843 € Cheap Flights from Istanbul to Panama City

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Flight deals from Istanbul to Panama City

Looking for a cheap last-minute deal or the best return flight from Istanbul to Panama City? If you want to travel next month, return fares start from 1.145 €. Find the lowest prices on one-way and return tickets right here.

Panama City.843 € per passenger.Departing Wed, 17 Feb, returning Sat, 27 Feb.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Wed, 17 Feb, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Sat, 27 Feb, arriving in Istanbul.Price includes taxes and charges.From 843 €, select.

Panama City.846 € per passenger.Departing Fri, 26 Feb, returning Fri, 5 Mar.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Fri, 26 Feb, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Fri, 5 Mar, arriving in Istanbul.Price includes taxes and charges.From 846 €, select.

Panama City.846 € per passenger.Departing Fri, 5 Mar, returning Fri, 12 Mar.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Fri, 5 Mar, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Fri, 12 Mar, arriving in Istanbul.Price includes taxes and charges.From 846 €, select.

Panama City.846 € per passenger.Departing Sat, 15 May, returning Fri, 21 May.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Sat, 15 May, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Fri, 21 May, arriving in Istanbul.Price includes taxes and charges.From 846 €, select.

Panama City.847 € per passenger.Departing Sat, 24 Apr, returning Sat, 8 May.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Sat, 24 Apr, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Sat, 8 May, arriving in Istanbul.Price includes taxes and charges.From 847 €, select.

Panama City.847 € per passenger.Departing Wed, 21 Apr, returning Sun, 25 Apr.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Wed, 21 Apr, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Sun, 25 Apr, arriving in Istanbul.Price includes taxes and charges.From 847 €, select.

Panama City.849 € per passenger.Departing Fri, 2 Oct, returning Sat, 17 Oct.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Fri, 2 Oct, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Sat, 17 Oct, arriving in Istanbul.Price includes taxes and charges.From 849 €, select.

Panama City.870 € per passenger.Departing Wed, 9 Sep, returning Thu, 17 Sep.Return flight with Pegasus Airlines and Avianca.Outbound indirect flight with Pegasus Airlines, departs from Istanbul Sabiha on Wed, 9 Sep, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departs from Panama City Tocumen International on Thu, 17 Sep, arriving in Istanbul.Price includes taxes and charges.From 870 €, select.

Panama City.872 € per passenger.Departing Mon, 25 Jan, returning Mon, 1 Mar.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Mon, 25 Jan, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Mon, 1 Mar, arriving in Istanbul.Price includes taxes and charges.From 872 €, select.

Panama City.872 € per passenger.Departing Sun, 24 Jan, returning Sun, 28 Feb.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Sun, 24 Jan, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Sun, 28 Feb, arriving in Istanbul.Price includes taxes and charges.From 872 €, select.

Panama City.872 € per passenger.Departing Sat, 10 Oct, returning Fri, 20 Nov.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Sat, 10 Oct, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Fri, 20 Nov, arriving in Istanbul.Price includes taxes and charges.From 872 €, select.

Panama City.873 € per passenger.Departing Thu, 17 Sep, returning Thu, 1 Oct.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Thu, 17 Sep, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Thu, 1 Oct, arriving in Istanbul.Price includes taxes and charges.From 873 €, select.

Panama City.873 € per passenger.Departing Wed, 20 Jan, returning Wed, 27 Jan.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Wed, 20 Jan, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Wed, 27 Jan, arriving in Istanbul.Price includes taxes and charges.From 873 €, select.

Panama City.918 € per passenger.Departing Fri, 21 Aug, returning Tue, 10 Nov.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Fri, 21 Aug, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Tue, 10 Nov, arriving in Istanbul.Price includes taxes and charges.From 918 €, select.

Panama City.924 € per passenger.Departing Wed, 2 Jun, returning Tue, 15 Jun.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Wed, 2 Jun, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Tue, 15 Jun, arriving in Istanbul.Price includes taxes and charges.From 924 €, select.

Panama City.950 € per passenger.Departing Wed, 30 Dec, returning Thu, 21 Jan.Return flight with Air Europa.Outbound indirect flight with Air Europa, departs from Istanbul on Wed, 30 Dec, arriving in Panama City Tocumen International.Inbound indirect flight with Air Europa, departs from Panama City Tocumen International on Thu, 21 Jan, arriving in Istanbul.Price includes taxes and charges.From 950 €, select.

