51 € Cheap Flights from La Serena to Antofagasta

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Flight deals from La Serena to Antofagasta

Looking for a cheap last-minute deal or the best return flight from La Serena Airport to Antofagasta Airport? If you want to travel next month, return fares start from 51 €. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from La Serena to Antofagasta

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like La Serena to Antofagasta flights are currently cheapest in August.

Direct flights from La Serena to Antofagasta

La Serena to Antofagasta: Alternative routes

Compare routes from La Serena to Antofagasta below. You may find an airport to fly into that's cheaper, faster, or easier than Antofagasta.

La Serena to Antofagasta: Flight information

The things to know before you go.
Cheapest flight found51 €
Cheapest month to flyJuly
Average flight time1 hr, 22 mins
Most popular airlineJetSmart
Average flights per week25

Finding cheap flights from La Serena to Antofagasta: Frequently asked questions

The best price we found for a return flight from La Serena to Antofagasta is 51 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
1 hour and 22 minutes is the average flight time from La Serena to Antofagasta.
JetSmart, LATAM Airlines and LATAM Airlines Peru fly direct from La Serena to Antofagasta.
As of July 2026, there are 25 flights per week flying from La Serena to Antofagasta.
The cheapest month to fly from La Serena to Antofagasta is usually July.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from La Serena Airport to Antofagasta Airport on Friday, 31 July 2026.
Yes – the average flight time is 1 hour and 22 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Antofagasta but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Antofagasta is around 40 days in advance, so don’t leave your flight to the last minute.

Currently, JetSmart offers the cheapest flight tickets to Antofagasta.

Travelling from La Serena Airport (LSC) to Antofagasta Airport (ANF): what you need to know

  • The average time for a direct flight from La Serena Airport to Antofagasta Airport is 1 hour 20 minutes.

  • La Serena and Antofagasta are in the same timezone, UTC-3.

  • Flights from LSC to ANF start from 09:38 — the earliest with JetSMART. The last service of the day is at 21:07 with JetSMART. In total, you can take your pick of 18 weekly La Serena Airport to Antofagasta Airport flights.

  • Give yourself plenty of time to make your LSC to ANF flight. As a general rule, arrive two hours before international departures and an hour ahead for domestic flights.

  • During popular months like June, it's best to get to the airport well in advance. Plan to arrive two hours before a domestic departure and four hours ahead for an international flight when you travel during a peak period in general.

  • With direct flights from La Serena Airport to Antofagasta Airport available through a range of airlines, getting to Antofagasta (and then other parts of Chile) is easy. You can travel nonstop with these carriers:

  • The airline that passengers book most often on this route is JetSmart.

  • LATAM Airlines is the most punctual carrier that operates LSC to ANF flights. A reliable 93.85% of its services on this route arrive as scheduled.

  • If you'd love to explore a different city along the way, look for a flight with a stopover. To see all your options for tickets from La Serena Airport to Antofagasta Airport, uncheck 'Direct flights only.' Santiago Arturo Merino Benitez Airport is a popular stop between LSC and ANF.

How to find the cheapest flights from La Serena Airport (LSC) to Antofagasta Airport (ANF)

  • 23 € is currently the best price for a one-way La Serena Airport to Antofagasta Airport flight. A return flight starts at 51 €. These fares can change depending on demand and availability.

  • To pick up cheap tickets from LSC to ANF, book your journey one month before your departure date.

  • The cheapest month for flights from La Serena Airport to Antofagasta Airport is June. Use the 'Whole month' tool to find the lowest prices if you have flexible travel dates.

  • Never miss a deal on cheap flights from LSC to ANF by creating a Price Alert. You'll get an email or push notification on the app when fares go down.

  • Discover the perfect flight for you by using the filters. To see the 'Best,' 'Cheapest' or 'Fastest' flights from La Serena Airport to Antofagasta Airport, use the 'Sort by' function. You can also filter results by airline, departure and arrival times, and journey duration.

Handy information about La Serena Airport (LSC)

  • La Serena Airport maintains a strong on-time record, so you're less likely to experience disruptions. Departures from LSC land on schedule 85% of the time.

  • To get to La Serena Airport from central La Serena, it'll take about 20 minutes by car. This depends on traffic though. It's approximately 13 kilometres from the airport to the city centre.

  • The journey on public transport usually takes 35 minutes.

  • Need a convenient hotel near LSC? If you're catching an early flight from La Serena Airport to Antofagasta Airport, these accommodation options will put you moments from check-in:

Arriving at Antofagasta Airport (ANF)

  • After your La Serena Airport to Antofagasta Airport flight has landed, relax at a hotel close by. Hermoso Departamento con Laguna Navegable is a good option that's not too far from ANF.

  • Pick up a Antofagasta Airport rental car and discover Antofagasta and beyond with your own wheels. United rent a car, Street Rent a Car and Euro are leading providers to choose from here.

  • Lock in the best deal by booking your ride from Antofagasta Airport about four weeks ahead of your trip.

Getting from Antofagasta Airport (ANF) to central Antofagasta

  • Antofagasta Airport is roughly 16 kilometres from the centre of Antofagasta. The drive time takes around 20 minutes.

  • Travelling by public transport will take you roughly 35 minutes.

When to fly to Antofagasta Airport (ANF)

  • The quietest month for a flight from La Serena Airport to Antofagasta Airport is March, while June is the busiest. Choose the ideal time to visit Antofagasta based on whether you prefer a more relaxed vibe or a faster pace.

  • The warmest month in Antofagasta is February, with temperatures ranging between 16ºC (61ºF) and 25ºC (77ºF). Book your flights from La Serena Airport to Antofagasta Airport in this month if this is the kind of weather you like.

  • Look for cheap tickets from LSC to ANF in July if you like travelling in cooler conditions. Temperatures are at their lowest then, ranging between 10ºC (50ºF) and 20ºC (68ºF) on average.

Explore more of Chile

  • You've done Antofagasta, now it's time to explore other corners of Chile. Travel about 386 kilometres north to Iquique to tick off its popular sights. From Playa Cavancha to Playa Brava and Dunas de Iquique, you'll have a full itinerary ahead.

  • Around 193 kilometres north-east of Antofagasta, Calama is another favourite stop in Chile. Experience the best of this destination with a visit to Mina de Chuquicamata, Catedral de San Juan Bautista and Parque para la Preservacion de la Memoria Historica.

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.