Flights from Chicago O'Hare International Airport to South Carolina

Flight deals from Chicago O'Hare International Airport to South Carolina

Looking for a cheap last-minute deal or the best return flight from Chicago O'Hare International Airport to South Carolina? If you want to travel next month, return fares start from 187 €. Find the lowest prices on one-way and return tickets right here.

Myrtle Beach.187 € per passenger.Departing Wed, 10 Jun, returning Wed, 17 Jun.Return flight with United.Outbound direct flight with United departs from Chicago O'Hare International on Wed, 10 Jun, arriving in Myrtle Beach International .Inbound direct flight with United departs from Myrtle Beach International on Wed, 17 Jun, arriving in Chicago O'Hare International.Price includes taxes and charges.From 187 €, select.

Charleston.221 € per passenger.Departing Tue, 30 Jun, returning Tue, 7 Jul.Return flight with United.Outbound direct flight with United departs from Chicago O'Hare International on Tue, 30 Jun, arriving in Charleston.Inbound direct flight with United departs from Charleston on Tue, 7 Jul, arriving in Chicago O'Hare International.Price includes taxes and charges.From 221 €, select.

Greenville.228 € per passenger.Departing Wed, 19 Aug, returning Mon, 24 Aug.Return flight with Frontier Airlines and Allegiant Air.Outbound indirect flight with Frontier Airlines, departs from Chicago O'Hare International on Wed, 19 Aug, arriving in Greenville-Spartanburg.Inbound indirect flight with Allegiant Air, departs from Greenville-Spartanburg on Mon, 24 Aug, arriving in Chicago O'Hare International.Price includes taxes and charges.From 228 €, select.

Columbia.230 € per passenger.Departing Thu, 27 Aug, returning Sun, 30 Aug.Return flight with United.Outbound direct flight with United departs from Chicago O'Hare International on Thu, 27 Aug, arriving in Columbia Metropolitan.Inbound direct flight with United departs from Columbia Metropolitan on Sun, 30 Aug, arriving in Chicago O'Hare International.Price includes taxes and charges.From 230 €, select.

Hilton Head Island.231 € per passenger.Departing Wed, 2 Sep, returning Wed, 9 Sep.Return flight with United.Outbound direct flight with United departs from Chicago O'Hare International on Wed, 2 Sep, arriving in Hilton Head.Inbound direct flight with United departs from Hilton Head on Wed, 9 Sep, arriving in Chicago O'Hare International.Price includes taxes and charges.From 231 €, select.

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Flying from Chicago O'Hare International Airport to South Carolina

Arm yourself with these facts on the fly.

Cheapest flight found	187 €
Cheapest month to fly	June
Average flight time	2 hrs, 18 mins
Average flights per week	848
Most popular airline	United

How to find cheap flights from Chicago O'Hare International Airport to South Carolina

We've compared the best online travel agents and flight providers on the internet to find the cheapest plane tickets from Chicago O'Hare International Airport to South Carolina. Other savvy travellers recently found return flights from 187 € and one-way tickets from 71 €. Ready to join them? Here are a few tips to help you do it the smart way.

Fly in June

The cheapest time to fly from Chicago O'Hare International Airport to South Carolina is currently June.

Flex your dates for the best rates

If you’re flexible on your departure dates, you can use Skyscanner's whole month tool to find the cheapest day of the year to fly from Chicago O'Hare International Airport to anywhere you choose in South Carolina.

Watch as fares rise and fall

With Price Alerts, we'll let you know when flight prices from Chicago O'Hare International Airport to your chosen airport in South Carolina go up or down so you can book when the time is just right.

Relax – these are fee-free flight tickets

With us, there are no added fees – the South Carolina Airport to South Carolina flight price you see when you search with us is what you pay to the provider.

Frequently asked questions

Are there any direct flights from Chicago O'Hare International Airport to South Carolina?

Yes - direct flights currently operate from Chicago O'Hare International Airport to Myrtle Beach International Airport, Charleston Airport and Columbia Metropolitan Airport in South Carolina.

Which other Chicago airports offer direct flights to South Carolina?

Chicago Midway Airport offers direct flights to South Carolina.

What is the average price of a flight from Chicago O'Hare International Airport to South Carolina?

We looked at all of the upcoming return flights from Chicago O'Hare International Airport to South Carolina we could find over the next 12 months. It looks like 187 € is the best price. This is good, compared to the average South Carolina ticket price of 219 €.

What is the cheapest month to fly from Chicago O'Hare International Airport to South Carolina?

The cheapest month to fly from Chicago O'Hare International Airport to Charleston Airport is currently June.
The cheapest month to fly from Chicago O'Hare International Airport to Columbia Metropolitan Airport is currently August.
The cheapest month to fly from Chicago O'Hare International Airport to Greenville-Spartanburg Airport is currently August.
And the cheapest month to fly from Chicago O'Hare International Airport to Myrtle Beach International Airport is usually June.

Which upcoming date is cheapest to fly from Chicago O'Hare International Airport to South Carolina on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Chicago O'Hare International Airport to South Carolina on Wednesday, 10 June 2026.

If I'm flying from Chicago O'Hare International Airport, where in South Carolina is cheapest to fly into?

If you're flying from Chicago O'Hare International, the cheapest city in South Carolina to fly into is Myrtle Beach. The cheapest airport serving Myrtle Beach at the moment is Myrtle Beach International .