Find the cheapest month to fly from Istanbul to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Istanbul to Panama City flights are currently cheapest in February.

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Direct flights from Istanbul to Panama City

Alternative Istanbul to Panama City routes

Looking for the cheapest, fastest or easiest route from Istanbul to Panama City? You could fly into the following airports instead.

Istanbul to Panama City: Flight information

The things to know before you go.

Cheapest flight found	843 €
Cheapest month to fly	February
Average flight time	13 hrs, 54 mins
Most popular airline	Turkish Airlines
Average flights per week	7

Finding cheap flights from Istanbul to Panama City: Frequently asked questions

How many airports are there in Panama City?

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.

How much are return flights from Istanbul to Panama City?

The best price we found for a return flight from Istanbul to Panama City is 843 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

How long does it take to fly from Istanbul to Panama City?

13 hours and 54 minutes is the average flight time from Istanbul to Panama City.

Which airlines fly direct from Istanbul to Panama City?

Turkish Airlines and Copa fly direct from Istanbul to Panama City.

How many flights are there a week from Istanbul to Panama City?

As of July 2026, there are 28 flights per week flying from Istanbul to Panama City.

When is the cheapest time to fly from Istanbul to Panama City?

The cheapest month to fly from Istanbul to Panama City is usually February.

Which is the cheapest airport to fly into in Panama City?

If you're flying from Istanbul, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the centre of Panama City. We've found flights into this airport from 843 €.

Which upcoming date is cheapest to fly from Istanbul to Panama City on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Istanbul to Panama City on Wednesday, 17 February 2027.

Can I get a direct flight from Istanbul to Panama City?

Yes – the average flight time is 13 hours and 54 minutes.

How can I get the best flight deal from Istanbul to Panama City?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Panama City?

We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.

What’s the weather like in Panama City?

In July, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.

Which is the cheapest airline to fly from Istanbul to Panama City with?

The cheapest airline that flies to Panama City is Air Europa. And the cheapest airline that flies to Balboa Airport is Turkish Airlines.

Flying from Istanbul to Panama City: what you need to know

Istanbul is home to a couple of airports where you can set off on your adventure. Check out your options for reserving a flight from Istanbul to Panama City leaving from Istanbul Airport (IST) or Istanbul Sabiha Airport (SAW).
Step off your plane in Panama City at Panama City Tocumen International Airport (PTY) or Balboa Airport (BLB).
The average time for a direct Istanbul to Panama City flight is 13 hours 50 minutes.
The timezone in Panama City is UTC-5, which is eight hours behind Istanbul.
Istanbul Airport (IST) to Panama City Tocumen International Airport (PTY) is the most popular route between these two cities. There are three departures a week to choose from. If you have things to do before heading off, the last flight from Istanbul to Panama City is with Turkish Airlines at 14:10. Go for the first IST to PTY departure with Turkish Airlines at 13:50 to fit in more activities on your first day in Panama City.
To ensure you catch your Istanbul to Panama City flight, leave plenty of time for things like check-in and baggage drop. Arriving two hours before international departures and an hour before domestic flights is the standard rule.
Flying during a peak time like August? Major public holidays and other high seasons can lead to longer queues and delays at check-in and security. Be extra cautious and arrive up to four hours before international flights and two hours before domestic departures.

How to find the cheapest flights from Istanbul to Panama City

Book one month before travelling. Pricing trends show that this is the ideal window for finding cheap Istanbul to Panama City flights.
The best month for finding cheap plane tickets from Istanbul to Panama City is June. Use the 'Whole month' tool to compare flight prices, then select the dates with the lowest fares.
Save time searching for cheap flights from Istanbul to Panama City by setting up a Price Alert. We'll send you an email or notification through the app when a special offer becomes available.
Lock in a cheap Istanbul to Panama City flight with the help of our filters. Choose your ideal departure time, duration and airlines, then sort the results by 'Cheapest' for the best deals.

