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46 € Cheap Flights from Antofagasta to La Serena

Compare Antofagasta to La Serena flight deals

Find the cheapest month or even day of the year to fly to La Serena

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Flight deals from Antofagasta to La Serena

Looking for a cheap last-minute deal or the best return flight from Antofagasta Airport to La Serena Airport? If you want to travel next month, return fares start from 52 €. Find the lowest prices on one-way and return tickets right here.
La Serena.46 € per passenger.Departing Mon, 20 Jul, returning Wed, 19 Aug.Return flight with JetSmart.Outbound direct flight with JetSmart departs from Antofagasta on Mon, 20 Jul, arriving in La Serena.Inbound direct flight with JetSmart departs from La Serena on Wed, 19 Aug, arriving in Antofagasta.Price includes taxes and charges.From 46 €, select.
La Serena.51 € per passenger.Departing Fri, 14 Aug, returning Wed, 9 Sep.Return flight with JetSmart.Outbound direct flight with JetSmart departs from Antofagasta on Fri, 14 Aug, arriving in La Serena.Inbound direct flight with JetSmart departs from La Serena on Wed, 9 Sep, arriving in Antofagasta.Price includes taxes and charges.From 51 €, select.
La Serena.52 € per passenger.Departing Mon, 13 Jul, returning Thu, 16 Jul.Return flight with JetSmart.Outbound direct flight with JetSmart departs from Antofagasta on Mon, 13 Jul, arriving in La Serena.Inbound direct flight with JetSmart departs from La Serena on Thu, 16 Jul, arriving in Antofagasta.Price includes taxes and charges.From 52 €, select.
La Serena.52 € per passenger.Departing Tue, 15 Sep, returning Tue, 22 Sep.Return flight with JetSmart.Outbound direct flight with JetSmart departs from Antofagasta on Tue, 15 Sep, arriving in La Serena.Inbound direct flight with JetSmart departs from La Serena on Tue, 22 Sep, arriving in Antofagasta.Price includes taxes and charges.From 52 €, select.
La Serena.52 € per passenger.Departing Fri, 14 Aug, returning Wed, 26 Aug.Return flight with JetSmart.Outbound direct flight with JetSmart departs from Antofagasta on Fri, 14 Aug, arriving in La Serena.Inbound direct flight with JetSmart departs from La Serena on Wed, 26 Aug, arriving in Antofagasta.Price includes taxes and charges.From 52 €, select.
La Serena.53 € per passenger.Departing Fri, 2 Oct, returning Sun, 4 Oct.Return flight with JetSmart.Outbound direct flight with JetSmart departs from Antofagasta on Fri, 2 Oct, arriving in La Serena.Inbound direct flight with JetSmart departs from La Serena on Sun, 4 Oct, arriving in Antofagasta.Price includes taxes and charges.From 53 €, select.
La Serena.53 € per passenger.Departing Sun, 20 Sep, returning Sun, 4 Oct.Return flight with JetSmart.Outbound direct flight with JetSmart departs from Antofagasta on Sun, 20 Sep, arriving in La Serena.Inbound direct flight with JetSmart departs from La Serena on Sun, 4 Oct, arriving in Antofagasta.Price includes taxes and charges.From 53 €, select.
La Serena.71 € per passenger.Departing Mon, 2 Nov, returning Tue, 3 Nov.Return flight with JetSmart.Outbound direct flight with JetSmart departs from Antofagasta on Mon, 2 Nov, arriving in La Serena.Inbound direct flight with JetSmart departs from La Serena on Tue, 3 Nov, arriving in Antofagasta.Price includes taxes and charges.From 71 €, select.
La Serena.74 € per passenger.Departing Thu, 15 Oct, returning Tue, 3 Nov.Return flight with JetSmart.Outbound direct flight with JetSmart departs from Antofagasta on Thu, 15 Oct, arriving in La Serena.Inbound direct flight with JetSmart departs from La Serena on Tue, 3 Nov, arriving in Antofagasta.Price includes taxes and charges.From 74 €, select.
La Serena.74 € per passenger.Departing Wed, 2 Dec, returning Fri, 4 Dec.Return flight with JetSmart.Outbound direct flight with JetSmart departs from Antofagasta on Wed, 2 Dec, arriving in La Serena.Inbound direct flight with JetSmart departs from La Serena on Fri, 4 Dec, arriving in Antofagasta.Price includes taxes and charges.From 74 €, select.
La Serena.80 € per passenger.Departing Tue, 10 Nov, returning Tue, 1 Dec.Return flight with JetSmart.Outbound direct flight with JetSmart departs from Antofagasta on Tue, 10 Nov, arriving in La Serena.Inbound direct flight with JetSmart departs from La Serena on Tue, 1 Dec, arriving in Antofagasta.Price includes taxes and charges.From 80 €, select.
La Serena.84 € per passenger.Departing Wed, 3 Feb, returning Fri, 12 Feb.Return flight with LATAM Airlines.Outbound direct flight with LATAM Airlines departs from Antofagasta on Wed, 3 Feb, arriving in La Serena.Inbound direct flight with LATAM Airlines departs from La Serena on Fri, 12 Feb, arriving in Antofagasta.Price includes taxes and charges.From 84 €, select.
La Serena.87 € per passenger.Departing Mon, 5 Apr, returning Sun, 2 May.Return flight with LATAM Airlines.Outbound direct flight with LATAM Airlines departs from Antofagasta on Mon, 5 Apr, arriving in La Serena.Inbound direct flight with LATAM Airlines departs from La Serena on Sun, 2 May, arriving in Antofagasta.Price includes taxes and charges.From 87 €, select.
La Serena.89 € per passenger.Departing Sat, 2 Jan, returning Mon, 4 Jan.Return flight with LATAM Airlines.Outbound direct flight with LATAM Airlines departs from Antofagasta on Sat, 2 Jan, arriving in La Serena.Inbound direct flight with LATAM Airlines departs from La Serena on Mon, 4 Jan, arriving in Antofagasta.Price includes taxes and charges.From 89 €, select.

