancock International Airport to McGhee Tyson Airport, consider the type of weather you enjoy. July is the warmest month in Knoxville, with the temperature ranging from 17ºC (63ºF) to 32ºC (90ºF).

  • If you like travelling in cooler conditions, look for a cheap ticket from SYR to TYS in January. Temperatures average between -6ºC (21ºF) and 11ºC (52ºF) then.

Explore more of United States

  • You've seen Knoxville, now it's time to discover other parts of United States. Journey about 451 kilometres north to Columbus to tick off its leading sights. From Franklin Park Conservatory and Botanical Gardens to Ohio Statehouse and German Village, you've got a jam-packed schedule ahead.

  • Around 467 kilometres north-west of Knoxville, Indianapolis is another essential stop in United States. Experience major highlights starting with The Children's Museum of Indianapolis, Indianapolis Museum of Art and Indianapolis Zoo.

Plan the rest of your trip from Syracuse to Knoxville

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.