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465 € Cheap Flights from Chicago to Panama City

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Flight deals from Chicago to Panama City

Looking for a cheap last-minute deal or the best return flight from Chicago to Panama City? If you want to travel next month, return fares start from 485 €. Find the lowest prices on one-way and return tickets right here.
Panama City.465 € per passenger.Departing Sat, 22 Aug, returning Sat, 5 Sep.Return flight with LATAM Airlines and Avianca.Outbound indirect flight with LATAM Airlines, departs from Chicago O'Hare International on Sat, 22 Aug, arriving in Balboa.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Sat, 5 Sep, arriving in Chicago O'Hare International.Price includes taxes and charges.From 465 €, select.
Panama City.485 € per passenger.Departing Thu, 20 Aug, returning Wed, 26 Aug.Return flight with LATAM Airlines and Avianca.Outbound indirect flight with LATAM Airlines, departs from Chicago O'Hare International on Thu, 20 Aug, arriving in Balboa.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Wed, 26 Aug, arriving in Chicago O'Hare International.Price includes taxes and charges.From 485 €, select.
Panama City.490 € per passenger.Departing Sat, 19 Sep, returning Sat, 26 Sep.Return flight with jetBlue and Avianca.Outbound indirect flight with jetBlue, departs from Chicago O'Hare International on Sat, 19 Sep, arriving in Balboa.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Sat, 26 Sep, arriving in Chicago O'Hare International.Price includes taxes and charges.From 490 €, select.
Panama City.520 € per passenger.Departing Tue, 29 Sep, returning Tue, 13 Oct.Return flight with LATAM Airlines and Avianca.Outbound indirect flight with LATAM Airlines, departs from Chicago Midway on Tue, 29 Sep, arriving in Balboa.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 13 Oct, arriving in Chicago Rockford.Price includes taxes and charges.From 520 €, select.
Panama City.537 € per passenger.Departing Wed, 29 Jul, returning Wed, 26 Aug.Return flight with Frontier Airlines and Avianca.Outbound indirect flight with Frontier Airlines, departs from Chicago O'Hare International on Wed, 29 Jul, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Wed, 26 Aug, arriving in Chicago O'Hare International.Price includes taxes and charges.From 537 €, select.
Panama City.572 € per passenger.Departing Thu, 5 Nov, returning Mon, 9 Nov.Return flight with Allegiant Air and Avianca.Outbound indirect flight with Allegiant Air, departs from Chicago Rockford on Thu, 5 Nov, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 9 Nov, arriving in Chicago Midway.Price includes taxes and charges.From 572 €, select.
Panama City.586 € per passenger.Departing Wed, 21 Oct, returning Mon, 26 Oct.Return flight with Frontier Airlines and Copa.Outbound indirect flight with Frontier Airlines, departs from Chicago Midway on Wed, 21 Oct, arriving in Panama City Tocumen International.Inbound indirect flight with Copa, departs from Panama City Tocumen International on Mon, 26 Oct, arriving in Chicago O'Hare International.Price includes taxes and charges.From 586 €, select.
Panama City.608 € per passenger.Departing Sun, 26 Jul, returning Tue, 28 Jul.Return flight with Allegiant Air and Avianca.Outbound indirect flight with Allegiant Air, departs from Chicago Rockford on Sun, 26 Jul, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 28 Jul, arriving in Chicago Rockford.Price includes taxes and charges.From 608 €, select.
Panama City.610 € per passenger.Departing Mon, 15 Feb, returning Sat, 27 Feb.Return flight with LATAM Airlines and Copa.Outbound indirect flight with LATAM Airlines, departs from Chicago O'Hare International on Mon, 15 Feb, arriving in Balboa.Inbound indirect flight with Copa, departs from Panama City Tocumen International on Sat, 27 Feb, arriving in Chicago O'Hare International.Price includes taxes and charges.From 610 €, select.
Panama City.644 € per passenger.Departing Mon, 18 Jan, returning Sun, 24 Jan.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Mon, 18 Jan, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sun, 24 Jan, arriving in Chicago O'Hare International.Price includes taxes and charges.From 644 €, select.
Panama City.644 € per passenger.Departing Wed, 21 Oct, returning Wed, 28 Oct.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Wed, 21 Oct, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Wed, 28 Oct, arriving in Chicago O'Hare International.Price includes taxes and charges.From 644 €, select.
Panama City.644 € per passenger.Departing Thu, 29 Apr, returning Sat, 8 May.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Thu, 29 Apr, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sat, 8 May, arriving in Chicago O'Hare International.Price includes taxes and charges.From 644 €, select.
Panama City.644 € per passenger.Departing Fri, 11 Dec, returning Fri, 18 Dec.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Fri, 11 Dec, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Fri, 18 Dec, arriving in Chicago O'Hare International.Price includes taxes and charges.From 644 €, select.
Panama City.644 € per passenger.Departing Sat, 30 Jan, returning Sat, 13 Feb.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Sat, 30 Jan, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Sat, 13 Feb, arriving in Chicago O'Hare International.Price includes taxes and charges.From 644 €, select.
Panama City.644 € per passenger.Departing Mon, 1 Feb, returning Mon, 8 Feb.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Mon, 1 Feb, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Mon, 8 Feb, arriving in Chicago O'Hare International.Price includes taxes and charges.From 644 €, select.
Panama City.644 € per passenger.Departing Fri, 6 Nov, returning Mon, 9 Nov.Return flight with Copa.Outbound direct flight with Copa departs from Chicago O'Hare International on Fri, 6 Nov, arriving in Panama City Tocumen International.Inbound direct flight with Copa departs from Panama City Tocumen International on Mon, 9 Nov, arriving in Chicago O'Hare International.Price includes taxes and charges.From 644 €, select.

