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272 € Cheap Flights from Cali to Guayaquil

Compare Cali to Guayaquil flight deals

Find the cheapest month or even day of the year to fly to Guayaquil

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Flight deals from Cali to Guayaquil

Looking for a cheap last-minute deal or the best return flight from Cali Airport to Guayaquil Airport? If you want to travel next month, return fares start from 335 €. Find the lowest prices on one-way and return tickets right here.
Guayaquil.272 € per passenger.Departing Thu, 16 Jul, returning Sat, 18 Jul.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Cali on Thu, 16 Jul, arriving in Guayaquil.Inbound indirect flight with Avianca, departs from Guayaquil on Sat, 18 Jul, arriving in Cali.Price includes taxes and charges.From 272 €, select.
Guayaquil.293 € per passenger.Departing Thu, 17 Sep, returning Sun, 20 Sep.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Cali on Thu, 17 Sep, arriving in Guayaquil.Inbound indirect flight with Avianca, departs from Guayaquil on Sun, 20 Sep, arriving in Cali.Price includes taxes and charges.From 293 €, select.
Guayaquil.295 € per passenger.Departing Fri, 6 Nov, returning Sat, 7 Nov.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Cali on Fri, 6 Nov, arriving in Guayaquil.Inbound indirect flight with Avianca, departs from Guayaquil on Sat, 7 Nov, arriving in Cali.Price includes taxes and charges.From 295 €, select.
Guayaquil.330 € per passenger.Departing Thu, 30 Jul, returning Sun, 2 Aug.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Cali on Thu, 30 Jul, arriving in Guayaquil.Inbound indirect flight with Avianca, departs from Guayaquil on Sun, 2 Aug, arriving in Cali.Price includes taxes and charges.From 330 €, select.
Guayaquil.334 € per passenger.Departing Mon, 28 Sep, returning Fri, 16 Oct.Return flight with Copa.Outbound indirect flight with Copa, departs from Cali on Mon, 28 Sep, arriving in Guayaquil.Inbound indirect flight with Copa, departs from Guayaquil on Fri, 16 Oct, arriving in Cali.Price includes taxes and charges.From 334 €, select.
Guayaquil.335 € per passenger.Departing Sun, 9 Aug, returning Wed, 19 Aug.Return flight with Copa.Outbound indirect flight with Copa, departs from Cali on Sun, 9 Aug, arriving in Guayaquil.Inbound indirect flight with Copa, departs from Guayaquil on Wed, 19 Aug, arriving in Cali.Price includes taxes and charges.From 335 €, select.
Guayaquil.336 € per passenger.Departing Tue, 13 Oct, returning Sat, 17 Oct.Return flight with Copa.Outbound indirect flight with Copa, departs from Cali on Tue, 13 Oct, arriving in Guayaquil.Inbound indirect flight with Copa, departs from Guayaquil on Sat, 17 Oct, arriving in Cali.Price includes taxes and charges.From 336 €, select.
Guayaquil.337 € per passenger.Departing Thu, 7 Jan, returning Mon, 11 Jan.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Cali on Thu, 7 Jan, arriving in Guayaquil.Inbound indirect flight with LATAM Airlines, departs from Guayaquil on Mon, 11 Jan, arriving in Cali.Price includes taxes and charges.From 337 €, select.
Guayaquil.339 € per passenger.Departing Tue, 22 Dec, returning Tue, 12 Jan.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Cali on Tue, 22 Dec, arriving in Guayaquil.Inbound indirect flight with LATAM Airlines, departs from Guayaquil on Tue, 12 Jan, arriving in Cali.Price includes taxes and charges.From 339 €, select.
Guayaquil.340 € per passenger.Departing Mon, 17 May, returning Mon, 31 May.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Cali on Mon, 17 May, arriving in Guayaquil.Inbound indirect flight with Avianca, departs from Guayaquil on Mon, 31 May, arriving in Cali.Price includes taxes and charges.From 340 €, select.
Guayaquil.341 € per passenger.Departing Tue, 1 Jun, returning Wed, 16 Jun.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Cali on Tue, 1 Jun, arriving in Guayaquil.Inbound indirect flight with Avianca, departs from Guayaquil on Wed, 16 Jun, arriving in Cali.Price includes taxes and charges.From 341 €, select.
Guayaquil.362 € per passenger.Departing Tue, 22 Dec, returning Thu, 24 Dec.Return flight with LATAM Airlines.Outbound indirect flight with LATAM Airlines, departs from Cali on Tue, 22 Dec, arriving in Guayaquil.Inbound indirect flight with LATAM Airlines, departs from Guayaquil on Thu, 24 Dec, arriving in Cali.Price includes taxes and charges.From 362 €, select.

Find the cheapest month to fly from Cali to Guayaquil

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Cali to Guayaquil flights are currently cheapest in July.
Jul
from 272 €
Aug
from 335 €
Sep
from 293 €
Oct
from 336 €
Nov
from 295 €
Dec
from 362 €
Jan
from 337 €
Feb
Find prices
Mar
Find prices
Apr
Find prices
May
from 340 €
Jun
from 341 €

Cali to Guayaquil: Alternative routes

Compare routes from Cali to Guayaquil below. You may find an airport to fly into that's cheaper, faster, or easier than Guayaquil.

