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921 € Cheap Flights from Panama City to Istanbul

Compare Panama City to Istanbul flight deals

Find the cheapest month or even day of the year to fly to Istanbul

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Flight deals from Panama City to Istanbul

Looking for a cheap last-minute deal or the best return flight from Panama City to Istanbul? If you want to travel next month, return fares start from 1.009 €. Find the lowest prices on one-way and return tickets right here.
Istanbul.921 € per passenger.Departing Wed, 17 Feb, returning Sat, 27 Feb.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Wed, 17 Feb, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Sat, 27 Feb, arriving in Panama City Tocumen International.Price includes taxes and charges.From 921 €, select.
Istanbul.925 € per passenger.Departing Mon, 22 Feb, returning Thu, 4 Mar.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Mon, 22 Feb, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Thu, 4 Mar, arriving in Panama City Tocumen International.Price includes taxes and charges.From 925 €, select.
Istanbul.925 € per passenger.Departing Sun, 9 May, returning Sun, 30 May.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Sun, 9 May, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Sun, 30 May, arriving in Panama City Tocumen International.Price includes taxes and charges.From 925 €, select.
Istanbul.928 € per passenger.Departing Thu, 10 Sep, returning Fri, 18 Sep.Return flight with Avianca and Transavia France.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Thu, 10 Sep, arriving in Istanbul.Inbound indirect flight with Transavia France, departs from Istanbul on Fri, 18 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From 928 €, select.
Istanbul.944 € per passenger.Departing Wed, 21 Oct, returning Mon, 26 Oct.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Wed, 21 Oct, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Mon, 26 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From 944 €, select.
Istanbul.945 € per passenger.Departing Sun, 20 Sep, returning Mon, 5 Oct.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Sun, 20 Sep, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Mon, 5 Oct, arriving in Panama City Tocumen International.Price includes taxes and charges.From 945 €, select.
Istanbul.946 € per passenger.Departing Sat, 10 Apr, returning Tue, 20 Apr.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Sat, 10 Apr, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Tue, 20 Apr, arriving in Panama City Tocumen International.Price includes taxes and charges.From 946 €, select.
Istanbul.947 € per passenger.Departing Fri, 16 Apr, returning Sat, 1 May.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Fri, 16 Apr, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Sat, 1 May, arriving in Panama City Tocumen International.Price includes taxes and charges.From 947 €, select.
Istanbul.950 € per passenger.Departing Thu, 4 Mar, returning Sat, 13 Mar.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Thu, 4 Mar, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Sat, 13 Mar, arriving in Panama City Tocumen International.Price includes taxes and charges.From 950 €, select.
Istanbul.956 € per passenger.Departing Mon, 10 Aug, returning Fri, 4 Sep.Return flight with Avianca and Pegasus Airlines.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Mon, 10 Aug, arriving in Istanbul Sabiha.Inbound indirect flight with Pegasus Airlines, departs from Istanbul Sabiha on Fri, 4 Sep, arriving in Panama City Tocumen International.Price includes taxes and charges.From 956 €, select.
Istanbul.977 € per passenger.Departing Tue, 15 Sep, returning Fri, 13 Nov.Return flight with Avianca and Transavia France.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 15 Sep, arriving in Istanbul Sabiha.Inbound indirect flight with Transavia France, departs from Istanbul on Fri, 13 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From 977 €, select.
Istanbul.984 € per passenger.Departing Sat, 25 Jul, returning Wed, 19 Aug.Return flight with KLM.Outbound indirect flight with KLM, departs from Panama City Tocumen International on Sat, 25 Jul, arriving in Istanbul.Inbound indirect flight with KLM, departs from Istanbul on Wed, 19 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From 984 €, select.
Istanbul.1.003 € per passenger.Departing Tue, 13 Oct, returning Fri, 13 Nov.Return flight with Avianca and Wizz Air UK.Outbound indirect flight with Avianca, departs from Panama City Tocumen International on Tue, 13 Oct, arriving in Istanbul.Inbound indirect flight with Wizz Air UK, departs from Istanbul on Fri, 13 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From 1.003 €, select.
Istanbul.1.008 € per passenger.Departing Wed, 11 Nov, returning Sat, 21 Nov.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Wed, 11 Nov, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Sat, 21 Nov, arriving in Panama City Tocumen International.Price includes taxes and charges.From 1.008 €, select.
Istanbul.1.009 € per passenger.Departing Wed, 5 Aug, returning Sat, 22 Aug.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Wed, 5 Aug, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Sat, 22 Aug, arriving in Panama City Tocumen International.Price includes taxes and charges.From 1.009 €, select.
Istanbul.1.013 € per passenger.Departing Sat, 30 Jan, returning Mon, 22 Feb.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Panama City Tocumen International on Sat, 30 Jan, arriving in Istanbul.Inbound indirect flight with Air Europa, departs from Istanbul on Mon, 22 Feb, arriving in Panama City Tocumen International.Price includes taxes and charges.From 1.013 €, select.