Find the cheapest month to fly from Antofagasta to La Serena

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Antofagasta to La Serena flights are currently cheapest in July.
Jul
from 52 €
Aug
from 52 €
Sep
from 52 €
Oct
from 53 €
Nov
from 71 €
Dec
from 74 €
Jan
from 89 €
Feb
from 84 €
Mar
Find prices
Apr
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May
Find prices
Jun
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Direct flights from Antofagasta to La Serena

Antofagasta to La Serena: Alternative routes

Compare routes from Antofagasta to La Serena below. You may find an airport to fly into that's cheaper, faster, or easier than La Serena.

La Serena

5km from central La Serena
ClosestCheapest
from 46 €
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Antofagasta to La Serena: Flight information

The things to know before you go.
Cheapest flight found46 €
Cheapest month to flyJuly
Average flight time1 hr, 28 mins
Most popular airlineJetSmart
Average flights per week31

Finding cheap flights from Antofagasta to La Serena: Frequently asked questions

The best price we found for a return flight from Antofagasta to La Serena is 46 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
1 hour and 28 minutes is the average flight time from Antofagasta to La Serena.
JetSmart, LATAM Airlines and LATAM Airlines Peru fly direct from Antofagasta to La Serena.
As of July 2026, there are 31 flights per week flying from Antofagasta to La Serena.
The cheapest month to fly from Antofagasta to La Serena is usually July.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Antofagasta Airport to La Serena Airport on Monday, 20 July 2026.
Yes – the average flight time is 1 hour and 28 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to La Serena but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to La Serena is around 40 days in advance, so don’t leave your flight to the last minute.

Currently, JetSmart offers the cheapest flight tickets to La Serena.

Travelling from Antofagasta Airport (ANF) to La Serena Airport (LSC): what you need to know

  • Around 1 hour 25 minutes is how long you can expect to be travelling on a direct flight from Antofagasta Airport to La Serena Airport.

  • You can choose from 19 weekly Antofagasta Airport to La Serena Airport flights. The 07:30 departure with Sky Airline is the earliest you can take. JetSMART operates the last service of the day at 19:06.

  • Get to the airport on time so you don't miss your ANF to LSC flight. Be there at least two hours ahead for international flights and an hour early for domestic departures to avoid a last-minute sprint to the gate.

