Skyscanner home

528 € Cheap Flights from Columbus to Panama City

Compare Columbus to Panama City flight deals

Find the cheapest month or even day of the year to fly to Panama City

Book the best Panama City fare with no extra fees

Flight deals from Columbus to Panama City

Looking for a cheap last-minute deal or the best return flight from Columbus to Panama City? If you want to travel next month, return fares start from 528 €. Find the lowest prices on one-way and return tickets right here.
Panama City.528 € per passenger.Departing Wed, 16 Sep, returning Tue, 22 Sep.Return flight with Delta.Outbound indirect flight with Delta, departs from Port Columbus on Wed, 16 Sep, arriving in Panama City Tocumen International.Inbound indirect flight with Delta, departs from Panama City Tocumen International on Tue, 22 Sep, arriving in Port Columbus.Price includes taxes and charges.From 528 €, select.
Panama City.528 € per passenger.Departing Tue, 11 Aug, returning Tue, 18 Aug.Return flight with Delta.Outbound indirect flight with Delta, departs from Port Columbus on Tue, 11 Aug, arriving in Panama City Tocumen International.Inbound indirect flight with Delta, departs from Panama City Tocumen International on Tue, 18 Aug, arriving in Port Columbus.Price includes taxes and charges.From 528 €, select.
Panama City.529 € per passenger.Departing Wed, 17 Feb, returning Wed, 24 Feb.Return flight with United.Outbound indirect flight with United, departs from Port Columbus on Wed, 17 Feb, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Wed, 24 Feb, arriving in Port Columbus.Price includes taxes and charges.From 529 €, select.
Panama City.529 € per passenger.Departing Tue, 29 Sep, returning Thu, 1 Oct.Return flight with Delta.Outbound indirect flight with Delta, departs from Port Columbus on Tue, 29 Sep, arriving in Panama City Tocumen International.Inbound indirect flight with Delta, departs from Panama City Tocumen International on Thu, 1 Oct, arriving in Port Columbus.Price includes taxes and charges.From 529 €, select.
Panama City.530 € per passenger.Departing Tue, 6 Oct, returning Tue, 20 Oct.Return flight with United.Outbound indirect flight with United, departs from Port Columbus on Tue, 6 Oct, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Tue, 20 Oct, arriving in Port Columbus.Price includes taxes and charges.From 530 €, select.
Panama City.558 € per passenger.Departing Sat, 31 Oct, returning Fri, 6 Nov.Return flight with United.Outbound indirect flight with United, departs from Port Columbus on Sat, 31 Oct, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Fri, 6 Nov, arriving in Port Columbus.Price includes taxes and charges.From 558 €, select.
Panama City.579 € per passenger.Departing Wed, 29 Jul, returning Tue, 4 Aug.Return flight with United.Outbound indirect flight with United, departs from Port Columbus on Wed, 29 Jul, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Tue, 4 Aug, arriving in Port Columbus.Price includes taxes and charges.From 579 €, select.
Panama City.594 € per passenger.Departing Wed, 22 Jul, returning Fri, 31 Jul.Return flight with United.Outbound indirect flight with United, departs from Port Columbus on Wed, 22 Jul, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Fri, 31 Jul, arriving in Port Columbus.Price includes taxes and charges.From 594 €, select.
Panama City.710 € per passenger.Departing Mon, 8 Mar, returning Sat, 13 Mar.Return flight with Delta.Outbound indirect flight with Delta, departs from Port Columbus on Mon, 8 Mar, arriving in Panama City Tocumen International.Inbound indirect flight with Delta, departs from Panama City Tocumen International on Sat, 13 Mar, arriving in Port Columbus.Price includes taxes and charges.From 710 €, select.
Panama City.892 € per passenger.Departing Wed, 16 Dec, returning Thu, 24 Dec.Return flight with jetBlue and Copa.Outbound indirect flight with jetBlue, departs from Port Columbus on Wed, 16 Dec, arriving in Balboa.Inbound indirect flight with Copa, departs from Panama City Tocumen International on Thu, 24 Dec, arriving in Columbus Rickenbacker.Price includes taxes and charges.From 892 €, select.
Panama City.1.030 € per passenger.Departing Tue, 22 Dec, returning Tue, 5 Jan.Return flight with jetBlue and Copa.Outbound indirect flight with jetBlue, departs from Port Columbus on Tue, 22 Dec, arriving in Panama City Tocumen International.Inbound indirect flight with Copa, departs from Panama City Tocumen International on Tue, 5 Jan, arriving in Port Columbus.Price includes taxes and charges.From 1.030 €, select.
Panama City.1.184 € per passenger.Departing Wed, 25 Nov, returning Sun, 29 Nov.Return flight with United.Outbound indirect flight with United, departs from Port Columbus on Wed, 25 Nov, arriving in Panama City Tocumen International.Inbound indirect flight with United, departs from Panama City Tocumen International on Sun, 29 Nov, arriving in Port Columbus.Price includes taxes and charges.From 1.184 €, select.

