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174 € Cheap Flights from Des Moines to San Francisco International

Compare Des Moines to San Francisco International flight deals

Find the cheapest month or even day of the year to fly to San Francisco International

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Flight deals from Des Moines to San Francisco International

Looking for a cheap last-minute deal or the best return flight from Des Moines Airport to San Francisco International Airport? If you want to travel next month, return fares start from 174 €. Find the lowest prices on one-way and return tickets right here.
San Francisco.174 € per passenger.Departing Mon, 17 Aug, returning Thu, 20 Aug.Return flight with Allegiant Air and Frontier Airlines.Outbound indirect flight with Allegiant Air, departs from Des Moines on Mon, 17 Aug, arriving in San Francisco International.Inbound indirect flight with Frontier Airlines, departs from San Francisco International on Thu, 20 Aug, arriving in Des Moines.Price includes taxes and charges.From 174 €, select.
San Francisco.200 € per passenger.Departing Fri, 11 Sep, returning Mon, 14 Sep.Return flight with Allegiant Air and Frontier Airlines.Outbound indirect flight with Allegiant Air, departs from Des Moines on Fri, 11 Sep, arriving in San Francisco International.Inbound indirect flight with Frontier Airlines, departs from San Francisco International on Mon, 14 Sep, arriving in Des Moines.Price includes taxes and charges.From 200 €, select.
San Francisco.231 € per passenger.Departing Thu, 29 Oct, returning Mon, 2 Nov.Return flight with Allegiant Air and Frontier Airlines.Outbound indirect flight with Allegiant Air, departs from Des Moines on Thu, 29 Oct, arriving in San Francisco International.Inbound indirect flight with Frontier Airlines, departs from San Francisco International on Mon, 2 Nov, arriving in Des Moines.Price includes taxes and charges.From 231 €, select.
San Francisco.245 € per passenger.Departing Mon, 28 Sep, returning Thu, 1 Oct.Return flight with Allegiant Air and Frontier Airlines.Outbound indirect flight with Allegiant Air, departs from Des Moines on Mon, 28 Sep, arriving in San Francisco International.Inbound indirect flight with Frontier Airlines, departs from San Francisco International on Thu, 1 Oct, arriving in Des Moines.Price includes taxes and charges.From 245 €, select.
San Francisco.248 € per passenger.Departing Fri, 9 Oct, returning Mon, 12 Oct.Return flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Des Moines on Fri, 9 Oct, arriving in San Francisco International.Inbound indirect flight with Frontier Airlines, departs from San Francisco International on Mon, 12 Oct, arriving in Des Moines.Price includes taxes and charges.From 248 €, select.
San Francisco.262 € per passenger.Departing Sat, 29 Aug, returning Sat, 5 Sep.Return flight with Delta.Outbound indirect flight with Delta, departs from Des Moines on Sat, 29 Aug, arriving in San Francisco International.Inbound indirect flight with Delta, departs from San Francisco International on Sat, 5 Sep, arriving in Des Moines.Price includes taxes and charges.From 262 €, select.
San Francisco.270 € per passenger.Departing Mon, 16 Nov, returning Fri, 20 Nov.Return flight with Allegiant Air and Frontier Airlines.Outbound indirect flight with Allegiant Air, departs from Des Moines on Mon, 16 Nov, arriving in San Francisco International.Inbound indirect flight with Frontier Airlines, departs from San Francisco International on Fri, 20 Nov, arriving in Des Moines.Price includes taxes and charges.From 270 €, select.
San Francisco.398 € per passenger.Departing Mon, 27 Jul, returning Mon, 17 Aug.Return flight with Allegiant Air and Frontier Airlines.Outbound indirect flight with Allegiant Air, departs from Des Moines on Mon, 27 Jul, arriving in San Francisco International.Inbound indirect flight with Frontier Airlines, departs from San Francisco International on Mon, 17 Aug, arriving in Des Moines.Price includes taxes and charges.From 398 €, select.
San Francisco.407 € per passenger.Departing Sun, 6 Dec, returning Fri, 11 Dec.Return flight with Allegiant Air and Frontier Airlines.Outbound indirect flight with Allegiant Air, departs from Des Moines on Sun, 6 Dec, arriving in San Francisco International.Inbound indirect flight with Frontier Airlines, departs from San Francisco International on Fri, 11 Dec, arriving in Des Moines.Price includes taxes and charges.From 407 €, select.
San Francisco.409 € per passenger.Departing Wed, 6 Jan, returning Wed, 20 Jan.Return flight with United.Outbound indirect flight with United, departs from Des Moines on Wed, 6 Jan, arriving in San Francisco International.Inbound indirect flight with United, departs from San Francisco International on Wed, 20 Jan, arriving in Des Moines.Price includes taxes and charges.From 409 €, select.
San Francisco.427 € per passenger.Departing Sat, 19 Dec, returning Tue, 19 Jan.Return flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Des Moines on Sat, 19 Dec, arriving in San Francisco International.Inbound indirect flight with Southwest Airlines, departs from San Francisco International on Tue, 19 Jan, arriving in Des Moines.Price includes taxes and charges.From 427 €, select.
San Francisco.550 € per passenger.Departing Sun, 19 Jul, returning Sun, 26 Jul.Return flight with Allegiant Air and Frontier Airlines.Outbound indirect flight with Allegiant Air, departs from Des Moines on Sun, 19 Jul, arriving in San Francisco International.Inbound indirect flight with Frontier Airlines, departs from San Francisco International on Sun, 26 Jul, arriving in Des Moines.Price includes taxes and charges.From 550 €, select.

