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163 € Cheap Flights from Detroit Wayne County to Knoxville

Compare Detroit Wayne County to Knoxville flight deals

Find the cheapest month or even day of the year to fly to Knoxville

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Flight deals from Detroit Wayne County to Knoxville

Looking for a cheap last-minute deal or the best return flight from Detroit Wayne County Airport to Knoxville Airport? If you want to travel next month, return fares start from 201 €. Find the lowest prices on one-way and return tickets right here.
Knoxville.163 € per passenger.Departing Tue, 29 Sep, returning Wed, 30 Sep.Return flight with United.Outbound indirect flight with United, departs from Detroit Wayne County on Tue, 29 Sep, arriving in Knoxville.Inbound indirect flight with United, departs from Knoxville on Wed, 30 Sep, arriving in Detroit Wayne County.Price includes taxes and charges.From 163 €, select.
Knoxville.164 € per passenger.Departing Sat, 29 Aug, returning Thu, 3 Sep.Return flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Detroit Wayne County on Sat, 29 Aug, arriving in Knoxville.Inbound indirect flight with Southwest Airlines, departs from Knoxville on Thu, 3 Sep, arriving in Detroit Wayne County.Price includes taxes and charges.From 164 €, select.
Knoxville.201 € per passenger.Departing Sun, 23 Aug, returning Sat, 29 Aug.Return flight with Frontier Airlines and Allegiant Air.Outbound indirect flight with Frontier Airlines, departs from Detroit Wayne County on Sun, 23 Aug, arriving in Knoxville.Inbound indirect flight with Allegiant Air, departs from Knoxville on Sat, 29 Aug, arriving in Detroit Wayne County.Price includes taxes and charges.From 201 €, select.
Knoxville.203 € per passenger.Departing Thu, 22 Oct, returning Mon, 26 Oct.Return flight with United.Outbound indirect flight with United, departs from Detroit Wayne County on Thu, 22 Oct, arriving in Knoxville.Inbound indirect flight with United, departs from Knoxville on Mon, 26 Oct, arriving in Detroit Wayne County.Price includes taxes and charges.From 203 €, select.
Knoxville.210 € per passenger.Departing Fri, 31 Jul, returning Mon, 3 Aug.Return flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Detroit Wayne County on Fri, 31 Jul, arriving in Knoxville.Inbound indirect flight with Frontier Airlines, departs from Knoxville on Mon, 3 Aug, arriving in Detroit Wayne County.Price includes taxes and charges.From 210 €, select.
Knoxville.226 € per passenger.Departing Wed, 14 Oct, returning Wed, 21 Oct.Return flight with Delta.Outbound direct flight with Delta departs from Detroit Wayne County on Wed, 14 Oct, arriving in Knoxville.Inbound direct flight with Delta departs from Knoxville on Wed, 21 Oct, arriving in Detroit Wayne County.Price includes taxes and charges.From 226 €, select.
Knoxville.226 € per passenger.Departing Tue, 8 Sep, returning Sat, 12 Sep.Return flight with Delta.Outbound direct flight with Delta departs from Detroit Wayne County on Tue, 8 Sep, arriving in Knoxville.Inbound direct flight with Delta departs from Knoxville on Sat, 12 Sep, arriving in Detroit Wayne County.Price includes taxes and charges.From 226 €, select.
Knoxville.226 € per passenger.Departing Sat, 16 Jan, returning Sun, 31 Jan.Return flight with Delta.Outbound direct flight with Delta departs from Detroit Wayne County on Sat, 16 Jan, arriving in Knoxville.Inbound direct flight with Delta departs from Knoxville on Sun, 31 Jan, arriving in Detroit Wayne County.Price includes taxes and charges.From 226 €, select.
Knoxville.226 € per passenger.Departing Sun, 23 Aug, returning Sat, 29 Aug.Return flight with Delta.Outbound direct flight with Delta departs from Detroit Wayne County on Sun, 23 Aug, arriving in Knoxville.Inbound direct flight with Delta departs from Knoxville on Sat, 29 Aug, arriving in Detroit Wayne County.Price includes taxes and charges.From 226 €, select.
Knoxville.227 € per passenger.Departing Sat, 29 Aug, returning Thu, 3 Sep.Return flight with Delta.Outbound direct flight with Delta departs from Detroit Wayne County on Sat, 29 Aug, arriving in Knoxville.Inbound direct flight with Delta departs from Knoxville on Thu, 3 Sep, arriving in Detroit Wayne County.Price includes taxes and charges.From 227 €, select.
Knoxville.232 € per passenger.Departing Tue, 29 Sep, returning Sat, 3 Oct.Return flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departs from Detroit Wayne County on Tue, 29 Sep, arriving in Knoxville.Inbound indirect flight with Southwest Airlines, departs from Knoxville on Sat, 3 Oct, arriving in Detroit Wayne County.Price includes taxes and charges.From 232 €, select.
Knoxville.235 € per passenger.Departing Wed, 14 Apr, returning Mon, 19 Apr.Return flight with Delta.Outbound indirect flight with Delta, departs from Detroit Wayne County on Wed, 14 Apr, arriving in Knoxville.Inbound indirect flight with Delta, departs from Knoxville on Mon, 19 Apr, arriving in Detroit Wayne County.Price includes taxes and charges.From 235 €, select.
Knoxville.245 € per passenger.Departing Wed, 22 Jul, returning Fri, 24 Jul.Return flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departs from Detroit Wayne County on Wed, 22 Jul, arriving in Knoxville.Inbound indirect flight with Frontier Airlines, departs from Knoxville on Fri, 24 Jul, arriving in Detroit Wayne County.Price includes taxes and charges.From 245 €, select.
Knoxville.252 € per passenger.Departing Thu, 19 Nov, returning Sun, 22 Nov.Return flight with United.Outbound indirect flight with United, departs from Detroit Wayne County on Thu, 19 Nov, arriving in Knoxville.Inbound indirect flight with United, departs from Knoxville on Sun, 22 Nov, arriving in Detroit Wayne County.Price includes taxes and charges.From 252 €, select.
Knoxville.279 € per passenger.Departing Fri, 31 Jul, returning Sun, 2 Aug.Return flight with Delta.Outbound direct flight with Delta departs from Detroit Wayne County on Fri, 31 Jul, arriving in Knoxville.Inbound direct flight with Delta departs from Knoxville on Sun, 2 Aug, arriving in Detroit Wayne County.Price includes taxes and charges.From 279 €, select.
Knoxville.322 € per passenger.Departing Tue, 29 Sep, returning Sat, 3 Oct.Return flight with Delta.Outbound direct flight with Delta departs from Detroit Wayne County on Tue, 29 Sep, arriving in Knoxville.Inbound direct flight with Delta departs from Knoxville on Sat, 3 Oct, arriving in Detroit Wayne County.Price includes taxes and charges.From 322 €, select.

