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400 € Cheap Flights from Panama City Tocumen International to Cuzco

Compare Panama City Tocumen International to Cuzco flight deals

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Flight deals from Panama City Tocumen International to Cuzco

Looking for a cheap last-minute deal or the best return flight from Panama City Tocumen International Airport to Cuzco Airport? If you want to travel next month, return fares start from 467 €. Find the lowest prices on one-way and return tickets right here.
Cuzco.400 € per passenger.Departing Fri, 30 Oct, returning Sat, 7 Nov.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Fri, 30 Oct, arriving in Cuzco.Inbound indirect flight with Avianca, departs from Cuzco on Sat, 7 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From 400 €, select.
Cuzco.405 € per passenger.Departing Tue, 4 May, returning Wed, 19 May.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 4 May, arriving in Cuzco.Inbound indirect flight with Avianca, departs from Cuzco on Wed, 19 May, arriving in Panama City Tocumen International.Price includes taxes and charges.From 405 €, select.
Cuzco.407 € per passenger.Departing Tue, 8 Dec, returning Tue, 15 Dec.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 8 Dec, arriving in Cuzco.Inbound indirect flight with Avianca, departs from Cuzco on Tue, 15 Dec, arriving in Panama City Tocumen International.Price includes taxes and charges.From 407 €, select.
Cuzco.407 € per passenger.Departing Sat, 12 Sep, returning Sun, 20 Sep.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Sat, 12 Sep, arriving in Cuzco.Inbound indirect flight with Avianca, departs from Cuzco on Sun, 20 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From 407 €, select.
Cuzco.407 € per passenger.Departing Mon, 22 Feb, returning Fri, 26 Feb.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 22 Feb, arriving in Cuzco.Inbound indirect flight with Avianca, departs from Cuzco on Fri, 26 Feb, arriving in Panama City Tocumen International.Price includes taxes and charges.From 407 €, select.
Cuzco.407 € per passenger.Departing Tue, 3 Nov, returning Sun, 8 Nov.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 3 Nov, arriving in Cuzco.Inbound indirect flight with Avianca, departs from Cuzco on Sun, 8 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From 407 €, select.
Cuzco.409 € per passenger.Departing Sat, 10 Oct, returning Wed, 14 Oct.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Sat, 10 Oct, arriving in Cuzco.Inbound indirect flight with Avianca, departs from Cuzco on Wed, 14 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From 409 €, select.
Cuzco.467 € per passenger.Departing Wed, 12 Aug, returning Sun, 16 Aug.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Wed, 12 Aug, arriving in Cuzco.Inbound indirect flight with Avianca, departs from Cuzco on Sun, 16 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From 467 €, select.
Cuzco.471 € per passenger.Departing Mon, 28 Sep, returning Sat, 3 Oct.Return flight with Avianca and JetSmart.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 28 Sep, arriving in Cuzco.Inbound indirect flight with JetSmart, departs from Cuzco on Sat, 3 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From 471 €, select.
Cuzco.516 € per passenger.Departing Thu, 20 Aug, returning Sat, 19 Sep.Return flight with Avianca and JetSmart.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Thu, 20 Aug, arriving in Cuzco.Inbound indirect flight with JetSmart, departs from Cuzco on Sat, 19 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From 516 €, select.
Cuzco.535 € per passenger.Departing Fri, 25 Dec, returning Tue, 5 Jan.Return flight with Avianca and JetSmart.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Fri, 25 Dec, arriving in Cuzco.Inbound indirect flight with JetSmart, departs from Cuzco on Tue, 5 Jan, arriving in Panama City Tocumen International.Price includes taxes and charges.From 535 €, select.
Cuzco.537 € per passenger.Departing Thu, 11 Mar, returning Fri, 19 Mar.Return flight with Avianca.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Thu, 11 Mar, arriving in Cuzco.Inbound indirect flight with Avianca, departs from Cuzco on Fri, 19 Mar, arriving in Panama City Tocumen International.Price includes taxes and charges.From 537 €, select.

Find the cheapest month to fly from Panama City Tocumen International to Cuzco

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City Tocumen International to Cuzco flights are currently cheapest in May.
Jul
Find prices
Aug
from 467 €
Sep
from 407 €
Oct
from 409 €
Nov
from 407 €
Dec
from 407 €
Jan
Find prices
Feb
from 407 €
Mar
from 537 €
Apr
Find prices
May
from 405 €
Jun
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Panama City Tocumen International to Cuzco: Alternative routes

Compare routes from Panama City Tocumen International to Cuzco below. You may find an airport to fly into that's cheaper, faster, or easier than Cuzco.

