Cheap Flights from Chicago to Greenville-Spartanburg

Compare Chicago to Greenville-Spartanburg flight deals

Find the cheapest month or even day of the year to fly to Greenville-Spartanburg

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Flight deals from Chicago to Greenville-Spartanburg

Looking for a cheap last-minute deal or the best return flight from Chicago to Greenville-Spartanburg? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Chicago to Greenville-Spartanburg

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Chicago to Greenville-Spartanburg flights are currently cheapest in August.

Direct flights from Chicago to Greenville-Spartanburg

Chicago to Greenville-Spartanburg: Alternative routes

Compare routes from Chicago to Greenville below. You may find an airport to fly into that's cheaper, faster, or easier than Greenville-Spartanburg.

Chicago to Greenville: Flight information

The things to know before you go.
Cheapest flight found169 €
Cheapest month to flyAugust
Average flight time1 hr, 59 mins
Most popular airlineUnited
Average flights per week242

Finding cheap flights from Chicago to Greenville-Spartanburg: Frequently asked questions

The best price we found for a return flight from Chicago to Greenville-Spartanburg is 169 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
1 hour and 59 minutes is the average flight time from Chicago to Greenville-Spartanburg.
United, Alaska Airlines and American Airlines fly direct from Chicago to Greenville-Spartanburg.
As of June 2025, there are 242 flights per week flying from Chicago to Greenville-Spartanburg.
The cheapest month to fly from Chicago to Greenville-Spartanburg is usually June 2025.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Chicago to Greenville-Spartanburg Airport on Saturday, 9 August 2025.
Yes – the average flight time is 1 hour and 59 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Greenville-Spartanburg but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Greenville is around 40 days in advance, so don’t leave your flight to the last minute.
The cheapest airline that flies to Greenville-Spartanburg is United .

Travelling from Chicago to Greenville-Spartanburg International Airport (GSP): What you need to know

  • Kick off your journey at one of Chicago's main airports, O'Hare International Airport (ORD) or Chicago Midway International Airport (MDW). Explore your options for booking a flight from Chicago to Greenville-Spartanburg International Airport (GSP) jetting off from either of these.

  • 2 hours is the average journey time for a direct Chicago to Greenville-Spartanburg International Airport flight.

  • The timezone in Greenville is UTC-4, which is one hour ahead of Chicago. Greenville-Spartanburg International Airport is located in Greenville.

  • With 33 direct flights a week between the two airports, O'Hare International Airport (ORD) to Greenville-Spartanburg International Airport (GSP) is the most popular route. United Airlines operates the earliest flight at 7:10am. If you're eager to make the most of your day before taking off, the last flight from ORD to GSP is with American Airlines at 8:20pm.

  • Arriving two hours before an international flight and one hour ahead of a domestic departure are travel rules worth sticking to. Get to the airport on time to board your flight from Chicago to GSP.

  • Heading away during a peak time like a bank holiday? Expect longer queues at security and check-in. To be on the safe side, arrive up to four hours before international flights and two hours ahead of domestic departures.

Airports in Chicago

O'Hare International Airport (ORD)

  • Take the express route from O'Hare International Airport (ORD). Nonstop flights from Chicago to Greenville-Spartanburg International Airport (GSP) operate from here.

  • You can get away on a direct flight from Chicago to Greenville-Spartanburg International Airport with United Airlines. This top carrier operates departures from ORD.

  • United Airlines is the most frequently booked airline offering flights from ORD to GSP.

  • With a reliable 86.0% of services arriving on schedule, American Airlines ranks as the most on-time carrier flying this route.

  • Located around 40 kilometres from central Chicago, ORD can be reached in about 35 minutes by car (depending on traffic). The journey on public transport takes roughly 55 minutes.

  • Want a hassle-free start to your journey? Stay near O'Hare International Airport. Whether you have an early flight from Chicago to Greenville-Spartanburg International Airport or prefer not to rush, these hotels are the answer:

  • When it comes to the on-time performance of O'Hare International Airport, data shows 74.85% of flights arrive within the scheduled time frame.

  • The address for ORD is 10000 West O'Hare.

Chicago Midway International Airport (MDW)

  • MDW is around 19 kilometres from central Chicago. It'll take you 20 minutes or so to get to the airport if you're driving from the city centre. Public transport takes approximately 45 minutes.

  • Flying off with the first light? Think about checking in to one of these accommodation options near Chicago Midway International Airport the day before your Chicago to GSP flight:

  • When it comes to flights staying on schedule, Chicago Midway International Airport has an on-time arrival rate of 77.88%.

  • You'll find MDW at 5700 South Cicero.

Chicago Rockford International Airport (RFD)

  • From the centre of Chicago, RFD is around 137 kilometres away. It takes roughly 1 hour 25 minutes to get to the airport by car and 4 hours 15 minutes or so if you take public transport.

  • Sleep a little longer, move a little slower, and still make your Chicago to Greenville-Spartanburg International Airport flight without having to rush. These accommodation options near Chicago Rockford International Airport make it a breeze to get to the terminal if you're flying out early:

  • The on-time performance record of RFD is 76.19%. In other words, that's how frequently flights from this airport reach their final stop as planned.

  • Chicago Rockford International Airport is located at 2 Airport Cir.

About Greenville-Spartanburg International Airport (GSP)

How to find the cheapest flights from Chicago to Greenville-Spartanburg International Airport (GSP)

  • 93 € is the lowest price for a one-way ticket from Chicago to Greenville-Spartanburg International Airport. A return flight starts at 169 €. These prices may change based on availability.

  • Get your hands on cheap flights from Chicago to GSP by booking one month ahead. According to our research, that's the sweet spot for finding a bargain.

  • June is when you're most likely to find a good deal on a Chicago to Greenville-Spartanburg International Airport ticket. If you want to travel during a different time of year, the 'Whole month' tool will show you the lowest prices across every month.

  • Save time searching for cheap plane tickets from Chicago to GSP by creating a Price Alert. We'll send you an email or notification on the app when a lower fare becomes available.

  • Hunt down a great price on a flight from Chicago to Greenville-Spartanburg International Airport with the help of the filters. Pick your ideal departure and arrival times, airlines and number of stops. You can also sort your results by 'Cheapest,' 'Fastest' or 'Best.'

The best time to fly from Chicago to Greenville-Spartanburg International Airport (GSP)

  • It's time to decide when to book your flight from Chicago to Greenville-Spartanburg International Airport (GSP). August is when most people visit Greenville. If you prefer a quieter vibe, think about going in February.

  • The warmest month in Greenville is July, with temperatures ranging between 19ºC (66ºF) and 34ºC (93ºF). Lock in your Chicago to GSP plane ticket then if that's your idea of comfortable weather.

  • January has temperatures of between -3ºC (27ºF) and 13ºC (55ºF). Look for cheap tickets from Chicago to Greenville-Spartanburg International Airport around that time if you want to travel when it's cooler.

More about Greenville

Explore more of the United States

  • Greenville has its own special appeal, but there are so many other corners of the United States waiting to be explored. About 129 kilometres east of Greenville, a trip to Charlotte will fill your itinerary to the brim. Start with leading attractions like Bechtler Museum of Modern Art, Discovery Place and NASCAR Hall of Fame.

  • Around 241 kilometres south-west of Greenville, Atlanta is another essential stop in the United States. Start your sightseeing at Georgia Aquarium, Birth Home of Martin Luther King, Jr and Fox Theatre.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.