  • Travelling during a peak month like June? Major public holidays and other high seasons can result in longer queues and delays at security. Play it safe and get there up to four hours ahead of international flights and two hours before a domestic departure.

  • A range of airlines operate direct flights from Antofagasta Airport to La Serena Airport, so jetting off to La Serena (and then seeing more of Chile!) is easy. Leading carriers that fly nonstop include:

  • The airline with the highest number of bookings on this route is JetSmart.

  • With an impressive 91.8% of services arriving as planned, LATAM Airlines is the most punctual carrier operating ANF to LSC flights.

  • If you want to explore a new city along the way, consider a flight with a stopover. To see all your options for tickets from Antofagasta Airport to La Serena Airport, deselect 'Direct flights only.' Santiago Arturo Merino Benitez Airport is a well-known stop between ANF and LSC.

How to find the cheapest flights from Antofagasta Airport (ANF) to La Serena Airport (LSC)

  • At the moment, 24 € is the lowest price we've seen for a one-way Antofagasta Airport to La Serena Airport flight. The best price for a return plane ticket is 46 €. Bear in mind that fares may change due to demand when booking.

  • To secure cheap tickets from ANF to LSC, book your journey seven months before your departure.

  • The cheapest month for flights from Antofagasta Airport to La Serena Airport is December. Use the 'Whole month' tool to find the lowest prices if you have flexible travel dates.

  • Save time searching for cheap flights from ANF to LSC by creating a Price Alert. You'll get an email or push notification on the app when a special offer becomes available.

  • Tailor your flights with filters. Choose your ideal arrival and departure times, airlines and total journey duration. You can also sort results by 'Fastest,' 'Cheapest' or 'Best' flights from Antofagasta Airport to La Serena Airport.

Handy information about Antofagasta Airport (ANF)

  • Antofagasta Airport has an excellent on-time record, so you're less likely to experience disruptions. Departures from ANF land at their destination as scheduled 86% of the time.

  • Antofagasta Airport is around 16 kilometres from central Antofagasta. If you're ride-sharing, catching a taxi or driving from the centre, it'll take you 20 minutes or so to get there, depending on the traffic.

  • Taking public transport? You can expect a journey time of around 35 minutes.

  • Want a hotel to stay in before your flight from Antofagasta Airport to La Serena Airport? Check out Hermoso Departamento con Laguna Navegable. Enjoy a good night's rest here before heading to ANF.

Arriving at La Serena Airport (LSC)

  • If you're arriving on a late Antofagasta Airport to La Serena Airport flight, nothing beats the convenience of staying near the terminal. Grab your bags from the carousel and then be showered and relaxing shortly after at one of these accommodation options near LSC:

  • Hit the road running by picking up a La Serena Airport rental car. Grab your wheels from Street Rent a Car, gama or Budget and explore beyond La Serena's main sights.

  • Lock in the best rate by reserving your vehicle from La Serena Airport around two weeks before your departure date.

When to fly to La Serena Airport (LSC)

  • It's time to work out your dates for your flight from Antofagasta Airport to La Serena Airport. June is the busiest month to head to La Serena. If you want a quieter vibe, go in March.

  • When booking your flight from Antofagasta Airport to La Serena Airport, consider the kind of weather you enjoy. February is the warmest month in La Serena, with the temperature ranging from 14ºC (57ºF) to 24ºC (75ºF).

  • If you want cooler conditions, search for a cheap ticket from ANF to LSC in July. Average temperatures are between 8ºC (46ºF) and 20ºC (68ºF) then.

Explore more of Chile

  • You've visited La Serena, now it's time to explore other parts of Chile. Journey around 402 kilometres south to Santiago to tick off its popular sights. From Gran Torre Santiago to Museo de la Memoria y los Derechos Humanos and Fundación Pablo Neruda, you've got a jam-packed schedule ahead.

  • If you're looking to explore another great destination in Chile, consider Vina del Mar, roughly 354 kilometres south of La Serena. Reñaca beach, Playa El Sol and Playa Blanca are key highlights.

Plan the rest of your trip from Antofagasta to La Serena

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.