Find the cheapest month to fly from Detroit Wayne County to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Detroit Wayne County to Knoxville flights are currently cheapest in September.
Jul
from 245 €
Aug
from 201 €
Sep
from 163 €
Oct
from 203 €
Nov
from 252 €
Dec
from 356 €
Jan
from 226 €
Feb
Find prices
Mar
Find prices
Apr
from 235 €
May
Find prices
Jun
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Direct flights from Detroit Wayne County to Knoxville

Detroit Wayne County to Knoxville: Alternative routes

Compare routes from Detroit Wayne County to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Knoxville

18km from central Knoxville
ClosestCheapest
from 163 €
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Detroit to Knoxville: Flight information

The things to know before you go.
Cheapest flight found163 €
Cheapest month to flySeptember
Average flight time1 hr, 41 mins
Most popular airlineWestJet
Average flights per week111

Finding cheap flights from Detroit Wayne County to Knoxville: Frequently asked questions

The best price we found for a return flight from Detroit Wayne County to Knoxville is 163 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
1 hour and 41 minutes is the average flight time from Detroit Wayne County to Knoxville.
WestJet, KLM and Delta fly direct from Detroit Wayne County to Knoxville.
As of July 2026, there are 111 flights per week flying from Detroit Wayne County to Knoxville.
The cheapest month to fly from Detroit Wayne County to Knoxville is usually September.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Detroit Wayne County Airport to Knoxville Airport on Tuesday, 29 September 2026.
Yes – the average flight time is 1 hour and 41 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.

Currently, United and Delta offer the cheapest flight tickets to Knoxville.

Flying from Detroit Wayne County Airport (DTW) to Knoxville Airport (TYS): what you need to know

  • The average length of a direct flight from Detroit Wayne County Airport to Knoxville Airport is 1 hour 40 minutes.

  • Take your pick of 21 weekly Detroit Wayne County Airport to Knoxville Airport flights. The 08:30 departure with Delta Air Lines is the earliest you can take. Delta Air Lines operates the latest service of the day at 20:09.