Find the cheapest month to fly from Chicago to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Chicago to Panama City flights are currently cheapest in August.
Jul
from 608 €
Aug
from 485 €
Sep
from 490 €
Oct
from 586 €
Nov
from 572 €
Dec
from 644 €
Jan
from 644 €
Feb
from 610 €
Mar
from 646 €
Apr
Find prices
May
from 646 €
Jun
Find prices

Direct flights from Chicago to Panama City

Alternative Chicago to Panama City routes

Looking for the cheapest, fastest or easiest route from Chicago to Panama City? You could fly into the following airports instead.

Panama City Paitilla

5km from central Panama City
Closest
from 1.334 €
Search flights

Balboa

5km from central Panama City
from 571 €
Search flights

Panama City Tocumen International

18km from central Panama City
Cheapest
from 484 €
Search flights

Chicago to Panama City: Flight information

The things to know before you go.
Cheapest flight found465 €
Cheapest month to flyAugust
Average flight time5 hrs, 23 mins
Most popular airlineCopa
Average flights per week41

Finding cheap flights from Chicago to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a return flight from Chicago to Panama City is 465 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
5 hours and 23 minutes is the average flight time from Chicago to Panama City.
Copa, United and EVA Air fly direct from Chicago to Panama City.
As of July 2026, there are 41 flights per week flying from Chicago to Panama City.
The cheapest month to fly from Chicago to Panama City is usually August.
If you're flying from Chicago, the cheapest airport near Panama City is Balboa – which is 4.9 km away from the centre of Panama City. We've found flights into this airport from 465 €.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Chicago to Panama City on Saturday, 22 August 2026.
Yes – the average flight time is 5 hours and 23 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.

In July, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
The cheapest airline that flies to Panama City is LATAM Airlines. And the cheapest airline that flies to Balboa Airport is Copa.

Flying from Chicago to Panama City: what you need to know

  • Chicago is home to a couple of airports that could be the jumping-off point for your adventure. Check out your options for booking a flight from Chicago to Panama City flying out of Chicago O'Hare International Airport (ORD) or Chicago Midway Airport (MDW).

  • Panama City Tocumen International Airport (PTY) and Balboa Airport (BLB) are Panama City's primary gateways.

  • Around 5 hours 25 minutes is how long you can expect to be travelling on a direct Chicago to Panama City flight.

  • The timezone in Panama City is UTC-5, which is one hour ahead of Chicago.

  • With 14 weekly flights between the two airports, Chicago O'Hare International Airport (ORD) to Panama City Tocumen International Airport (PTY) is the busiest route. Hop on the first flight from Chicago to Panama City with Copa Airlines at 01:07. If you prefer to make the most of your day before jetting off, the latest departure from ORD to PTY is with Copa Airlines at 15:10.

  • For a relaxed travel experience, turn up at the airport two hours ahead of international flights and one hour before domestic departures. This will give you enough time to catch your Chicago to Panama City flight.

  • You can expect bigger queues during popular months such as July. Arriving up to four hours in advance for international flights and two hours for domestic departures will give you plenty of time for security and boarding.

How to find the cheapest flights from Chicago to Panama City

  • To snag cheap Chicago to Panama City flights, book your journey one month ahead of your departure.

  • June is the best month for nabbing a fantastic deal on a plane ticket from Chicago to Panama City. If you're looking to travel during a different time of year, the 'Whole month' tool will give you the lowest prices across every month.

  • Cut down on the time spent looking for cheap flights from Chicago to Panama City by setting up a Price Alert. You'll receive an email or push notification on the app when a special offer becomes available.

  • Tailor your flights using filters. Choose your ideal arrival and departure times, airlines and total journey duration. You can also sort your results by 'Cheapest,' 'Best' or 'Fastest' Chicago to Panama City flights.

Flying from Chicago

Chicago O'Hare International Airport (ORD)

  • If you're searching for a direct flight from Chicago to Panama City, you can depart from Chicago O'Hare International Airport (ORD). Travel from ORD to Panama City Tocumen International Airport (PTY) in one seamless trip.