Find the cheapest month to fly from Panama City to Istanbul

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Istanbul flights are currently cheapest in February.
Jul
from 1.340 €
Aug
from 1.009 €
Sep
from 928 €
Oct
from 944 €
Nov
from 1.008 €
Dec
from 1.248 €
Jan
from 1.046 €
Feb
from 921 €
Mar
from 950 €
Apr
from 946 €
May
from 925 €
Jun
from 1.147 €

Direct flights from Panama City to Istanbul

Alternative Panama City to Istanbul routes

Looking for the cheapest, fastest or easiest route from Panama City to Istanbul? You could fly into the following airports instead.

Istanbul Sabiha

30km from central Istanbul
Closest
from 956 €
Search flights

Istanbul

34km from central Istanbul
Cheapest
from 921 €
Search flights

Panama City to Istanbul: Flight information

The things to know before you go.
Cheapest flight found921 €
Cheapest month to flyFebruary
Average flight time12 hrs, 50 mins
Most popular airlineTurkish Airlines
Average flights per week25

Finding cheap flights from Panama City to Istanbul: Frequently asked questions

There are 2 airports in Istanbul: Istanbul Sabiha and Istanbul.
The best price we found for a return flight from Panama City to Istanbul is 921 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
12 hours and 50 minutes is the average flight time from Panama City to Istanbul.
Turkish Airlines and Copa fly direct from Panama City to Istanbul.
As of July 2026, there are 25 flights per week flying from Panama City to Istanbul.
The cheapest month to fly from Panama City to Istanbul is usually February.
If you're flying from Panama City, the cheapest airport near Istanbul is Istanbul – which is 34.4 km away from the centre of Istanbul. We've found flights into this airport from 921 €.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Istanbul on Wednesday, 17 February 2027.
Yes – the average flight time is 12 hours and 50 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Istanbul but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Istanbul is around 40 days in advance, so don’t leave your flight to the last minute.

In July, the average temperature is usually around 24°C. August is typically the warmest month in Istanbul, when it usually averages around 27°C. You can expect the least rain in August. The coldest month is January, with temperatures averaging 4°C. The rainiest month is December.
The cheapest airline that flies to Istanbul is Air Europa. And the cheapest airline that flies to Istanbul Airport is Turkish Airlines.

Travelling from Panama City to Istanbul: what you need to know

  • Panama City has two main airports where you can start your adventure. Check out your options for reserving a flight from Panama City to Istanbul departing from Panama City Tocumen International Airport (PTY) or Balboa Airport (BLB).

  • Istanbul Airport (IST) and Istanbul Sabiha Airport (SAW) are Istanbul's major entry points.

  • The average length of a direct Panama City to Istanbul flight is 12 hours 50 minutes.

  • Istanbul's timezone is UTC+3, making Istanbul eight hours ahead of Panama City.

  • With ten flights a week between the two airports, Panama City Tocumen International Airport (PTY) to Istanbul Airport (IST) is the busiest route. Board the first flight from Panama City to Istanbul with Turkish Airlines at 18:55. If you prefer to make the most of your day before taking off, the last departure from PTY to IST is with Turkish Airlines at 21:55.

  • To ensure you don't miss your Panama City to Istanbul flight, leave enough time for things like baggage drop and finding your gate. Arriving two hours before international departures and one hour before domestic flights is the general rule to follow.

  • You can expect longer queues during popular months such as July. Arriving up to four hours ahead of an international flight and two hours for domestic departures will help ensure a smooth travel experience.

How to find the cheapest flights from Panama City to Istanbul

  • To snag cheap Panama City to Istanbul flights, reserve your journey two months before your departure.

  • The best month for scoring cheap plane tickets from Panama City to Istanbul is July. Use the 'Whole month' tool to compare flight prices, then choose the dates offering the lowest fares.

  • Save time searching for cheap flights from Panama City to Istanbul by creating a Price Alert. You'll get an email or notification on the app when a special offer becomes available.

  • Find an affordable Panama City to Istanbul flight with the help of our filters. Choose your preferred times, airlines and number of stops, then sort the results by 'Cheapest' to see the best deals.

Flying from Panama City

Panama City Tocumen International Airport (PTY)

  • Set out from Panama City Tocumen International Airport (PTY) on a nonstop flight from Panama City to Istanbul. From PTY, you can travel directly to Istanbul Airport (IST).