  • To ensure you get on your DTW to TYS flight, leave enough time to check in and find your gate. Turning up two hours before international departures and an hour before domestic flights is the standard rule.

  • During popular months like July, it's best to get to the airport earlier. Plan to arrive two hours before domestic departures and four hours ahead of international flights when you fly during a peak period in general.

  • Travelling to Knoxville (and then exploring more of the United States!) is a snap with Delta. This popular carrier offers direct flights from Detroit Wayne County Airport to Knoxville Airport.

  • The majority of passengers choose to travel with Delta on this route.

  • With 77.51% of services landing on schedule, Delta is the most punctual carrier operating DTW to TYS flights.

  • We make it a breeze to book a flight with a stopover. To see all your options for tickets from Detroit Wayne County Airport to Knoxville Airport, uncheck 'Direct flights only.' Then, choose a flight offering a stop long enough to explore the city of your choice. Stopovers between DTW and TYS include:

    • Atlanta Hartsfield-Jackson Airport

    • Charlotte Douglas Airport

    • South Bend Airport

How to find the cheapest flights from Detroit Wayne County Airport (DTW) to Knoxville Airport (TYS)

  • The lowest price we've found for a one-way Detroit Wayne County Airport to Knoxville Airport flight is 85 €. A round-trip ticket is currently 163 €. Depending on the availability and when you book, these fares can change.

  • Don't leave everything to the last minute. You're more likely to find cheap tickets from DTW to TYS if you book ahead. Airlines often have some amazing early bird deals.

  • The cheapest month for flights from Detroit Wayne County Airport to Knoxville Airport is May. Use the 'Whole month' tool to see the lowest prices if you have a flexible schedule.

  • You don't need to check every day to find out if fares have dropped when you set up a Price Alert. We'll let you know as soon as the price changes on cheap flights from DTW to TYS.

  • Select your ideal departure and arrival times, airlines and number of stops with the filters. Or sort your results by 'Cheapest' to get the best deals on flights from Detroit Wayne County Airport to Knoxville Airport.

Handy information about Detroit Wayne County Airport (DTW)

  • DTW is located at 1 Detroit Metro Airport.

  • When it comes to the on-time performance of Detroit Wayne County Airport, data shows 74% of flights complete their journey on time.

  • To reach Detroit Wayne County Airport from central Detroit, it'll take around 30 minutes if you're planning to drive. This depends on traffic though. It's approximately 32 kilometres from the airport to the city centre.

  • The trip on public transport typically takes 1 hour.

  • Searching for a convenient hotel close to DTW? If you're catching an early flight from Detroit Wayne County Airport to Knoxville Airport, these accommodation options will have you sleeping moments from check-in:

Arriving at Knoxville Airport (TYS)

  • If you have a late Detroit Wayne County Airport to Knoxville Airport flight, nothing beats the convenience of being near the terminal. Pick up your bags from the carousel and then be resting not long after at one of these accommodation options near TYS:

  • Pick up a Knoxville Airport rental car and discover Knoxville and beyond with your own set of wheels. Budget, Alamo and Avis are well-known companies you can book with here.

  • Reserving your vehicle from Knoxville Airport around three weeks in advance can help you get the lowest rate.

When to fly to Knoxville Airport (TYS)

  • It's time to choose your travel dates for your flight from Detroit Wayne County Airport to Knoxville Airport. October is the busiest month to head to Knoxville. If you like a quieter vibe, go in March.

  • Book your flight from Detroit Wayne County Airport to Knoxville Airport for July if you'd like to visit Knoxville during its warmest month. Expect temperatures of between 17ºC (63ºF) and 32ºC (90ºF).

  • January sees average temperatures of between -6ºC (21ºF) and 11ºC (52ºF). Search for cheap tickets from DTW to TYS sometime around then if you want to travel when it's cooler.

Explore more of the United States

  • Knoxville has plenty going for it, but there are so many other corners of the United States just waiting to be explored. Around 451 kilometres north of Knoxville, a trip to Columbus will keep you busy. Start with attractions like Franklin Park Conservatory and Botanical Gardens, Whetstone Park / Park of Roses and Ohio Theatre.

  • If you're eager to discover another major stop in the United States, consider Indianapolis, roughly 467 kilometres north-west of Knoxville. Lucas Oil Stadium, Eiteljorg Museum and The Children's Museum of Indianapolis are the start of reasons to visit.

Plan the rest of your trip from Detroit to Knoxville

Prices shown on this page are estimated lowest prices only. Found in the last 12 days.