  • Reserve your Chicago to Panama City plane tickets with Copa Airlines. This airline is a popular option for direct flights from ORD.

  • A stopover is the ideal opportunity to break up your trip — and maybe even tour another city. When searching for Chicago to Panama City flights departing from Chicago O'Hare International Airport, uncheck the 'Direct flights only' box to see where you can visit along the way. Top options include:

    • Atlanta Hartsfield-Jackson Airport (ATL)

    • Miami International Airport (MIA)

    • Raleigh / Durham Airport (RDU)

  • Located around 26 kilometres from central Chicago, ORD can be reached in about 30 minutes by car (depending on traffic). The journey by public transport is roughly 45 minutes.

  • After a stress-free start to your trip? Stay near Chicago O'Hare International Airport. Whether you're taking an early flight from Chicago to Panama City or want to avoid feeling rushed, these hotels are ideal:

  • Of all flights departing from Chicago O'Hare International Airport, 70% arrive on time at their destination.

  • The address for ORD is 10000 West O'Hare.

Chicago Midway Airport (MDW)

  • Visit friends or family or just take a moment to stretch your legs with a stopover. If you'd like to split up your Chicago to Panama City flight, check out these options when setting off from Chicago Midway Airport:

    • Atlanta Hartsfield-Jackson Airport (ATL)

    • Orlando International Airport (MCO)

    • Raleigh / Durham Airport (RDU)

  • You can get to MDW from central Chicago in about 25 minutes by car (depending on traffic conditions). The journey by public transport will take roughly 30 minutes to cover the 14 kilometres or so.

  • Get your holiday started early with an additional night away from home. Before your flight from Chicago to Panama City, kick back in one of these hotels close to Chicago Midway Airport:

  • When it comes to flights staying on schedule, Chicago Midway Airport has an on-time arrival rate of 76%.

  • The street address for MDW is 5700 South Cicero.

Arriving in Panama City

Panama City Tocumen International Airport (PTY)

  • Panama City Tocumen International Airport (PTY) is approximately 18 kilometres from central Panama City. If you're catching a taxi or a ride-share, the drive takes roughly 35 minutes.

  • Getting to the centre on public transport takes about 50 minutes.

  • The last thing you want is a long journey to your hotel if you're getting in late on a flight from Chicago to Panama City. Book one of these accommodation options near PTY instead:

  • Hit the road running by picking up a Panama City Tocumen International Airport rental car. Grab your wheels from Avis, Dollar or MEX and experience the lesser-explored corners of Panama City and beyond.

  • Lock in the best possible rate by booking your vehicle from Panama City Tocumen International Airport around three weeks before your departure date.

Panama City Paitilla Airport (PAC)

  • Central Panama City is approximately 5 kilometres from Panama City Paitilla Airport (PAC). Step off your flight from Chicago to Panama City and then keep a lookout for any airport signs that'll help you reach the city centre.

  • You'll find some comfortable places to lay your head close to PAC. Settle in and get cosy after your Chicago to Panama City flight at any of these perfectly located options:

  • Thrifty, Avis and Alamo make picking up a Panama City Paitilla Airport rental car quick and easy. These providers are located around or in the terminal and will have you on your way in a heartbeat.

  • Snap up the best price by reserving your ride from PAC three weeks in advance. You'll also have access to a bigger selection of vehicles.

Balboa Airport (BLB)

  • Head to the city centre after your flight from Chicago to Panama City has arrived. Central Panama City is around 5 kilometres from Balboa Airport (BLB) and takes roughly 10 minutes to get to by car.

  • The journey takes roughly 20 minutes when travelling on public transport.

  • Whether you're looking for a zippy compact for a solo trip or an SUV to move the whole family, you'll find the perfect Balboa Airport rental car for you. Check out wheels available from providers such as Sixt, Dollar and Thrifty.

  • Around one week ahead of your flight from Chicago to Panama City is a good time to secure your vehicle from BLB. You're more likely to get a better rate or even pick up some early bird discounts.

Best time to go to Panama City

  • March is the quietest month for flights from Chicago to Panama City, while July is the most popular. Pick the ideal time to visit Panama City based on whether you want a laid-back vibe or a more bustling atmosphere.

  • When booking your Chicago to Panama City tickets, consider the weather you're most comfortable in. March is the warmest month in Panama City, with temperatures ranging from 21ºC (70ºF) to 32ºC (90ºF).

  • For cooler conditions, search for a cheap flight from Chicago to Panama City in January when temperatures average between 22ºC (72ºF) and 31ºC (88ºF).

More about Panama City

  • Start your Panama City trip right by choosing the ideal place to stay. As soon as you've booked your flight from Chicago to Panama City, explore our selection of accommodation options including:

  • San Felipe and Metropolitan Cathedral Basilica of Santa Maria the Ancient are a couple of top attractions to put on your Panama City must-do list. Keep the sightseeing going at Independence Square.

Plan the rest of your trip from Chicago to Panama City

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.