Find the cheapest month to fly from Columbus to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Columbus to Panama City flights are currently cheapest in August.
Jul
from 594 €
Aug
from 528 €
Sep
from 528 €
Oct
from 530 €
Nov
from 1.184 €
Dec
from 892 €
Jan
Find prices
Feb
from 529 €
Mar
from 710 €
Apr
Find prices
May
Find prices
Jun
Find prices

Alternative Columbus to Panama City routes

Looking for the cheapest, fastest or easiest route from Columbus to Panama City? You could fly into the following airports instead.

Panama City Paitilla

5km from central Panama City
Closest
from 1.275 €
Search flights

Balboa

5km from central Panama City
from 880 €
Search flights

Panama City Tocumen International

18km from central Panama City
Cheapest
from 528 €
Search flights

Columbus to Panama City: Flight information

The things to know before you go.
Cheapest flight found528 €
Cheapest month to flySeptember

Finding cheap flights from Columbus to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a return flight from Columbus to Panama City is 528 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Columbus to Panama City. But we found flights with one or more stops from 528 €.
As of July 2026, there are no flights flying from Columbus to Panama City.
The cheapest month to fly from Columbus to Panama City is usually September.
If you're flying from Columbus, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from 528 €.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Columbus to Panama City on Wednesday, 16 September 2026.
No airlines currently offer direct flights between Columbus and Panama City. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.

In July, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
The cheapest airline that flies to Panama City is Delta .

Travelling from Columbus to Panama City: what you need to know

  • Columbus's main base, Port Columbus Airport (CMH), is where countless awesome holidays begin. Explore the departure options from here when searching for a flight from Columbus to Panama City.

  • Panama City Tocumen International Airport (PTY) and Balboa Airport (BLB) are Panama City's major gateways.

  • Panama City's timezone is UTC-5, which is the same as Columbus.

  • For stress-free travel, turn up at the airport two hours ahead of international flights and an hour before domestic departures. This will give you enough time to catch your Columbus to Panama City flight.

  • Flying during a popular month like July? School holidays and other high seasons can lead to longer lines at security. Play things extra safe and arrive up to four hours before international flights and two hours before domestic departures.

How to find the cheapest flights from Columbus to Panama City

  • To pick up cheap Columbus to Panama City flights, book as early as possible. Airlines usually offer lower fares when tickets are first released.

  • Finding cheap plane tickets from Columbus to Panama City is more likely if you're flexible with your travel dates. Use the 'Whole month' search tool to see the lowest fares across each month and snap up a fantastic deal.

  • Finding a cheap flight from Columbus to Panama City is a breeze with Price Alerts. Simply set up one of these automatic alerts and we'll notify you when there's a better deal.

  • Save money on your Columbus to Panama City flight with the help of our filters. Select your ideal times, number of stops and airlines, then sort the results by 'Cheapest' for the best deals.