Find the cheapest month to fly from Des Moines to San Francisco International

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Des Moines to San Francisco International flights are currently cheapest in August.
Jul
from 550 €
Aug
from 174 €
Sep
from 200 €
Oct
from 248 €
Nov
from 270 €
Dec
from 407 €
Jan
from 409 €
Feb
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Mar
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Apr
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May
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Jun
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Des Moines to San Francisco International: Alternative routes

Compare routes from Des Moines to San Francisco below. You may find an airport to fly into that's cheaper, faster, or easier than San Francisco International.

San Francisco International

18km from central San Francisco
ClosestCheapest
from 174 €
Search flights

Oakland Metropolitan Oak

19km from central San Francisco
from 260 €
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Concord

40km from central San Francisco
Search flights

San Jose International

63km from central San Francisco
from 234 €
Search flights

San Jose Reid-Hillview

72km from central San Francisco
Search flights

Santa Rosa

88km from central San Francisco
from 350 €
Search flights

Des Moines to San Francisco: Flight information

The things to know before you go.
Cheapest flight found174 €
Cheapest month to flyAugust

Finding cheap flights from Des Moines to San Francisco International: Frequently asked questions

The best price we found for a return flight from Des Moines to San Francisco International is 174 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Des Moines to San Francisco International. But we found flights with one or more stops from 174 €.
As of July 2026, there are no flights flying from Des Moines to San Francisco International.
The cheapest month to fly from Des Moines to San Francisco International is usually August.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Des Moines Airport to San Francisco International Airport on Monday, 17 August 2026.
No airlines currently offer direct flights between Des Moines Airport and San Francisco International Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to San Francisco International but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to San Francisco is around 40 days in advance, so don’t leave your flight to the last minute.

Currently, Allegiant Air offers the cheapest flight tickets to San Francisco International.

Flying from Des Moines Airport (DSM) to San Francisco International Airport (SFO): what you need to know

  • San Francisco's timezone is UTC-8, which makes San Francisco two hours behind Des Moines.

  • Give yourself plenty of time to catch your DSM to SFO flight. As a rule of thumb, arrive two hours before international departures and an hour ahead for domestic flights.

  • During popular months like August, you'll want to get to the airport even earlier. Plan to arrive two hours before a domestic departure and four hours ahead of international flights whenever you're travelling during peak periods in general.

  • We make it a piece of cake to book a flight with a stopover. To see all your options for tickets from Des Moines Airport to San Francisco International Airport, uncheck 'Direct flights only.' Then, pick a flight offering a stop long enough to explore the city of your choice. Top stopovers between DSM and SFO include:

    • Denver International Airport

    • Phoenix Sky Harbour Airport

    • Harry Reid International Airport

How to find the cheapest flights from Des Moines Airport (DSM) to San Francisco International Airport (SFO)

  • The cheapest price we've found for a one-way Des Moines Airport to San Francisco International Airport flight is 76 €. A round-trip ticket is currently 174 €. Depending on the availability and when you book, these fares can change.

  • To find cheap tickets from DSM to SFO, book ahead. Airlines tend to offer lower prices when flights are first released.

  • If you're flexible with your trip dates, try using the 'Whole month' search function. It'll find the cheapest price across each month when searching for a flight from Des Moines Airport to San Francisco International Airport.

  • Landing cheap flights from DSM to SFO couldn't be easier with Price Alerts. Simply set up one of these automatic alerts and we'll get in touch when a new deal comes up.

  • Tailor your flights using filters. Choose your ideal arrival and departure times, total journey duration and airlines. You can also sort the results by 'Fastest,' 'Best' or 'Cheapest' flights from Des Moines Airport to San Francisco International Airport.

Handy information about Des Moines Airport (DSM)

  • You'll find DSM at 5800 Fleur Drive, Suite 201.

  • Of the flights that depart from Des Moines Airport, 77% land on schedule at their destination.

  • To get to Des Moines Airport from central Des Moines, it takes around 15 minutes by car. This depends on traffic though. It's approximately 11 kilometres from the airport to the city centre.

  • You can expect a journey time of about 30 minutes when using public transport.

  • Need a handy hotel close to DSM? If you're boarding an early flight from Des Moines Airport to San Francisco International Airport, these accommodation options will have you sleeping moments from your departure gate:

Arriving at San Francisco International Airport (SFO)

When to fly to San Francisco International Airport (SFO)

  • It's time to work out your trip dates for your flight from Des Moines Airport to San Francisco International Airport. July is the busiest month to visit San Francisco. If you like a more relaxed vibe, go in March.

  • Lock in your flight from Des Moines Airport to San Francisco International Airport for September if you'd like to visit San Francisco during its warmest month. You can expect temperatures of between 12ºC (54ºF) and 24ºC (75ºF).

  • If you want cooler conditions, look for a cheap ticket from DSM to SFO in January. Temperatures average between 5ºC (41ºF) and 16ºC (61ºF) then.

Explore more of the United States

  • San Francisco has its own special appeal, but there are so many other parts of the United States waiting to be discovered. About 64 kilometres south-east of San Francisco, a trip to San Jose will keep you on the go. Start with popular sights like Winchester Mystery House, The Tech Interactive and Santa Clara Valley.

  • If you're ready to explore another well-known destination in the United States, head for Fresno, about 257 kilometres south-east of San Francisco. Forestiere Underground Gardens, Shinzen Japanese Garden and Fresno Chaffee Zoo are highlights.

Plan the rest of your trip from Des Moines to San Francisco

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.