Cuzco

1km from central Cuzco
ClosestCheapest
from 400 €
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Panama City to Cuzco: Flight information

The things to know before you go.
Cheapest flight found400 €
Cheapest month to flyOctober

Finding cheap flights from Panama City Tocumen International to Cuzco: Frequently asked questions

The best price we found for a return flight from Panama City Tocumen International to Cuzco is 400 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Panama City Tocumen International to Cuzco. But we found flights with one or more stops from 400 €.
As of July 2026, there are no flights flying from Panama City Tocumen International to Cuzco.
The cheapest month to fly from Panama City Tocumen International to Cuzco is usually October.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Panama City Tocumen International Airport to Cuzco Airport on Friday, 30 October 2026.
No airlines currently offer direct flights between Panama City Tocumen International Airport and Cuzco Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Cuzco but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Cuzco is around 40 days in advance, so don’t leave your flight to the last minute.

Currently, Avianca offers the cheapest flight tickets to Cuzco.

Travelling from Panama City Tocumen International Airport (PTY) to Cuzco Airport (CUZ): what you need to know

  • Panama City and Cuzco are both in the UTC-5 timezone. That means there's no time difference to consider.

  • For a stress-free journey, turn up at the airport two hours ahead of international flights and one hour before domestic departures. This way, you can comfortably board your PTY to CUZ flight.

  • During popular months like July, you'll want to get to the airport earlier than normal. Plan to arrive two hours before domestic departures and four hours ahead of an international flight whenever you're travelling during peak periods in general.

  • Pick a stopover if you prefer to break up your flight. Just deselect 'Direct flights only' to see your options for tickets from Panama City Tocumen International Airport to Cuzco Airport. Bogota Airport is a popular stopover on the PTY to CUZ route.

How to find the cheapest flights from Panama City Tocumen International Airport (PTY) to Cuzco Airport (CUZ)

  • The lowest price we've found for a one-way Panama City Tocumen International Airport to Cuzco Airport flight is 225 €. A round-trip ticket is currently 400 €. Depending on the availability when you book, these fares can change.

  • To pick up cheap tickets from PTY to CUZ, book ahead. Airlines generally offer their best fares when flights are first released.

  • The 'Whole month' tool shows you the cheapest flights from Panama City Tocumen International Airport to Cuzco Airport throughout the month. It's a great way to find a bargain if your trip dates are flexible.

  • Landing cheap flights from PTY to CUZ couldn't be easier with Price Alerts. Simply create one of these automatic alerts and we'll notify you when a new deal comes up.

  • Choose your preferred arrival and departure times, airlines and number of stops with the filters. Or sort your results by 'Cheapest' to see the best deals on flights from Panama City Tocumen International Airport to Cuzco Airport.

Handy information about Panama City Tocumen International Airport (PTY)

  • Panama City Tocumen International Airport has a strong on-time record, reducing your chances of a delayed flight. Departures from PTY land at their destination as scheduled 88% of the time.

  • Panama City Tocumen International Airport is around 24 kilometres from central Panama City. If you're driving, ride-sharing or catching a taxi from the centre, it'll take 35 minutes or so to get there, depending on the traffic.

  • The journey on public transport usually takes 50 minutes.

  • Searching for a handy hotel close to PTY? If you're boarding an early flight from Panama City Tocumen International Airport to Cuzco Airport, these accommodation options will put you moments from your check-in counter:

Arriving at Cuzco Airport (CUZ)

  • Reserve a hotel near CUZ if you're on a late Panama City Tocumen International Airport to Cuzco Airport flight. Settle into one of these accommodation options and avoid the hassle of a long transfer:

  • Pick up a Cuzco Airport rental car and explore Cuzco and beyond with your own set of wheels. Sixt, FlexWays and Europcar are leading providers to choose from here.

  • Booking your ride from Cuzco Airport about four weeks ahead boosts your odds of scoring a great price.

When to fly to Cuzco Airport (CUZ)

  • It's time to work out your trip dates for your flight from Panama City Tocumen International Airport to Cuzco Airport. September is the busiest month to head to Cuzco. If you prefer a quieter vibe, go in March.

  • The warmest month in Cuzco is November, with temperatures ranging between 6ºC (43ºF) and 18ºC (64ºF). Lock in your flights from Panama City Tocumen International Airport to Cuzco Airport in this month if this is the type of weather you like.

  • If you like travelling in cooler conditions, search for a cheap ticket from PTY to CUZ in July. Average temperatures are between 2ºC (36ºF) and 17ºC (63ºF) then.

Explore more of Peru

  • Arequipa is just one of the many places in Peru waiting to be explored after you've seen Cuzco. Around 322 kilometres away to the south, its top attractions include Historic Centre of Arequipa, Plaza de Armas and Malecón Bolognesi.

  • Huancayo is another well-known destination in Peru and is around 386 kilometres north-west of Cuzco. No trip is complete without dropping by Cristo Rey, Los Pinos - Cochas Chico. Ecological Park and Mirador Chonta.

Plan the rest of your trip from Panama City to Cuzco

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.