Flying from Columbus

Port Columbus Airport (CMH)

  • Stopovers are the perfect opportunity to take a travel break — and maybe even visit a new city. When browsing Columbus to Panama City flights departing from Port Columbus Airport, uncheck the 'Direct flights only' box to see where you can stop along the way. Here are some options to consider:

    • Atlanta Hartsfield-Jackson Airport (ATL)

    • Fort Lauderdale International Airport (FLL)

    • Cancun Airport (CUN)

  • CMH is about 10 kilometres from central Columbus. If you're ride-sharing, catching a taxi or driving from the centre, it'll take you 20 minutes or so to get there, depending on the traffic. If you're taking public transport, expect the trip time to be around 40 minutes.

  • Planning to catch an early flight from Columbus to Panama City? Avoid the last-minute rush to the terminal (and sneak in some extra precious sleep) by choosing one of these hotels near Port Columbus Airport:

  • When it comes to the on-time performance of Port Columbus Airport, data shows 77% of flights arrive within the scheduled time frame.

  • You'll find CMH at 4600 International Gateway.

Arriving in Panama City

Panama City Tocumen International Airport (PTY)

  • Panama City Tocumen International Airport (PTY) to central Panama City takes around 35 minutes by car. The centre is roughly 18 kilometres away.

  • When travelling on public transport, expect a journey time of about 50 minutes.

  • The last thing you want is a long journey to your hotel if you're arriving on a late flight from Columbus to Panama City. Reserve one of these accommodation options near PTY instead:

  • Explore without limits with a Panama City Tocumen International Airport rental car. Pick up a set of wheels from Avis, Dollar or MEX and see more of Panama City and beyond.

  • To get the best deal, book your vehicle from Panama City Tocumen International Airport around three weeks ahead of your Columbus to Panama City flight.

Panama City Paitilla Airport (PAC)

  • If you're staying in Panama City's centre (or just want to start sightseeing straight away), the city is around 5 kilometres from Panama City Paitilla Airport (PAC). Look for any information desks to get directions after hopping off your flight from Columbus to Panama City.

  • There are some comfortable places ready to welcome you near PAC. Settle in and get cosy after your Columbus to Panama City flight at one of these well-located options:

  • Forget about inconvenient public transport timetables or taxi lines. Pick up a Panama City Paitilla Airport rental car and take your trip in whatever direction you choose. Compare rates and availability from Thrifty, Avis and Alamo.

  • Snap up the best price by reserving your ride from PAC three weeks in advance. You'll also have access to a bigger selection of vehicles.

Balboa Airport (BLB)

  • Head to the city centre after your flight from Columbus to Panama City has arrived. Central Panama City is around 5 kilometres from Balboa Airport (BLB) and takes roughly 10 minutes to reach by taxi or ride-share.

  • Public transport can get you there in roughly 20 minutes.

  • Whether you're after a zippy compact just for you or a roomy SUV to fit the family, you'll find the perfect Balboa Airport rental car for you. Browse wheels available here from providers such as Sixt, Dollar and Thrifty.

  • If you're looking for a vehicle with specific features, book your ride from BLB about one week before your flight from Columbus to Panama City. This improves your chances of getting the car you want, as well as a better price.

Best time to go to Panama City

  • It's time to figure out your dates for your flight from Columbus to Panama City. July is the most popular month for a trip to Panama City. If you want a quieter atmosphere, go in March.

  • The warmest month in Panama City is March, with temperatures ranging between 21ºC (70ºF) and 32ºC (90ºF). Lock in your Columbus to Panama City ticket then if that's your idea of comfortable weather.

  • January sees average temperatures of between 22ºC (72ºF) and 31ºC (88ºF). Search for cheap flights from Columbus to Panama City around that time if you'd rather travel in cooler conditions.

More about Panama City

  • After booking your flight from Columbus to Panama City, find a hotel that offers the right mix of comfort and location. Make one of these options your base for exploring Panama City:

  • There are so many things to explore in this city it can be tricky to work out where to start. San Felipe, Metropolitan Cathedral Basilica of Santa Maria the Ancient and Independence Square are top sights which should feature on any good Panama City itinerary.

Plan the rest of your trip from Columbus to Panama City

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.