Flying from Istanbul

Istanbul Airport (IST)

You can book a direct flight from Istanbul to Panama City leaving from Istanbul Airport (IST). Start your journey at IST and end it at Panama City Tocumen International Airport (PTY).
Keep an eye out for deals with Turkish Airlines. This carrier offers direct Istanbul to Panama City plane tickets from IST.
Consider adding a stopover to possibly find a cheaper Istanbul to Panama City flight. Just uncheck 'Direct flights only' when browsing departures from Istanbul Airport. Take a break (and maybe save some cash) by stopping at one of these popular options:
- Paris Charles de Gaulle Airport (CDG)
- Bogota Airport (BOG)
- Havana Airport (HAV)
Located around 32 kilometres from the centre of Istanbul, IST can be reached in about 45 minutes by car (depending on traffic). The journey on public transport takes roughly 1 hour 10 minutes.
Searching for a handy hotel near Istanbul Airport? If you're boarding an early flight from Istanbul to Panama City, these stays will have you moments from check-in:

Istanbul Sabiha Airport (SAW)

Break up your Istanbul to Panama City flight with a stop at Amsterdam Schiphol Airport (AMS). One of the main stopovers between Istanbul Sabiha Airport and Panama City, it's a great opportunity to take a moment to relax.
SAW is around 31 kilometres from central Istanbul. It takes 1 hour 5 minutes or so to get to the airport in a car from the city centre. Public transport takes roughly 1 hour 40 minutes.
Kick off your holiday early with an additional night away from home. Before catching your flight from Istanbul to Panama City, kick back in one of these hotels close to Istanbul Sabiha Airport:
Istanbul Sabiha Airport has an on-time performance rate of 68%. This figure sheds light on how frequently flights departing from this airport make it to their destination on time.

Arriving in Panama City

Panama City Tocumen International Airport (PTY)

Panama City Tocumen International Airport (PTY) to central Panama City takes around 35 minutes by car. The centre is roughly 18 kilometres away.
If you're taking public transport, expect a journey time of about 50 minutes.
The last thing you need is a lengthy journey to your hotel if you're arriving on a late flight from Istanbul to Panama City. Reserve one of these accommodation options near PTY instead:
Grab a Panama City Tocumen International Airport rental car and discover Panama City and beyond with your own set of wheels. Avis, Dollar and MEX are top providers to choose from here.
To secure the lowest price, reserve your ride from Panama City Tocumen International Airport around three weeks ahead of your Istanbul to Panama City flight.

Panama City Paitilla Airport (PAC)

If you're staying in Panama City's centre (or just want to start sightseeing straight away), the city is around 5 kilometres from Panama City Paitilla Airport (PAC). Keep an eye out for any information desks to get directions after hopping off your flight from Istanbul to Panama City.
Place the 'Do not disturb' sign on your door and unwind at a hotel near PAC. Here are a few options where you can tuck yourself in after your flight from Istanbul to Panama City:
Thrifty, Avis and Alamo make picking up a Panama City Paitilla Airport rental car simple. These companies are located around or in the terminal and will have you on your way in a heartbeat.
Avoid last-minute price surges. Reserving your ride three weeks before your arrival at PAC will help you stay within budget.

Balboa Airport (BLB)

Travel to the centre after your flight from Istanbul to Panama City has touched down. Central Panama City is around 5 kilometres from Balboa Airport (BLB) and takes roughly 10 minutes to reach by taxi or ride-share.
Public transport can take you there in roughly 20 minutes.
Whether you're looking for a budget-friendly compact just for you or a spacious SUV to fit the whole crew comfortably, you'll find the ideal Balboa Airport rental car for your needs. Check out the range of wheels available from companies such as Sixt, Dollar and Thrifty.
Plan ahead and reap the rewards. Book your vehicle from BLB one week before your flight from Istanbul to Panama City for the most affordable rates.

Best time to go to Panama City

July is the busiest month for flights from Istanbul to Panama City. To steer clear of the crowds, visit Panama City in March.
The warmest month in Panama City is March, with temperatures ranging between 21ºC (70ºF) and 32ºC (90ºF). Lock in your Istanbul to Panama City ticket then if that's your definition of good weather.
Search for cheap flights from Istanbul to Panama City in January if you want to travel in cooler conditions. Temperatures are at their lowest then, ranging between 22ºC (72ºF) and 31ºC (88ºF) on average.

More about Panama City

Start your Panama City trip right by choosing the perfect place to stay. After booking your flight from Istanbul to Panama City, check out our selection of hotels including:
San Felipe and Metropolitan Cathedral Basilica of Santa Maria the Ancient are just a couple of the top attractions to add to your Panama City to-do list. Keep the sightseeing going at Independence Square.