  • Turkish Airlines is a well-known airline that offers direct Panama City to Istanbul plane tickets from PTY.

  • Think about adding a stopover to potentially save on your Panama City to Istanbul flight. Simply uncheck 'Direct flights only' when searching for departures from Panama City Tocumen International Airport. Break up your trip (and maybe save some cash) by stopping at one of these popular options:

    • Atlanta Hartsfield-Jackson Airport (ATL)

    • Amsterdam Schiphol Airport (AMS)

    • Madrid Airport (MAD)

  • PTY is about 18 kilometres from central Panama City. If you're ride-sharing, catching a taxi or driving from the centre, it'll take you 35 minutes or so to get there, depending on the traffic. If you're using public transport, expect the journey time to be around 50 minutes.

  • Booked an early flight from Panama City to Istanbul? Avoid the stress of rushing to the terminal (and sneak in some extra precious sleep) by choosing one of these hotels near Panama City Tocumen International Airport:

  • Panama City Tocumen International Airport maintains a strong on-time performance, so you're less likely to experience disruptions. Departures from PTY touch down on schedule 88% of the time.

Balboa Airport (BLB)

  • With public transport, you can travel from central Panama City to BLB in around 20 minutes. The airport is roughly 5 kilometres away. Driving will take you about 10 minutes.

  • You're going on holiday, so why not book an extra night away from home? Consider checking in to one of these hotels near Balboa Airport the day before your flight from Panama City to Istanbul:

  • The majority of flights that leave Balboa Airport reach their destination within the expected time frame. It maintains a high on-time performance rate of 88%.

Arriving in Istanbul

Istanbul Airport (IST)

  • Istanbul Airport (IST) is approximately 32 kilometres from the centre of Istanbul. If you're catching a taxi or a ride-share, the drive will take around 45 minutes.

  • If you're travelling on public transport, expect a journey time of about 1 hour 10 minutes.

  • The last thing you need is a lengthy journey to your hotel if you're getting in late on a flight from Panama City to Istanbul. Reserve one of these accommodation options near IST instead:

  • Hit the road running by picking up a Istanbul Airport rental car. Grab your wheels from Hit, Avec car rentals or Eren Rent a Car to explore Istanbul and beyond.

  • Booking your ride from Istanbul Airport about two weeks ahead can help you secure the lowest rate.

Istanbul Sabiha Airport (SAW)

  • Central Istanbul is approximately 31 kilometres from Istanbul Sabiha Airport (SAW). As soon as your flight from Panama City to Istanbul has landed and you've made your way to arrivals, the drive should be around 1 hour 5 minutes.

  • You can expect the trip to take about 1 hour 40 minutes on public transport.

  • After your flight from Panama City to Istanbul, tuck yourself in at a hotel close to SAW. These are some great accommodation options that'll help you sink into relaxation mode:

  • The quickest way to reach your destination is with a Istanbul Sabiha Airport rental car. Pick up your wheels from Essence, Eren Rent a Car or 724 Rent and set off in the blink of an eye.

  • Avoid paying more than you need to. Booking your ride four weeks ahead of your arrival at SAW will save you money.

Best time to go to Istanbul

  • It's time to pick your trip dates for your flight from Panama City to Istanbul. August is the busiest month to visit Istanbul. If you prefer a more low-key vibe, go in March.

  • Lock in a Panama City to Istanbul ticket departing in July if you want to visit the city during its warmest month. Expect temperatures in Istanbul to range from 21ºC (70ºF) to 30ºC (86ºF).

  • If you like cooler conditions, search for a cheap flight from Panama City to Istanbul in January when temperatures average between 2ºC (36ºF) and 11ºC (52ºF).

More about Istanbul

  • After booking your flight from Panama City to Istanbul, take your pick from prime hotels that put you close to the action. Make one of these options your base for exploring Istanbul:

  • There are so many things to explore in this city it can be hard to figure out where to begin. Hagia Sophia, Historic Areas of Istanbul and Hagia Sophia History and Experience Museum are popular attractions which should feature on any good Istanbul itinerary.

Explore more of Türkiye (Turkey)

  • Ankara is just one of the many cities in Türkiye (Turkey) waiting to be discovered once you've taken in the sights of Istanbul. Around 354 kilometres to the east, check out popular attractions including The Roman Theatre, Kocatepe Mosque and Museum of Anatolian Civilizations.

  • Izmir is another essential stop in Türkiye (Turkey) and is around 322 kilometres southwest of Istanbul. No journey is complete without visiting Aegean Coast, Smyrna Basilika and Ataturk Konak Square.

Plan the rest of your trip from Panama City to Istanbul

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.