594 € Cheap Flights from Knoxville to Madrid

Compare Knoxville to Madrid flight deals

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Flight deals from Knoxville to Madrid

Looking for a cheap last-minute deal or the best return flight from Knoxville Airport to Madrid Airport? If you want to travel next month, return fares start from 719 €. Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from Knoxville to Madrid

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Knoxville to Madrid flights are currently cheapest in October.

Knoxville to Madrid: Alternative routes

Compare routes from Knoxville to Madrid below. You may find an airport to fly into that's cheaper, faster, or easier than Madrid.

Knoxville to Madrid: Flight information

The things to know before you go.
Cheapest flight found594 €
Cheapest month to flySeptember

Finding cheap flights from Knoxville to Madrid: Frequently asked questions

The best price we found for a return flight from Knoxville to Madrid is 594 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Knoxville to Madrid. But we found flights with one or more stops from 594 €.
As of July 2026, there are no flights flying from Knoxville to Madrid.
The cheapest month to fly from Knoxville to Madrid is usually September.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Knoxville Airport to Madrid Airport on Wednesday, 30 September 2026.
No airlines currently offer direct flights between Knoxville Airport and Madrid Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Madrid but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Madrid is around 40 days in advance, so don’t leave your flight to the last minute.

Currently, Allegiant Air offers the cheapest flight tickets to Madrid.

Flying from Knoxville Airport (TYS) to Madrid Airport (MAD): what you need to know

  • The timezone in Madrid is UTC+1, which is six hours ahead of Knoxville.

  • For a smooth journey, turn up at the airport two hours ahead of international flights and an hour before domestic departures. This will give you enough time to board your TYS to MAD flight.

  • During popular months such as October, it's best to get to the airport even earlier. Plan to arrive two hours before a domestic departure and four hours ahead of an international flight when you travel during a peak period in general.

How to find the cheapest flights from Knoxville Airport (TYS) to Madrid Airport (MAD)

  • 222 € is the lowest price for a one-way Knoxville Airport to Madrid Airport flight. A return flight starts at 594 €. These prices can change based on demand.

  • It's often best to book as early as possible if you want to find cheap tickets from TYS to MAD. That's because airlines adjust prices based on demand, which tends to increase closer to the date of departure.

  • Finding cheap flights from Knoxville Airport to Madrid Airport is more likely if you're flexible with your dates. Use the 'Whole month' function to see the best prices across every month and snap up a great deal.

  • You won't have to check every day to see if fares have gone down when you set up a Price Alert. We'll send you an update as soon as there's a new deal on cheap flights from TYS to MAD.

  • Tailor your trip with filters. Pick your ideal departure and arrival times, total journey duration and airlines. You can also sort results by 'Cheapest,' 'Fastest' or 'Best' flights from Knoxville Airport to Madrid Airport.

Handy information about Knoxville Airport (TYS)

  • You'll find TYS at 2055 Alcoa Highway.

  • Of all flights leaving Knoxville Airport, 76% touch down on time at their destination.

  • Knoxville Airport is around 24 kilometres from central Knoxville. If you're ride-sharing, catching a taxi or driving from the centre, it'll take you 25 minutes or so to get there, depending on the traffic.

  • You can expect a trip time of roughly 50 minutes when using public transport.

  • Get your break off to a hassle-free start by staying near TYS. Whether you've booked an early flight from Knoxville Airport to Madrid Airport or want to avoid feeling rushed, these hotels have you covered:

Arriving at Madrid Airport (MAD)

  • Reserve a hotel near MAD if you're catching a late Knoxville Airport to Madrid Airport flight. Pick one of these accommodation options and skip the long transfer after landing:

  • Begin your adventure by picking up a Madrid Airport rental car. Grab a set of wheels from Record Go, Goldcar or Click and Rent to explore Madrid and beyond.

  • Lock in the best possible rate by booking your ride from Madrid Airport around one week ahead of your trip.

When to fly to Madrid Airport (MAD)

  • It's time to plan your trip dates for your flight from Knoxville Airport to Madrid Airport. July is the busiest month to head to Madrid. If you'd like a quieter vibe, go in March.

  • Book your flight from Knoxville Airport to Madrid Airport for July if you'd like to visit Madrid during its warmest month. Expect temperatures of between 18ºC (64ºF) and 37ºC (99ºF).

  • January has average temperatures of between 0ºC (32ºF) and 12ºC (54ºF). Search for cheap tickets from TYS to MAD sometime around then if you want to travel when it's cooler.

Explore more of Spain

  • Madrid has plenty going for it, but there are so many other corners of Spain waiting to be explored. Around 274 kilometres north-east of Madrid, a visit to Zaragoza will keep your itinerary busy. Start with popular sights like Plaza del Pilar, La Seo del Salvador and Basílica de Nuestra Senora del Pilar.

  • If you're looking to explore another major destination in Spain, consider Salamanca, about 177 kilometres west of Madrid. Catedral de Salamanca, Salamanca, Casco Historico and Plaza Mayor are key reasons to visit.

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.