Guayaquil

4km from central Guayaquil
ClosestCheapest
from 272 €
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Cali to Guayaquil: Flight information

The things to know before you go.
Cheapest flight found272 €
Cheapest month to flyJuly

Finding cheap flights from Cali to Guayaquil: Frequently asked questions

The best price we found for a return flight from Cali to Guayaquil is 272 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Cali to Guayaquil. But we found flights with one or more stops from 272 €.
As of July 2026, there are no flights flying from Cali to Guayaquil.
The cheapest month to fly from Cali to Guayaquil is usually July.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Cali Airport to Guayaquil Airport on Thursday, 16 July 2026.
No airlines currently offer direct flights between Cali Airport and Guayaquil Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Guayaquil but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Guayaquil is around 40 days in advance, so don’t leave your flight to the last minute.

Currently, Avianca offers the cheapest flight tickets to Guayaquil.

Flying from Cali Airport (CLO) to Guayaquil Airport (GYE): what you need to know

  • Cali and Guayaquil share the same timezone, UTC-5.

  • Your CLO to GYE flight won't wait if you're late, so show up at the airport on time. Arrive up to one hour in advance for domestic flights and two hours ahead for international travel.

  • During popular months such as January, it's best to get to the airport even earlier. Plan to arrive two hours before domestic departures and four hours ahead for international flights whenever you're flying during peak periods in general.

  • If you'd like to split up your journey, just uncheck 'Direct flights only' when searching for your ticket from Cali Airport to Guayaquil Airport. These are the most popular stopovers between CLO and GYE:

    • Miami International Airport

    • Bogota Airport

    • Panama City Tocumen International Airport

How to find the cheapest flights from Cali Airport (CLO) to Guayaquil Airport (GYE)

  • At the moment, 175 € is the cheapest price we've seen for a one-way Cali Airport to Guayaquil Airport flight. The best price for a return plane ticket is 272 €. Remember that fares may change due to availability when booking.

  • To pick up cheap tickets from CLO to GYE, book in advance. Airlines typically offer their best fares when flights are first made available.

  • If you're flexible with your travel dates, try using the 'Whole month' search tool. It'll give you the lowest price across the month when looking for a flight from Cali Airport to Guayaquil Airport.

  • You don't need to check every day to find out if fares have dropped when you set up a Price Alert. We'll let you know the moment there's a better deal on cheap flights from CLO to GYE.

  • Lock in the right flight for you with the help of the filters. To see the 'Best,' 'Cheapest' or 'Fastest' flights from Cali Airport to Guayaquil Airport, use the 'Sort by' function. You can also filter results by arrival and departure times, airline, and number of stops.

Handy information about Cali Airport (CLO)

  • 72% of flights that take off from Cali Airport touch down at their destination on time.

  • Cali Airport is around 21 kilometres from central Cali. If you're ride-sharing, catching a taxi or driving from the centre, it'll take you 30 minutes or so to get there, depending on the traffic.

  • The trip on public transport typically takes 50 minutes.

  • If you've booked an early flight from Cali Airport to Guayaquil Airport, why not stay close by? Avoid the hassle of rushing to the airport (and enjoy some extra shut-eye) at Hotel Real Elim International. Hotel Sin Escala is another handy accommodation option near CLO.

Arriving at Guayaquil Airport (GYE)

  • If you have a late Cali Airport to Guayaquil Airport flight, nothing beats the convenience of staying close to the terminal. Pick up your bags from the carousel and then be showered and relaxing soon after at one of these options near GYE:

  • Grab a Guayaquil Airport rental car and explore Guayaquil and beyond with your own wheels. Europcar, Keddy By Europcar and Goldcar are popular providers to choose from here.

  • Reserving your ride from Guayaquil Airport about four weeks in advance can help you secure the lowest rate.

When to fly to Guayaquil Airport (GYE)

  • July is the most popular month for flights from Cali Airport to Guayaquil Airport. To escape the crowds, head to Guayaquil in March.

  • When reserving your flight from Cali Airport to Guayaquil Airport, consider the type of weather you like. November is the warmest month in Guayaquil, with temperatures ranging from 19ºC (66ºF) to 33ºC (91ºF).

  • August sees average temperatures of between 19ºC (66ºF) and 32ºC (90ºF). Search for cheap tickets from CLO to GYE around that time if you want to travel when it's cooler.

Explore more of Ecuador

  • You've visited Guayaquil, now it's time to discover other corners of Ecuador. Travel about 274 kilometres north-east to Quito to check off its leading sights. From Quito Historic Centre to Catedral Metropolitana de Quito and Camino de los Incas, you'll have a full itinerary ahead.

  • Around 129 kilometres south-east of Guayaquil, Cuenca is another favourite stop in Ecuador. Experience the best of this destination with a visit to Inca Ruins, New Cathedral (Catedral de la Immaculada) and Old Cathedral of Cuenca.

Plan the rest of your trip from Cali to Guayaquil

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.